Systems biology characterization of engineered tissues

Tissue engineering and molecular systems biology are inherently interdisciplinary fields that have been developed independently so far. In this review, we first provide a brief introduction to tissue engineering and to molecular systems biology. Next, we highlight some prominent applications of syst...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Annual review of biomedical engineering Ročník 15; s. 55
Hlavní autoři: Rajagopalan, Padmavathy, Kasif, Simon, Murali, T M
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 01.01.2013
Témata:
Algorithms
Animals
Bioengineering - methods
Computational Biology - methods
Humans
Microfluidics - methods
Protein Interaction Mapping - methods
Systems Biology - methods
Tissue Engineering - methods
ISSN:1545-4274, 1545-4274
On-line přístup:Zjistit podrobnosti o přístupu
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Tissue engineering and molecular systems biology are inherently interdisciplinary fields that have been developed independently so far. In this review, we first provide a brief introduction to tissue engineering and to molecular systems biology. Next, we highlight some prominent applications of systems biology techniques in tissue engineering. Finally, we outline research directions that can successfully blend these two fields. Through these examples, we propose that experimental and computational advances in molecular systems biology can lead to predictive models of bioengineered tissues that enhance our understanding of bioengineered systems. In turn, the unique challenges posed by tissue engineering will usher in new experimental techniques and computational advances in systems biology.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1545-4274
1545-4274
DOI:10.1146/annurev-bioeng-071811-150120