GIAE-DTI: Predicting Drug-Target Interactions Based on Heterogeneous Network and GIN-Based Graph Autoencoder

Accurate prediction of drug-target interactions (DTIs) is essential for advancing drug discovery and repurposing. However, the sparsity of DTI data limits the effectiveness of existing computational methods, which primarily focus on sparse DTI networks and have poor performance in aggregating inform...

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Bibliographic Details
Published in:IEEE journal of biomedical and health informatics Vol. 29; no. 11; pp. 7896 - 7909
Main Authors: Wang, Mengdi, Lei, Xiujuan, Liu, Lian, Chen, Jianrui, Wu, Fang-Xiang
Format: Journal Article
Language:English
Published: United States IEEE 01.11.2025
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ISSN:2168-2194, 2168-2208, 2168-2208
Online Access:Get full text
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