Graduate Student Literature Review: Utilization of differential somatic cell count in the detection and management of mastitis
The list of standard abbreviations for JDS is available at adsa.org/jds-abbreviations-24. Nonstandard abbreviations are available in the Notes. Mastitis remains a substantial challenge for the dairy industry. Producers strive to maximize dairy cow production, health, and well-being, while also reduc...
Saved in:
| Published in: | Journal of dairy science Vol. 108; no. 12; pp. 13621 - 13630 |
|---|---|
| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
Elsevier Inc
01.12.2025
Elsevier |
| Subjects: | |
| ISSN: | 0022-0302, 1525-3198, 1525-3198 |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | The list of standard abbreviations for JDS is available at adsa.org/jds-abbreviations-24. Nonstandard abbreviations are available in the Notes.
Mastitis remains a substantial challenge for the dairy industry. Producers strive to maximize dairy cow production, health, and well-being, while also reducing antibiotic usage. Limitations to current mastitis measures have led to the exploration of the use of differential SCC (DSCC). Rather than evaluating the total cell population within milk (i.e., SCC), DSCC focuses on the distribution of individual white blood cell (WBC) types. During an infection, the number of WBC will change dramatically as a result of inflammation. Predominant WBC consist of neutrophils, macrophages, and lymphocytes. A more in-depth assessment of the immune response provided by DSCC may address limitations of other diagnostic parameters. Multiple methods exist to enumerate DSCC, with the most common being fluorescence microscopy and flow cytometry. However, there is still much unknown about the biological factors that affect DSCC. In order for DSCC to be appropriately used in the dairy industry, there must be a consensus on how DSCC is reported and a greater understanding of the physiological and environmental factors that affect cell populations. This review brings together current information on the performance of DSCC in IMI detection and related factors to help guide future directions for research. |
|---|---|
| AbstractList | The list of standard abbreviations for JDS is available at adsa.org/jds-abbreviations-24. Nonstandard abbreviations are available in the Notes.
Mastitis remains a substantial challenge for the dairy industry. Producers strive to maximize dairy cow production, health, and well-being, while also reducing antibiotic usage. Limitations to current mastitis measures have led to the exploration of the use of differential SCC (DSCC). Rather than evaluating the total cell population within milk (i.e., SCC), DSCC focuses on the distribution of individual white blood cell (WBC) types. During an infection, the number of WBC will change dramatically as a result of inflammation. Predominant WBC consist of neutrophils, macrophages, and lymphocytes. A more in-depth assessment of the immune response provided by DSCC may address limitations of other diagnostic parameters. Multiple methods exist to enumerate DSCC, with the most common being fluorescence microscopy and flow cytometry. However, there is still much unknown about the biological factors that affect DSCC. In order for DSCC to be appropriately used in the dairy industry, there must be a consensus on how DSCC is reported and a greater understanding of the physiological and environmental factors that affect cell populations. This review brings together current information on the performance of DSCC in IMI detection and related factors to help guide future directions for research. Mastitis remains a substantial challenge for the dairy industry. Producers strive to maximize dairy cow production, health, and well-being, while also reducing antibiotic usage. Limitations to current mastitis measures have led to the exploration of the use of differential SCC (DSCC). Rather than evaluating the total cell population within milk (i.e., SCC), DSCC focuses on the distribution of individual white blood cell (WBC) types. During an infection, the number of WBC will change dramatically as a result of inflammation. Predominant WBC consist of neutrophils, macrophages, and lymphocytes. A more in-depth assessment of the immune response provided by DSCC may address limitations of other diagnostic parameters. Multiple methods exist to enumerate DSCC, with the most common being fluorescence microscopy and flow cytometry. However, there is still much unknown about the biological factors that affect DSCC. In order for DSCC to be appropriately used in the dairy industry, there must be a consensus on how DSCC is reported and a greater understanding of the physiological and environmental factors that affect cell populations. This review brings together current information on the performance of DSCC in IMI detection and related factors to help guide future directions for research. Mastitis remains a substantial challenge for the dairy industry. Producers strive to maximize dairy cow production, health, and well-being, while also reducing antibiotic usage. Limitations to current mastitis measures have led to the exploration of the use of differential SCC (DSCC). Rather than evaluating the total cell population within milk (i.e., SCC), DSCC focuses on the distribution of individual white blood cell (WBC) types. During an infection, the number of WBC will change dramatically as a result of inflammation. Predominant WBC consist of neutrophils, macrophages, and lymphocytes. A more in-depth assessment of the immune response provided by DSCC may address limitations of other diagnostic parameters. Multiple methods exist to enumerate DSCC, with the most common being fluorescence microscopy and flow cytometry. However, there is still much unknown about the biological factors that affect DSCC. In order for DSCC to be appropriately used in the dairy industry, there must be a consensus on how DSCC is reported and a greater understanding of the physiological and environmental factors that affect cell populations. This review brings together current information on the performance of DSCC in IMI detection and related factors to help guide future directions for research.Mastitis remains a substantial challenge for the dairy industry. Producers strive to maximize dairy cow production, health, and well-being, while also reducing antibiotic usage. Limitations to current mastitis measures have led to the exploration of the use of differential SCC (DSCC). Rather than evaluating the total cell population within milk (i.e., SCC), DSCC focuses on the distribution of individual white blood cell (WBC) types. During an infection, the number of WBC will change dramatically as a result of inflammation. Predominant WBC consist of neutrophils, macrophages, and lymphocytes. A more in-depth assessment of the immune response provided by DSCC may address limitations of other diagnostic parameters. Multiple methods exist to enumerate DSCC, with the most common being fluorescence microscopy and flow cytometry. However, there is still much unknown about the biological factors that affect DSCC. In order for DSCC to be appropriately used in the dairy industry, there must be a consensus on how DSCC is reported and a greater understanding of the physiological and environmental factors that affect cell populations. This review brings together current information on the performance of DSCC in IMI detection and related factors to help guide future directions for research. |
| Author | Callaway, Todd R. Burner, Carmen Ryman, Valerie E. |
| Author_xml | – sequence: 1 givenname: Carmen orcidid: 0009-0004-9243-6609 surname: Burner fullname: Burner, Carmen email: burne390@umn.edu organization: Department of Animal and Dairy Science, University of Georgia, Athens, GA 30602 – sequence: 2 givenname: Todd R. orcidid: 0000-0002-3310-4979 surname: Callaway fullname: Callaway, Todd R. organization: Department of Animal and Dairy Science, University of Georgia, Athens, GA 30602 – sequence: 3 givenname: Valerie E. orcidid: 0000-0002-1054-9537 surname: Ryman fullname: Ryman, Valerie E. email: vryman@uga.edu organization: Department of Physiology and Pharmacology, University of Georgia, Athens, GA 30602 |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/41130392$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1UU1vEzEUtFARTQtXjshHLgn-2o2XG6qgVIqEBPRsPdvPxdHuutheEBz47ThJ6Y2T9Z5n5mlmLsjZnGYk5CVnG8l7_Wbvy0Yw0a1FP6juCVnxrg2SD_qMrBgTYs0kE-fkopR9G7lg3TNyrjiXTA5iRf5cZ_ALVKRf6uJxrnQXK2aoS0b6GX9E_PmW3tY4xt9QY5ppCtTHEDA3bISRljS1D0cdjiN1aWkKcab1G1KPFd2RA7OnE8xwh9PhQpOYoNRYY3lOngYYC754eC_J7Yf3X68-rnefrm-u3u3WTormh0s_eNBC2a3qtiIM0rneWt977rYMtUJvGQbkQeuhs0FYJxzj3GLXttLJS3Jz0vUJ9uY-xwnyL5MgmuMi5TsDudkY0QyuC8IpqUGjUn03hMFjkNqCtk4Bb1qvT1r3OX1fsFQzxXKwDzOmpRgp-kbjvRIN-uoButgJ_ePhf_k3wOYEcDmVkjE8Qjgzh4JNK9gcCjbHghtBnwjY0mrtZFNcxNmhj7ml3ezE_1H_AqrirfU |
| Cites_doi | 10.3168/jds.2008-1497 10.3389/fvets.2018.00273 10.3168/jds.2016-12409 10.3390/s100907991 10.3168/jds.S0022-0302(00)74878-8 10.3168/jds.2012-5331 10.3168/jds.2017-14152 10.3168/jds.2010-3930 10.1159/000127412 10.14202/vetworld.2018.562-577 10.3168/jds.2018-16092 10.1177/104063870101300506 10.3390/agriculture12091437 10.1016/j.jtbi.2023.111718 10.1016/j.prevetmed.2015.11.006 10.1371/journal.pone.0275755 10.3168/jds.2023-23388 10.3168/jds.2023-23848 10.3168/jds.2023-23639 10.3168/jds.2010-4074 10.1016/j.prevetmed.2020.105079 10.3168/jds.2023-24626 10.1080/1828051X.2020.1784804 10.1017/S002202990600238X 10.1016/j.cvfa.2018.07.005 10.3168/jds.2020-19299 10.3168/jds.2020-19378 10.2460/ajvr.1986.47.03.663 10.3389/fvets.2020.609055 10.1017/S0022029900020860 10.2527/jas.2007-0302 10.17221/222/2015-VETMED 10.2527/jas.2008-1187 10.3168/jds.2016-12478 10.3168/jds.2024-25292 10.3389/fcimb.2024.1406168 10.3168/jds.2019-16355 10.3168/jds.2019-16523 10.3168/jds.2024-25357 10.1093/jas/skac406 10.3168/jds.2021-20395 10.3390/ani10040604 10.3168/jds.2019-17361 10.3168/jds.2024-25404 10.1016/j.animal.2023.100982 10.1023/A:1020347818725 10.1245/s10434-011-1814-0 10.3168/jds.S0022-0302(01)70173-7 10.3168/jds.2011-4348 10.1080/1828051X.2018.1533391 10.3168/jds.2012-6298 10.3168/jds.2017-12548 10.1128/CDLI.11.3.463-472.2004 10.1080/01652176.2019.1642546 10.3168/jds.2023-24086 |
| ContentType | Journal Article |
| Copyright | 2025 American Dairy Science Association The Authors. Published by Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). 2025, The Authors. Published by Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| Copyright_xml | – notice: 2025 American Dairy Science Association – notice: The Authors. Published by Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). – notice: 2025, The Authors. Published by Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| DBID | 6I. AAFTH AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 DOA |
| DOI | 10.3168/jds.2025-26945 |
| DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Agriculture |
| EISSN | 1525-3198 |
| EndPage | 13630 |
| ExternalDocumentID | oai_doaj_org_article_9c5f2c438a8e44659f9def38ba8bc4a1 41130392 10_3168_jds_2025_26945 S0022030225008306 |
| Genre | Journal Article Review |
| GroupedDBID | --- --K -~X .GJ 0R~ 186 18M 1B1 29K 2WC 36B 4.4 457 4G. 53G 5GY 5VS 6I. 7-5 7X2 7X7 7XC 88E 8FE 8FG 8FH 8FI 8FJ 8FW 8R4 8R5 8VB AAEDT AAEDW AAFTH AAFWJ AAHBH AALRI AAQFI AAQXK AAWRB AAXUO AAYWO ABCQX ABJCF ABUWG ABWVN ACGFO ACGFS ACIWK ACRPL ACVFH ADBBV ADCNI ADMHG ADMUD ADNMO ADVLN AEGXH AENEX AEUPX AEUYN AFFHD AFJKZ AFKRA AFPKN AFPUW AFRAH AFTJW AGQPQ AHMBA AI. AIAGR AIGII AITUG AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ APXCP ASPBG ATCPS AVWKF AZFZN BELOY BENPR BGLVJ BHPHI BPHCQ BVXVI C1A CCPQU CS3 D-I DU5 E3Z EBS EJD F5P FDB FEDTE FGOYB FYUFA GBLVA GROUPED_DOAJ GX1 HCIFZ HMCUK HVGLF HZ~ K1G L6V L7B M0K M1P M41 M7S N9A NHB O9- OK1 P2P PATMY PHGZM PHGZT PJZUB PPXIY PQGLB PQQKQ PROAC PSQYO PTHSS PYCSY Q2X QII QWB R2- ROL RWL S0X SEL SES SSZ TAE TDS TWZ U5U UHB UKHRP VH1 WOQ XH2 XOL ZGI ZL0 ZXP ~KM AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 |
| ID | FETCH-LOGICAL-c3225-13d9da824b74572f93cc6bbd6d1c70e84edb0efe1f8895bf2bc2c011be5efe3c3 |
| IEDL.DBID | DOA |
| ISSN | 0022-0302 1525-3198 |
| IngestDate | Mon Nov 24 19:20:58 EST 2025 Sat Oct 25 08:53:26 EDT 2025 Sat Nov 22 01:41:10 EST 2025 Thu Nov 27 00:56:38 EST 2025 Sat Nov 29 17:04:01 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 12 |
| Keywords | intramammary infection dairy cow neutrophils somatic cell count |
| Language | English |
| License | This is an open access article under the CC BY license. The Authors. Published by Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c3225-13d9da824b74572f93cc6bbd6d1c70e84edb0efe1f8895bf2bc2c011be5efe3c3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
| ORCID | 0000-0002-3310-4979 0000-0002-1054-9537 0009-0004-9243-6609 |
| OpenAccessLink | https://doaj.org/article/9c5f2c438a8e44659f9def38ba8bc4a1 |
| PMID | 41130392 |
| PQID | 3264651642 |
| PQPubID | 23479 |
| PageCount | 10 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_9c5f2c438a8e44659f9def38ba8bc4a1 proquest_miscellaneous_3264651642 pubmed_primary_41130392 crossref_primary_10_3168_jds_2025_26945 elsevier_sciencedirect_doi_10_3168_jds_2025_26945 |
| PublicationCentury | 2000 |
| PublicationDate | 2025-12-01 |
| PublicationDateYYYYMMDD | 2025-12-01 |
| PublicationDate_xml | – month: 12 year: 2025 text: 2025-12-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Journal of dairy science |
| PublicationTitleAlternate | J Dairy Sci |
| PublicationYear | 2025 |
| Publisher | Elsevier Inc Elsevier |
| Publisher_xml | – name: Elsevier Inc – name: Elsevier |
| References | Kirkeby, Toft, Schwarz, Farre, Nielsen, Zervens, Hechinger, Halasa (bib28) 2020; 103 Schwarz, Santschi, Durocher, Lefebvre (bib50) 2020; 181 Zecconi, Vairani, Cipolla, Rizzi, Zanini (bib61) 2019; 18 Bannerman, Paape, Lee, Zhao, Hope, Rainard (bib5) 2004; 11 Sordillo, Streicher (bib52) 2002; 7 Du, Lu, Zheng, Liu, Yang, Yi, Zhu, Shen (bib17) 2024; 14 Wall, Wellnitz, Bruckmaier, Schwarz (bib55) 2018; 101 Stocco, Cipolat-Gotet, Stefanon, Zecconi, Francescutti, Mountricha, Summer (bib53) 2023; 101 Schwarz, Diesterbeck, König, Brügemann, Schlez, Zschöck, Wolter, Czerny (bib49) 2011; 94 Yamanaka, Matsumoto, Teramukai, Ishiwata, Nagai, Fukushima (bib58) 2007; 73 Pilla, Schwarz, König, Piccinini (bib40) 2012; 95 Bannerman (bib4) 2009; 87 Zajac, Zubricka, Capla, Zelenakova (bib59) 2016; 61 Sordillo (bib51) 2018; 34 Pinzón-Sánchez, Cabrera, Ruegg (bib42) 2011; 94 Pillai, Kunze, Sordillo, Jayarao (bib41) 2001; 84 Condas, De Buck, Nobrega, Carson, Naushad, De Vliegher, Zadoks, Middleton, Dufour, Kastelic, Barkema (bib12) 2017; 100 Lee, Wooding, Kemp (bib29) 1980; 47 Rasmussen, Barkema, Osei, Taylor, Shaw, Conrady, Chaters, Muñoz, Hall, Apenteng, Rushton, Torgerson (bib43) 2024; 107 Azab, Bhatt, Phookan, Murukutla, Kohn, Terjanian, Widmann (bib3) 2012; 19 Mehne, Drees, Schuberth, Sauter-Louis, Zerbe, Petzl (bib32) 2010; 63 De Vliegher, Fox, Piepers, McDougall, Barkema (bib15) 2012; 95 Mondini, Gislon, Zucali, Sandrucci, Tamburini, Bava (bib35) 2025; 108 Chakraborty, Dhama, Tiwari, Iqbal Yatoo, Khurana, Khandia, Munjal, Munuswamy, Kumar, Singh, Singh, Gupta, Chaicumpa (bib10) 2019; 39 Henningsen, Reimert, Denwood, Gussmann, Kirkeby, Nielsen (bib24) 2024; 579 Lozada-Soto, Maltecca, Anderson, Tiezzi (bib31) 2020; 103 De Vries (bib16) 2020; 103 Norman, Guinan, Megonigal, Dürr (bib36) 2021 Godden, Royster, Timmerman, Rapnicki, Green (bib21) 2017; 100 Rollin, Dhuyvetter, Overton (bib46) 2015; 122 Bradley, Green (bib8) 2009; 92 USDA ERS (USDA Economic Research Service) (bib54) 2025 Pérez-Cabal, López-Paredes, Cervantes, Gutiérrez, Charfeddine (bib38) 2024; 107 Rivas, Quimby, Blue, Coksaygan (bib44) 2001; 13 Zecconi, Dell'Orco, Vairani, Rizzi, Cipolla, Zanini (bib60) 2020; 10 Romero, Benavides, Meza (bib47) 2018; 5 Fonseca, Kurban, Roy, Santschi, Molgat, Dufour (bib18) 2025; 108 Ablondi, Summer, Stocco, Degano, Vicario, Stefanon, Sabbioni, Cipolat-Gotet (bib1) 2023; 106 Cobirka, Tancin, Slama (bib11) 2020; 10 Williamson, Callaway, Rollin, Ryman (bib57) 2022; 12 Freu, Gioia, Gross, Biscarini, Virkler, Watters, Addis, Franklin-Guild, Runyan, Masroure, Bronzo, dos Santos, Moroni (bib19) 2024; 107 Zhao, Lacasse (bib63) 2008; 86 Dal Prà, Biscarini, Cavani, Bacchelli, Iotti, Borghi, Nocetti, Moroni (bib13) 2022; 17 Damm, Holm, Blaabjerg, Bro, Schwarz (bib14) 2017; 100 Leite de Campos, Gonçalves, Kates, Steinberger, Sethi, Suen, Shutske, Safdar, Goldberg, Ruegg (bib30) 2023; 106 Hogeveen, Kamphuis, Steeneveld, Mollenhorst (bib25) 2010; 10 Capuco, Paape, Nickerson (bib9) 1986; 47 Pegolo, Mota, Bisutti, Martinez-Castillero, Giannuzzi, Gallo, Schiavon, Tagliapietra, Revello Chion, Trevisi, Negrini, Ajmone Marsan, Cecchinato (bib37) 2021; 104 Merle, Schröder, Hamann (bib33) 2007; 74 Schalm, Noorlander (bib48) 1957; 130 Alhussien, Dang (bib2) 2018; 11 Bobbo, Penasa, Cassandro (bib7) 2020; 19 Haw, Adkins, Bernier Gosselin, Poock, Middleton (bib23) 2024; 107 Robles, Nolan, Fendley, Stokley, France, Ferrell, Costa (bib45) 2021; 104 Halasa, Kirkeby (bib22) 2020; 7 Zecconi, Zaghen, Meroni, Sora, Martino, Laterza, Zanini (bib62) 2023; 13 Kelly, Tiernan, O'Sullivan, Joyce (bib26) 2000; 83 Garcia-Flores, Dawid De Vera, Pilo, Rego, Gomez-Casado, Arranz-Salas, Hierro Martín, Alcaide, Torres, Ortega-Gomez, Boughanem, Macias-Gonzalez (bib20) 2024; 15 Mondini, Gislon, Zucali, Sandrucci, Tamburini, Bava (bib34) 2023; 17 Pilla, Malvisi, Snel, Schwarz, König, Czerny, Piccinini (bib39) 2013; 96 Kirkeby, Schwarz, Denwood, Farre, Nielsen, Gussmann, Toft, Halasa (bib27) 2021; 104 Bobbo, Penasa, Cassandro (bib6) 2019; 102 Wardlaw, S. C., R. A. Levine, and R. R. Rodriguez. 2002. Determination of white blood cell differential and reticulocyte counts. Becton Dickinson & Co. US Pat. No 6,350,613. Capuco (10.3168/jds.2025-26945_bib9) 1986; 47 Hogeveen (10.3168/jds.2025-26945_bib25) 2010; 10 Lee (10.3168/jds.2025-26945_bib29) 1980; 47 Du (10.3168/jds.2025-26945_bib17) 2024; 14 Pilla (10.3168/jds.2025-26945_bib40) 2012; 95 Bannerman (10.3168/jds.2025-26945_bib5) 2004; 11 Damm (10.3168/jds.2025-26945_bib14) 2017; 100 Pillai (10.3168/jds.2025-26945_bib41) 2001; 84 Wall (10.3168/jds.2025-26945_bib55) 2018; 101 Williamson (10.3168/jds.2025-26945_bib57) 2022; 12 Sordillo (10.3168/jds.2025-26945_bib52) 2002; 7 Halasa (10.3168/jds.2025-26945_bib22) 2020; 7 Kirkeby (10.3168/jds.2025-26945_bib27) 2021; 104 Robles (10.3168/jds.2025-26945_bib45) 2021; 104 Azab (10.3168/jds.2025-26945_bib3) 2012; 19 Romero (10.3168/jds.2025-26945_bib47) 2018; 5 Dal Prà (10.3168/jds.2025-26945_bib13) 2022; 17 Zecconi (10.3168/jds.2025-26945_bib61) 2019; 18 Zecconi (10.3168/jds.2025-26945_bib62) 2023; 13 Bobbo (10.3168/jds.2025-26945_bib6) 2019; 102 Zajac (10.3168/jds.2025-26945_bib59) 2016; 61 Henningsen (10.3168/jds.2025-26945_bib24) 2024; 579 Zecconi (10.3168/jds.2025-26945_bib60) 2020; 10 Schalm (10.3168/jds.2025-26945_bib48) 1957; 130 Haw (10.3168/jds.2025-26945_bib23) 2024; 107 Pinzón-Sánchez (10.3168/jds.2025-26945_bib42) 2011; 94 Pérez-Cabal (10.3168/jds.2025-26945_bib38) 2024; 107 Cobirka (10.3168/jds.2025-26945_bib11) 2020; 10 Freu (10.3168/jds.2025-26945_bib19) 2024; 107 Pilla (10.3168/jds.2025-26945_bib39) 2013; 96 Sordillo (10.3168/jds.2025-26945_bib51) 2018; 34 Godden (10.3168/jds.2025-26945_bib21) 2017; 100 Rivas (10.3168/jds.2025-26945_bib44) 2001; 13 Garcia-Flores (10.3168/jds.2025-26945_bib20) 2024; 15 USDA ERS (USDA Economic Research Service) (10.3168/jds.2025-26945_bib54) 2025 Condas (10.3168/jds.2025-26945_bib12) 2017; 100 Schwarz (10.3168/jds.2025-26945_bib50) 2020; 181 Schwarz (10.3168/jds.2025-26945_bib49) 2011; 94 Bannerman (10.3168/jds.2025-26945_bib4) 2009; 87 Norman (10.3168/jds.2025-26945_bib36) Mondini (10.3168/jds.2025-26945_bib35) 2025; 108 Rollin (10.3168/jds.2025-26945_bib46) 2015; 122 Stocco (10.3168/jds.2025-26945_bib53) 2023; 101 Bobbo (10.3168/jds.2025-26945_bib7) 2020; 19 Kelly (10.3168/jds.2025-26945_bib26) 2000; 83 Bradley (10.3168/jds.2025-26945_bib8) 2009; 92 Chakraborty (10.3168/jds.2025-26945_bib10) 2019; 39 De Vries (10.3168/jds.2025-26945_bib16) 2020; 103 Merle (10.3168/jds.2025-26945_bib33) 2007; 74 De Vliegher (10.3168/jds.2025-26945_bib15) 2012; 95 Mehne (10.3168/jds.2025-26945_bib32) 2010; 63 Ablondi (10.3168/jds.2025-26945_bib1) 2023; 106 Lozada-Soto (10.3168/jds.2025-26945_bib31) 2020; 103 Kirkeby (10.3168/jds.2025-26945_bib28) 2020; 103 Alhussien (10.3168/jds.2025-26945_bib2) 2018; 11 Pegolo (10.3168/jds.2025-26945_bib37) 2021; 104 Zhao (10.3168/jds.2025-26945_bib63) 2008; 86 Mondini (10.3168/jds.2025-26945_bib34) 2023; 17 Rasmussen (10.3168/jds.2025-26945_bib43) 2024; 107 Leite de Campos (10.3168/jds.2025-26945_bib30) 2023; 106 10.3168/jds.2025-26945_bib56 Yamanaka (10.3168/jds.2025-26945_bib58) 2007; 73 Fonseca (10.3168/jds.2025-26945_bib18) 2025; 108 |
| References_xml | – volume: 107 start-page: 11301 year: 2024 end-page: 11310 ident: bib38 article-title: Genetic evaluation of udder health traits in Spanish Holstein cows publication-title: J. Dairy Sci. – volume: 101 start-page: 5362 year: 2018 end-page: 5373 ident: bib55 article-title: Differential somatic cell count in milk before, during, and after lipopolysaccharide- and lipoteichoic-acid-induced mastitis in dairy cows publication-title: J. Dairy Sci. – volume: 34 start-page: 507 year: 2018 end-page: 523 ident: bib51 article-title: Mammary gland immunobiology and resistance to mastitis publication-title: Vet. Clin. North Am. Food Anim. Pract. – volume: 579 year: 2024 ident: bib24 article-title: Using registry data to identify individual dairy cows with abnormal patterns in routinely recorded somatic cell counts publication-title: J. Theor. Biol. – volume: 108 start-page: 2721 year: 2025 end-page: 2733 ident: bib35 article-title: Factors influencing somatic cell count and leukocyte composition in cow milk: A field study publication-title: J. Dairy Sci. – volume: 10 start-page: 7991 year: 2010 end-page: 8009 ident: bib25 article-title: Sensors and clinical mastitis–the quest for the perfect alert publication-title: Sensors (Basel) – volume: 106 start-page: 9071 year: 2023 end-page: 9077 ident: bib1 article-title: Heritability and genetic correlations of total and differential somatic cell count with milk yield and composition traits in Italian Simmental cows publication-title: J. Dairy Sci. – volume: 19 start-page: 217 year: 2012 end-page: 224 ident: bib3 article-title: Usefulness of the neutrophil-to-lymphocyte ratio in predicting short- and long-term mortality in breast cancer patients publication-title: Ann. Surg. Oncol. – volume: 100 start-page: 5592 year: 2017 end-page: 5612 ident: bib12 article-title: Prevalence of non-aureus staphylococci species causing intramammary infections in Canadian dairy herds publication-title: J. Dairy Sci. – volume: 181 year: 2020 ident: bib50 article-title: Evaluation of the new differential somatic cell count parameter as a rapid and inexpensive supplementary tool for udder health management through regular milk recording publication-title: Prev. Vet. Med. – volume: 92 start-page: 1941 year: 2009 end-page: 1953 ident: bib8 article-title: Factors affecting cure when treating bovine clinical mastitis with cephalosporin-based intramammary preparations publication-title: J. Dairy Sci. – volume: 107 start-page: 6945 year: 2024 end-page: 6970 ident: bib43 article-title: Global losses due to dairy cattle diseases: A comorbidity-adjusted economic analysis publication-title: J. Dairy Sci. – volume: 86 start-page: 57 year: 2008 end-page: 65 ident: bib63 article-title: Mammary tissue damage during bovine mastitis: Causes and control publication-title: J. Anim. Sci. – volume: 18 start-page: 460 year: 2019 end-page: 465 ident: bib61 article-title: Assessment of subclinical mastitis diagnostic accuracy by differential cell count in individual cow milk publication-title: Ital. J. Anim. Sci. – volume: 108 start-page: 3929 year: 2025 end-page: 3941 ident: bib18 article-title: Usefulness of differential somatic cell count for udder health monitoring: Diagnostic performance of somatic cell count, and differential somatic cell count for diagnosing of intramammary infections in dairy herds with automated milking systems publication-title: J. Dairy Sci. – volume: 96 start-page: 1653 year: 2013 end-page: 1660 ident: bib39 article-title: Differential cell count as an alternative method to diagnose dairy cow mastitis publication-title: J. Dairy Sci. – volume: 104 start-page: 4942 year: 2021 end-page: 4949 ident: bib45 article-title: Technical note: Evaluation of a commercial on-farm milk leukocyte differential tester to identify subclinical mastitis cases in dairy cows publication-title: J. Dairy Sci. – volume: 95 start-page: 4410 year: 2012 end-page: 4420 ident: bib40 article-title: Microscopic differential cell counting to identify inflammatory reactions in dairy cow quarter milk samples publication-title: J. Dairy Sci. – volume: 10 year: 2020 ident: bib11 article-title: Epidemiology and classification of mastitis publication-title: Animals (Basel) – volume: 17 year: 2022 ident: bib13 article-title: Relationship between total and differential quarter somatic cell counts at dry-off and early lactation publication-title: PLoS One – volume: 13 year: 2023 ident: bib62 article-title: Early milk total and differential cell counts as a diagnostic tool to improve antimicrobial therapy protocols publication-title: Animals (Basel) – volume: 94 start-page: 5033 year: 2011 end-page: 5044 ident: bib49 article-title: Flow cytometric differential cell counts in milk for the evaluation of inflammatory reactions in clinically healthy and subclinically infected bovine mammary glands publication-title: J. Dairy Sci. – volume: 12 year: 2022 ident: bib57 article-title: Association of milk somatic cell count with bacteriological cure of intramammary infection—A review publication-title: Agriculture – volume: 122 start-page: 257 year: 2015 end-page: 264 ident: bib46 article-title: The cost of clinical mastitis in the first 30 days of lactation: An economic modeling tool publication-title: Prev. Vet. Med. – volume: 87 start-page: 10 year: 2009 end-page: 25 ident: bib4 article-title: Pathogen-dependent induction of cytokines and other soluble inflammatory mediators during intramammary infection of dairy cows publication-title: J. Anim. Sci. – volume: 7 start-page: 135 year: 2002 end-page: 146 ident: bib52 article-title: Mammary gland immunity and mastitis susceptibility publication-title: J. Mammary Gland Biol. Neoplasia – year: 2021 ident: bib36 article-title: Milk somatic cell count from Dairy Herd Improvement herds during 2021. Council on Dairy Cattle Breeding. Report Number 301-525-2006 – volume: 84 start-page: 1413 year: 2001 end-page: 1420 ident: bib41 article-title: Application of differential inflammatory cell count as a tool to monitor udder health publication-title: J. Dairy Sci. – reference: Wardlaw, S. C., R. A. Levine, and R. R. Rodriguez. 2002. Determination of white blood cell differential and reticulocyte counts. Becton Dickinson & Co. US Pat. No 6,350,613. – volume: 15 year: 2024 ident: bib20 article-title: Increased neutrophil counts are associated with poor overall survival in patients with colorectal cancer: A five-year retrospective analysis publication-title: Front. Immunol. – volume: 7 year: 2020 ident: bib22 article-title: Differential somatic cell count: Value for udder health management publication-title: Front. Vet. Sci. – volume: 5 start-page: 273 year: 2018 ident: bib47 article-title: Assessing financial impacts of subclinical mastitis on Colombian dairy farms publication-title: Front. Vet. Sci. – volume: 130 start-page: 199 year: 1957 end-page: 204 ident: bib48 article-title: Experiments and observations leading to development of the California mastitis test publication-title: J. Am. Vet. Med. Assoc. – volume: 10 start-page: 604 year: 2020 ident: bib60 article-title: Differential somatic cell count as a marker for changes of milk composition in cows with very low somatic cell count publication-title: Animals (Basel) – volume: 39 start-page: 76 year: 2019 end-page: 94 ident: bib10 article-title: Technological interventions and advances in the diagnosis of intramammary infections in animals with emphasis on bovine population-a review publication-title: Vet. Q. – volume: 101 year: 2023 ident: bib53 article-title: Herd and animal factors affect the variability of total and differential somatic cell count in bovine milk publication-title: J. Anim. Sci. – volume: 100 start-page: 6527 year: 2017 end-page: 6544 ident: bib21 article-title: Evaluation of an automated milk leukocyte differential test and the California Mastitis Test for detecting intramammary infection in early- and late-lactation quarters and cows publication-title: J. Dairy Sci. – volume: 103 start-page: 1759 year: 2020 end-page: 1775 ident: bib28 article-title: Differential somatic cell count as an additional indicator for intramammary infections in dairy cows publication-title: J. Dairy Sci. – volume: 11 start-page: 463 year: 2004 end-page: 472 ident: bib5 article-title: and publication-title: Clin. Vaccine Immunol. – year: 2025 ident: bib54 article-title: Livestock, Dairy, and Poultry Outlook: February 2025. Report No. LDP-M-368 – volume: 107 start-page: 3813 year: 2024 end-page: 3823 ident: bib19 article-title: Frequency of non- publication-title: J. Dairy Sci. – volume: 104 start-page: 3427 year: 2021 end-page: 3438 ident: bib27 article-title: Dynamics of somatic cell count (SCC) and differential SCC during and following intramammary infections publication-title: J. Dairy Sci. – volume: 83 start-page: 300 year: 2000 end-page: 304 ident: bib26 article-title: Correlation between bovine milk somatic cell count and polymorphonuclear leukocyte level for samples of bulk milk and milk from individual cows publication-title: J. Dairy Sci. – volume: 106 start-page: 9276 year: 2023 end-page: 9286 ident: bib30 article-title: Variation in partial direct costs of treating clinical mastitis among 37 Wisconsin dairy farms publication-title: J. Dairy Sci. – volume: 95 start-page: 1025 year: 2012 end-page: 1040 ident: bib15 article-title: Invited review: Mastitis in dairy heifers: nature of the disease, potential impact, prevention, and control publication-title: J. Dairy Sci. – volume: 13 start-page: 399 year: 2001 end-page: 407 ident: bib44 article-title: Longitudinal evaluation of bovine mammary gland health status by somatic cell counting, flow cytometry, and cytology publication-title: J. Vet. Diagn. Invest. – volume: 102 start-page: 4275 year: 2019 end-page: 4279 ident: bib6 article-title: Short communication: Genetic aspects of milk differential somatic cell count in Holstein cows: A preliminary analysis publication-title: J. Dairy Sci. – volume: 63 start-page: 235 year: 2010 end-page: 238 ident: bib32 article-title: Accurate and rapid flow cytometric leukocyte differentiation in low and high somatic cell count milk publication-title: Milchwissenschaft – volume: 74 start-page: 174 year: 2007 end-page: 179 ident: bib33 article-title: Cell function in the bovine mammary gland: A preliminary study on interdependence of healthy and infected udder quarters publication-title: J. Dairy Res. – volume: 17 year: 2023 ident: bib34 article-title: Risk factors of high somatic cell count and differential somatic cells in early lactation associated with selective dry cow therapy publication-title: Animal – volume: 61 start-page: 612 year: 2016 end-page: 622 ident: bib59 article-title: Fluorescence microscopy methods for the determination of somatic cell count in raw cow's milk publication-title: Vet. Med. (Praha) – volume: 103 start-page: 572 year: 2020 end-page: 582 ident: bib31 article-title: Analysis of milk leukocyte differential measures for use in management practices for decreased mastitis incidence publication-title: J. Dairy Sci. – volume: 104 start-page: 10934 year: 2021 end-page: 10949 ident: bib37 article-title: Genetic parameters of differential somatic cell count, milk composition, and cheese-making traits measured and predicted using spectral data in Holstein cows publication-title: J. Dairy Sci. – volume: 100 start-page: 4926 year: 2017 end-page: 4940 ident: bib14 article-title: Differential somatic cell count—A novel method for routine mastitis screening in the frame of Dairy Herd Improvement testing programs publication-title: J. Dairy Sci. – volume: 19 start-page: 697 year: 2020 end-page: 703 ident: bib7 article-title: Combining total and differential somatic cell count to better assess the association of udder health status with milk yield, composition and coagulation properties in cattle publication-title: Ital. J. Anim. Sci. – volume: 47 start-page: 663 year: 1986 end-page: 668 ident: bib9 article-title: In vitro study of polymorphonuclear leukocyte damage to mammary tissues of lactating cows publication-title: Am. J. Vet. Res. – volume: 73 start-page: 215 year: 2007 end-page: 220 ident: bib58 article-title: The baseline ratio of neutrophils to lymphocytes is associated with patient prognosis in advanced gastric cancer publication-title: Oncology – volume: 11 start-page: 562 year: 2018 end-page: 577 ident: bib2 article-title: Milk somatic cells, factors influencing their release, future prospects, and practical utility in dairy animals: An overview publication-title: Vet. World – volume: 94 start-page: 1873 year: 2011 end-page: 1892 ident: bib42 article-title: Decision tree analysis of treatment strategies for milk and moderate case of clinical mastitis occurring in early lactation publication-title: J. Dairy Sci. – volume: 47 start-page: 39 year: 1980 end-page: 50 ident: bib29 article-title: Identification, properties, and differential counts of cell populations using electron microscopy of dry cows secretions, colostrum and milk from normal cows publication-title: J. Dairy Res. – volume: 103 start-page: 3838 year: 2020 end-page: 3845 ident: bib16 article-title: Symposium review: Why revisit dairy cattle productive lifespan? publication-title: J. Dairy Sci. – volume: 14 year: 2024 ident: bib17 article-title: Distinctive features and prognostic utility of neutrophil in severe patients with Klebsiella pneumoniae infection publication-title: Front. Cell. Infect. Microbiol. – volume: 107 start-page: 3157 year: 2024 end-page: 3167 ident: bib23 article-title: Intramammary infections in lactating Jersey cows: Prevalence of microbial organisms and association with milk somatic cell count and persistence of infection publication-title: J. Dairy Sci. – volume: 92 start-page: 1941 year: 2009 ident: 10.3168/jds.2025-26945_bib8 article-title: Factors affecting cure when treating bovine clinical mastitis with cephalosporin-based intramammary preparations publication-title: J. Dairy Sci. doi: 10.3168/jds.2008-1497 – volume: 5 start-page: 273 year: 2018 ident: 10.3168/jds.2025-26945_bib47 article-title: Assessing financial impacts of subclinical mastitis on Colombian dairy farms publication-title: Front. Vet. Sci. doi: 10.3389/fvets.2018.00273 – volume: 10 year: 2020 ident: 10.3168/jds.2025-26945_bib11 article-title: Epidemiology and classification of mastitis publication-title: Animals (Basel) – volume: 100 start-page: 4926 year: 2017 ident: 10.3168/jds.2025-26945_bib14 article-title: Differential somatic cell count—A novel method for routine mastitis screening in the frame of Dairy Herd Improvement testing programs publication-title: J. Dairy Sci. doi: 10.3168/jds.2016-12409 – volume: 10 start-page: 7991 year: 2010 ident: 10.3168/jds.2025-26945_bib25 article-title: Sensors and clinical mastitis–the quest for the perfect alert publication-title: Sensors (Basel) doi: 10.3390/s100907991 – volume: 83 start-page: 300 year: 2000 ident: 10.3168/jds.2025-26945_bib26 article-title: Correlation between bovine milk somatic cell count and polymorphonuclear leukocyte level for samples of bulk milk and milk from individual cows publication-title: J. Dairy Sci. doi: 10.3168/jds.S0022-0302(00)74878-8 – volume: 95 start-page: 4410 year: 2012 ident: 10.3168/jds.2025-26945_bib40 article-title: Microscopic differential cell counting to identify inflammatory reactions in dairy cow quarter milk samples publication-title: J. Dairy Sci. doi: 10.3168/jds.2012-5331 – volume: 101 start-page: 5362 year: 2018 ident: 10.3168/jds.2025-26945_bib55 article-title: Differential somatic cell count in milk before, during, and after lipopolysaccharide- and lipoteichoic-acid-induced mastitis in dairy cows publication-title: J. Dairy Sci. doi: 10.3168/jds.2017-14152 – volume: 94 start-page: 1873 year: 2011 ident: 10.3168/jds.2025-26945_bib42 article-title: Decision tree analysis of treatment strategies for milk and moderate case of clinical mastitis occurring in early lactation publication-title: J. Dairy Sci. doi: 10.3168/jds.2010-3930 – volume: 73 start-page: 215 year: 2007 ident: 10.3168/jds.2025-26945_bib58 article-title: The baseline ratio of neutrophils to lymphocytes is associated with patient prognosis in advanced gastric cancer publication-title: Oncology doi: 10.1159/000127412 – volume: 11 start-page: 562 year: 2018 ident: 10.3168/jds.2025-26945_bib2 article-title: Milk somatic cells, factors influencing their release, future prospects, and practical utility in dairy animals: An overview publication-title: Vet. World doi: 10.14202/vetworld.2018.562-577 – volume: 130 start-page: 199 year: 1957 ident: 10.3168/jds.2025-26945_bib48 article-title: Experiments and observations leading to development of the California mastitis test publication-title: J. Am. Vet. Med. Assoc. – volume: 102 start-page: 4275 year: 2019 ident: 10.3168/jds.2025-26945_bib6 article-title: Short communication: Genetic aspects of milk differential somatic cell count in Holstein cows: A preliminary analysis publication-title: J. Dairy Sci. doi: 10.3168/jds.2018-16092 – volume: 13 start-page: 399 year: 2001 ident: 10.3168/jds.2025-26945_bib44 article-title: Longitudinal evaluation of bovine mammary gland health status by somatic cell counting, flow cytometry, and cytology publication-title: J. Vet. Diagn. Invest. doi: 10.1177/104063870101300506 – volume: 12 year: 2022 ident: 10.3168/jds.2025-26945_bib57 article-title: Association of milk somatic cell count with bacteriological cure of intramammary infection—A review publication-title: Agriculture doi: 10.3390/agriculture12091437 – volume: 579 year: 2024 ident: 10.3168/jds.2025-26945_bib24 article-title: Using registry data to identify individual dairy cows with abnormal patterns in routinely recorded somatic cell counts publication-title: J. Theor. Biol. doi: 10.1016/j.jtbi.2023.111718 – volume: 122 start-page: 257 year: 2015 ident: 10.3168/jds.2025-26945_bib46 article-title: The cost of clinical mastitis in the first 30 days of lactation: An economic modeling tool publication-title: Prev. Vet. Med. doi: 10.1016/j.prevetmed.2015.11.006 – volume: 17 year: 2022 ident: 10.3168/jds.2025-26945_bib13 article-title: Relationship between total and differential quarter somatic cell counts at dry-off and early lactation publication-title: PLoS One doi: 10.1371/journal.pone.0275755 – volume: 106 start-page: 9276 year: 2023 ident: 10.3168/jds.2025-26945_bib30 article-title: Variation in partial direct costs of treating clinical mastitis among 37 Wisconsin dairy farms publication-title: J. Dairy Sci. doi: 10.3168/jds.2023-23388 – volume: 107 start-page: 3157 year: 2024 ident: 10.3168/jds.2025-26945_bib23 article-title: Intramammary infections in lactating Jersey cows: Prevalence of microbial organisms and association with milk somatic cell count and persistence of infection publication-title: J. Dairy Sci. doi: 10.3168/jds.2023-23848 – volume: 106 start-page: 9071 year: 2023 ident: 10.3168/jds.2025-26945_bib1 article-title: Heritability and genetic correlations of total and differential somatic cell count with milk yield and composition traits in Italian Simmental cows publication-title: J. Dairy Sci. doi: 10.3168/jds.2023-23639 – volume: 95 start-page: 1025 year: 2012 ident: 10.3168/jds.2025-26945_bib15 article-title: Invited review: Mastitis in dairy heifers: nature of the disease, potential impact, prevention, and control publication-title: J. Dairy Sci. doi: 10.3168/jds.2010-4074 – volume: 181 year: 2020 ident: 10.3168/jds.2025-26945_bib50 article-title: Evaluation of the new differential somatic cell count parameter as a rapid and inexpensive supplementary tool for udder health management through regular milk recording publication-title: Prev. Vet. Med. doi: 10.1016/j.prevetmed.2020.105079 – ident: 10.3168/jds.2025-26945_bib56 – volume: 63 start-page: 235 year: 2010 ident: 10.3168/jds.2025-26945_bib32 article-title: Accurate and rapid flow cytometric leukocyte differentiation in low and high somatic cell count milk publication-title: Milchwissenschaft – volume: 107 start-page: 6945 year: 2024 ident: 10.3168/jds.2025-26945_bib43 article-title: Global losses due to dairy cattle diseases: A comorbidity-adjusted economic analysis publication-title: J. Dairy Sci. doi: 10.3168/jds.2023-24626 – volume: 19 start-page: 697 year: 2020 ident: 10.3168/jds.2025-26945_bib7 article-title: Combining total and differential somatic cell count to better assess the association of udder health status with milk yield, composition and coagulation properties in cattle publication-title: Ital. J. Anim. Sci. doi: 10.1080/1828051X.2020.1784804 – volume: 74 start-page: 174 year: 2007 ident: 10.3168/jds.2025-26945_bib33 article-title: Cell function in the bovine mammary gland: A preliminary study on interdependence of healthy and infected udder quarters publication-title: J. Dairy Res. doi: 10.1017/S002202990600238X – volume: 34 start-page: 507 year: 2018 ident: 10.3168/jds.2025-26945_bib51 article-title: Mammary gland immunobiology and resistance to mastitis publication-title: Vet. Clin. North Am. Food Anim. Pract. doi: 10.1016/j.cvfa.2018.07.005 – volume: 13 year: 2023 ident: 10.3168/jds.2025-26945_bib62 article-title: Early milk total and differential cell counts as a diagnostic tool to improve antimicrobial therapy protocols publication-title: Animals (Basel) – volume: 104 start-page: 4942 year: 2021 ident: 10.3168/jds.2025-26945_bib45 article-title: Technical note: Evaluation of a commercial on-farm milk leukocyte differential tester to identify subclinical mastitis cases in dairy cows publication-title: J. Dairy Sci. doi: 10.3168/jds.2020-19299 – volume: 15 year: 2024 ident: 10.3168/jds.2025-26945_bib20 article-title: Increased neutrophil counts are associated with poor overall survival in patients with colorectal cancer: A five-year retrospective analysis publication-title: Front. Immunol. – volume: 104 start-page: 3427 year: 2021 ident: 10.3168/jds.2025-26945_bib27 article-title: Dynamics of somatic cell count (SCC) and differential SCC during and following intramammary infections publication-title: J. Dairy Sci. doi: 10.3168/jds.2020-19378 – year: 2025 ident: 10.3168/jds.2025-26945_bib54 – volume: 47 start-page: 663 year: 1986 ident: 10.3168/jds.2025-26945_bib9 article-title: In vitro study of polymorphonuclear leukocyte damage to mammary tissues of lactating cows publication-title: Am. J. Vet. Res. doi: 10.2460/ajvr.1986.47.03.663 – volume: 7 year: 2020 ident: 10.3168/jds.2025-26945_bib22 article-title: Differential somatic cell count: Value for udder health management publication-title: Front. Vet. Sci. doi: 10.3389/fvets.2020.609055 – volume: 47 start-page: 39 year: 1980 ident: 10.3168/jds.2025-26945_bib29 article-title: Identification, properties, and differential counts of cell populations using electron microscopy of dry cows secretions, colostrum and milk from normal cows publication-title: J. Dairy Res. doi: 10.1017/S0022029900020860 – volume: 86 start-page: 57 issue: Suppl. 13 year: 2008 ident: 10.3168/jds.2025-26945_bib63 article-title: Mammary tissue damage during bovine mastitis: Causes and control publication-title: J. Anim. Sci. doi: 10.2527/jas.2007-0302 – volume: 61 start-page: 612 year: 2016 ident: 10.3168/jds.2025-26945_bib59 article-title: Fluorescence microscopy methods for the determination of somatic cell count in raw cow's milk publication-title: Vet. Med. (Praha) doi: 10.17221/222/2015-VETMED – volume: 87 start-page: 10 issue: Suppl. 13 year: 2009 ident: 10.3168/jds.2025-26945_bib4 article-title: Pathogen-dependent induction of cytokines and other soluble inflammatory mediators during intramammary infection of dairy cows publication-title: J. Anim. Sci. doi: 10.2527/jas.2008-1187 – volume: 100 start-page: 5592 year: 2017 ident: 10.3168/jds.2025-26945_bib12 article-title: Prevalence of non-aureus staphylococci species causing intramammary infections in Canadian dairy herds publication-title: J. Dairy Sci. doi: 10.3168/jds.2016-12478 – volume: 107 start-page: 11301 year: 2024 ident: 10.3168/jds.2025-26945_bib38 article-title: Genetic evaluation of udder health traits in Spanish Holstein cows publication-title: J. Dairy Sci. doi: 10.3168/jds.2024-25292 – volume: 14 year: 2024 ident: 10.3168/jds.2025-26945_bib17 article-title: Distinctive features and prognostic utility of neutrophil in severe patients with Klebsiella pneumoniae infection publication-title: Front. Cell. Infect. Microbiol. doi: 10.3389/fcimb.2024.1406168 – volume: 103 start-page: 572 year: 2020 ident: 10.3168/jds.2025-26945_bib31 article-title: Analysis of milk leukocyte differential measures for use in management practices for decreased mastitis incidence publication-title: J. Dairy Sci. doi: 10.3168/jds.2019-16355 – volume: 103 start-page: 1759 year: 2020 ident: 10.3168/jds.2025-26945_bib28 article-title: Differential somatic cell count as an additional indicator for intramammary infections in dairy cows publication-title: J. Dairy Sci. doi: 10.3168/jds.2019-16523 – volume: 108 start-page: 2721 year: 2025 ident: 10.3168/jds.2025-26945_bib35 article-title: Factors influencing somatic cell count and leukocyte composition in cow milk: A field study publication-title: J. Dairy Sci. doi: 10.3168/jds.2024-25357 – volume: 101 year: 2023 ident: 10.3168/jds.2025-26945_bib53 article-title: Herd and animal factors affect the variability of total and differential somatic cell count in bovine milk publication-title: J. Anim. Sci. doi: 10.1093/jas/skac406 – volume: 104 start-page: 10934 year: 2021 ident: 10.3168/jds.2025-26945_bib37 article-title: Genetic parameters of differential somatic cell count, milk composition, and cheese-making traits measured and predicted using spectral data in Holstein cows publication-title: J. Dairy Sci. doi: 10.3168/jds.2021-20395 – volume: 10 start-page: 604 year: 2020 ident: 10.3168/jds.2025-26945_bib60 article-title: Differential somatic cell count as a marker for changes of milk composition in cows with very low somatic cell count publication-title: Animals (Basel) doi: 10.3390/ani10040604 – volume: 103 start-page: 3838 year: 2020 ident: 10.3168/jds.2025-26945_bib16 article-title: Symposium review: Why revisit dairy cattle productive lifespan? publication-title: J. Dairy Sci. doi: 10.3168/jds.2019-17361 – volume: 108 start-page: 3929 year: 2025 ident: 10.3168/jds.2025-26945_bib18 article-title: Usefulness of differential somatic cell count for udder health monitoring: Diagnostic performance of somatic cell count, and differential somatic cell count for diagnosing of intramammary infections in dairy herds with automated milking systems publication-title: J. Dairy Sci. doi: 10.3168/jds.2024-25404 – volume: 17 year: 2023 ident: 10.3168/jds.2025-26945_bib34 article-title: Risk factors of high somatic cell count and differential somatic cells in early lactation associated with selective dry cow therapy publication-title: Animal doi: 10.1016/j.animal.2023.100982 – ident: 10.3168/jds.2025-26945_bib36 – volume: 7 start-page: 135 year: 2002 ident: 10.3168/jds.2025-26945_bib52 article-title: Mammary gland immunity and mastitis susceptibility publication-title: J. Mammary Gland Biol. Neoplasia doi: 10.1023/A:1020347818725 – volume: 19 start-page: 217 year: 2012 ident: 10.3168/jds.2025-26945_bib3 article-title: Usefulness of the neutrophil-to-lymphocyte ratio in predicting short- and long-term mortality in breast cancer patients publication-title: Ann. Surg. Oncol. doi: 10.1245/s10434-011-1814-0 – volume: 84 start-page: 1413 year: 2001 ident: 10.3168/jds.2025-26945_bib41 article-title: Application of differential inflammatory cell count as a tool to monitor udder health publication-title: J. Dairy Sci. doi: 10.3168/jds.S0022-0302(01)70173-7 – volume: 94 start-page: 5033 year: 2011 ident: 10.3168/jds.2025-26945_bib49 article-title: Flow cytometric differential cell counts in milk for the evaluation of inflammatory reactions in clinically healthy and subclinically infected bovine mammary glands publication-title: J. Dairy Sci. doi: 10.3168/jds.2011-4348 – volume: 18 start-page: 460 year: 2019 ident: 10.3168/jds.2025-26945_bib61 article-title: Assessment of subclinical mastitis diagnostic accuracy by differential cell count in individual cow milk publication-title: Ital. J. Anim. Sci. doi: 10.1080/1828051X.2018.1533391 – volume: 96 start-page: 1653 year: 2013 ident: 10.3168/jds.2025-26945_bib39 article-title: Differential cell count as an alternative method to diagnose dairy cow mastitis publication-title: J. Dairy Sci. doi: 10.3168/jds.2012-6298 – volume: 100 start-page: 6527 year: 2017 ident: 10.3168/jds.2025-26945_bib21 article-title: Evaluation of an automated milk leukocyte differential test and the California Mastitis Test for detecting intramammary infection in early- and late-lactation quarters and cows publication-title: J. Dairy Sci. doi: 10.3168/jds.2017-12548 – volume: 11 start-page: 463 year: 2004 ident: 10.3168/jds.2025-26945_bib5 article-title: Escherichia coli and Staphylococcus aureus elicit differential innate immune responses following intramammary infection publication-title: Clin. Vaccine Immunol. doi: 10.1128/CDLI.11.3.463-472.2004 – volume: 39 start-page: 76 year: 2019 ident: 10.3168/jds.2025-26945_bib10 article-title: Technological interventions and advances in the diagnosis of intramammary infections in animals with emphasis on bovine population-a review publication-title: Vet. Q. doi: 10.1080/01652176.2019.1642546 – volume: 107 start-page: 3813 year: 2024 ident: 10.3168/jds.2025-26945_bib19 article-title: Frequency of non-aureus staphylococci and mammaliicocci species isolated from quarter clinical mastitis: A 6-year retrospective study publication-title: J. Dairy Sci. doi: 10.3168/jds.2023-24086 |
| SSID | ssj0021205 |
| Score | 2.484986 |
| SecondaryResourceType | review_article |
| Snippet | The list of standard abbreviations for JDS is available at adsa.org/jds-abbreviations-24. Nonstandard abbreviations are available in the Notes.
Mastitis... Mastitis remains a substantial challenge for the dairy industry. Producers strive to maximize dairy cow production, health, and well-being, while also reducing... |
| SourceID | doaj proquest pubmed crossref elsevier |
| SourceType | Open Website Aggregation Database Index Database Publisher |
| StartPage | 13621 |
| SubjectTerms | Animals Cattle Cell Count - veterinary dairy cow Female intramammary infection Mastitis, Bovine - diagnosis Milk - cytology neutrophils somatic cell count |
| Title | Graduate Student Literature Review: Utilization of differential somatic cell count in the detection and management of mastitis |
| URI | https://dx.doi.org/10.3168/jds.2025-26945 https://www.ncbi.nlm.nih.gov/pubmed/41130392 https://www.proquest.com/docview/3264651642 https://doaj.org/article/9c5f2c438a8e44659f9def38ba8bc4a1 |
| Volume | 108 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1525-3198 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0021205 issn: 0022-0302 databaseCode: DOA dateStart: 20220101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Nb9QwEB1BxQEOiG-2QGUkJE5RE9tZ29wKonBAFRJU2pvljzFa1GbRfnDkt9djJ6tyqLiQYxQ5lt84fhM_vwF4o6R22LWGNt1DTlA62bh5Uk1EKUSK-ep9KTahzs70YmG-Xiv1RZqwag9cB-7YhD7xIIV2GsncyyQTMQntnfZBupL4tMpMydSYanW8ihdJq57DmFe7RirSdPwzkks3J22XoUNM15aj4tr_16p0E-ssq8_pA7g_0kZ2Urv7EG7h8AjunfxYj9YZ-Bj-fFq7uMvUkX2rfpXsy94ymdUtgHfsfLu8GE9eslViU3mUPM0v2GZV7FsZ_ctnpYYEWw4sE0QWcVsUWwNzQ2SXe8UMNXHpSG2w3DyB89OP3z98bsbqCk2gSdx0IproNJdeyV7xZEQIc-_jPHZBtaglRt9iwi5pbXqfuA885K-Bxz7fFUE8hYNhNeBzYCZzAi-80iH0MpngtHO-161JUjnE-QzeToNsf1UTDZuTD4LDZjgswWELHDN4TxjsnyLz63Ijh4QdQ8L-KyRm0E0I2pFHVH6Qm1re-OLXE9Q2TzAaaTfgarexmd9Svficp83gWY2BffdkRxTA8MP_0e0XcLfEZdHKvISD7XqHr-BO-J0xXB_BbbXQRyXKrwCQdgL1 |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Graduate+Student+Literature+Review%3A+Utilization+of+differential+somatic+cell+count+in+the+detection+and+management+of+mastitis&rft.jtitle=Journal+of+dairy+science&rft.au=Carmen+Burner&rft.au=Todd+R.+Callaway&rft.au=Valerie+E.+Ryman&rft.date=2025-12-01&rft.pub=Elsevier&rft.issn=0022-0302&rft.volume=108&rft.issue=12&rft.spage=13621&rft.epage=13630&rft_id=info:doi/10.3168%2Fjds.2025-26945&rft.externalDBID=DOA&rft.externalDocID=oai_doaj_org_article_9c5f2c438a8e44659f9def38ba8bc4a1 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-0302&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-0302&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-0302&client=summon |