Reassortant Cache Valley Virus Associated With Acute Febrile, Nonneurologic Illness, Missouri

An adult male from Missouri sought care for fever, fatigue, and gastrointestinal symptoms. He had leukopenia and thrombocytopenia and was treated for a presumed tickborne illness. His condition deteriorated with respiratory and renal failure, lactic acidosis, and hypotension. Next-generation sequenc...

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Published in:Clinical infectious diseases Vol. 73; no. 9; p. 1700
Main Authors: Baker, Molly, Hughes, Holly R, Naqvi, S Hasan, Yates, Karen, Velez, Jason O, McGuirk, Sophia, Schroder, Barb, Lambert, Amy J, Kosoy, Olga I, Pue, Howard, Turabelidze, George, Staples, J Erin
Format: Journal Article
Language:English
Published: United States 02.11.2021
Subjects:
Adult
Bunyamwera virus
Bunyaviridae Infections - diagnosis
Bunyaviridae Infections - epidemiology
Fever
Humans
Male
Missouri - epidemiology
Phylogeny
Missouri
Orthobunyavirus
Bunyamwera group viruses
reassortant virus
next-generation sequencing
Cache Valley virus
ISSN:1537-6591, 1537-6591
Online Access:Get more information
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Abstract An adult male from Missouri sought care for fever, fatigue, and gastrointestinal symptoms. He had leukopenia and thrombocytopenia and was treated for a presumed tickborne illness. His condition deteriorated with respiratory and renal failure, lactic acidosis, and hypotension. Next-generation sequencing and phylogenetic analysis identified a reassortant Cache Valley virus.
AbstractList An adult male from Missouri sought care for fever, fatigue, and gastrointestinal symptoms. He had leukopenia and thrombocytopenia and was treated for a presumed tickborne illness. His condition deteriorated with respiratory and renal failure, lactic acidosis, and hypotension. Next-generation sequencing and phylogenetic analysis identified a reassortant Cache Valley virus.An adult male from Missouri sought care for fever, fatigue, and gastrointestinal symptoms. He had leukopenia and thrombocytopenia and was treated for a presumed tickborne illness. His condition deteriorated with respiratory and renal failure, lactic acidosis, and hypotension. Next-generation sequencing and phylogenetic analysis identified a reassortant Cache Valley virus.
An adult male from Missouri sought care for fever, fatigue, and gastrointestinal symptoms. He had leukopenia and thrombocytopenia and was treated for a presumed tickborne illness. His condition deteriorated with respiratory and renal failure, lactic acidosis, and hypotension. Next-generation sequencing and phylogenetic analysis identified a reassortant Cache Valley virus.
Author Baker, Molly
Velez, Jason O
Schroder, Barb
Hughes, Holly R
Yates, Karen
Pue, Howard
McGuirk, Sophia
Lambert, Amy J
Naqvi, S Hasan
Kosoy, Olga I
Turabelidze, George
Staples, J Erin
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  organization: Missouri Department of Health and Senior Services, Jefferson City and St Louis, Missouri, USA
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  givenname: Holly R
  surname: Hughes
  fullname: Hughes, Holly R
  organization: Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA
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  givenname: S Hasan
  surname: Naqvi
  fullname: Naqvi, S Hasan
  organization: University of Missouri School of Medicine, Columbia, Missouri, USA
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  givenname: Karen
  surname: Yates
  fullname: Yates, Karen
  organization: Missouri Department of Health and Senior Services, Jefferson City and St Louis, Missouri, USA
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  givenname: Jason O
  surname: Velez
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  organization: Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA
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  organization: University of Missouri School of Medicine, Columbia, Missouri, USA
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  organization: Missouri Department of Health and Senior Services, Jefferson City and St Louis, Missouri, USA
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  fullname: Lambert, Amy J
  organization: Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA
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  givenname: Olga I
  surname: Kosoy
  fullname: Kosoy, Olga I
  organization: Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA
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  surname: Pue
  fullname: Pue, Howard
  organization: Missouri Department of Health and Senior Services, Jefferson City and St Louis, Missouri, USA
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  organization: Missouri Department of Health and Senior Services, Jefferson City and St Louis, Missouri, USA
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  givenname: J Erin
  surname: Staples
  fullname: Staples, J Erin
  organization: Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA
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Issue 9
Keywords Orthobunyavirus
Bunyamwera group viruses
reassortant virus
next-generation sequencing
Cache Valley virus
Language English
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Snippet An adult male from Missouri sought care for fever, fatigue, and gastrointestinal symptoms. He had leukopenia and thrombocytopenia and was treated for a...
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SubjectTerms Adult
Bunyamwera virus
Bunyaviridae Infections - diagnosis
Bunyaviridae Infections - epidemiology
Fever
Humans
Male
Missouri - epidemiology
Phylogeny
Title Reassortant Cache Valley Virus Associated With Acute Febrile, Nonneurologic Illness, Missouri
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