Total bodyweight and sex both drive pharmacokinetic variability of fluconazole in obese adults

Fluconazole is commonly used to treat or prevent fungal infections. It is typically used orally but in critical situations, IV administration is needed. Obesity may influence the pharmacokinetics and therapeutic efficacy of a drug. In this study, we aim to assess the impact of obesity on fluconazole...

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Vydané v:	Journal of antimicrobial chemotherapy Ročník 77; číslo 8; s. 2217
Hlavní autori:	Chen, Lu, van Rhee, Koen P, Wasmann, Roeland E, Krekels, Elke H J, Wiezer, Marinus J, van Dongen, Eric P A, Verweij, Paul E, van der Linden, Paul D, Brüggemann, Roger J, Knibbe, Catherijne A J
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 28.07.2022
ISSN:	1460-2091, 1460-2091
On-line prístup:	Zistit podrobnosti o prístupe
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