Polyadenylation of Sine Transcripts Generated by RNA Polymerase III Dramatically Prolongs Their Lifetime in Cells

— Short Interspersed Elements (SINEs) are mobile genetic elements of higher eukaryotes, which originated during evolution from various tRNAs and less often from 5S rRNA and 7SL RNA. Similar to the genes of these RNAs, SINEs are transcribed by RNA polymerase III. The transcripts of some mammalian SIN...

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Veröffentlicht in:	Molecular biology (New York) Jg. 54; H. 1; S. 67 - 74
Hauptverfasser:	Ustyantsev, I. G., Tatosyan, K. A., Stasenko, D. V., Kochanova, N. Y., Borodulina, O. R., Kramerov, D. A.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Moscow Pleiades Publishing 01.01.2020 Springer Nature B.V
Schlagworte:	Biochemistry Biomedical and Life Sciences Deoxyribonucleic acid DNA DNA-directed RNA polymerase Expression vectors Human Genetics Hybridization Insertion Life Sciences Molecular Cell Biology Poly(A) Poly(A)-binding protein Polyadenylation RNA polymerase rRNA 5S Transcription polyadenylation RNA polymerase III RNA stability noncoding RNA mammals retroposones RNA decay poly(A) SINE
ISSN:	0026-8933, 1608-3245
Online-Zugang:	Volltext
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