A novel 1,3,5-Triazine-based fluorescent probe with large Stokes shift for the detection of Hg(II) and its application in cell, zebrafish and tobacco imaging
[Display omitted] •A fluorescent probe based on 1,3,5-Triazine was designed and synthesized to detect Hg(Ⅱ).•The novel fluorescent probe exhibited high selectivity, good stability, large Stokes shift (100 nm).•The novel fluorescent probe has been successfully used for cell and zebrafish imaging.•The...
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| Veröffentlicht in: | Journal of photochemistry and photobiology. A, Chemistry. Jg. 447; S. 115171 |
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| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
Elsevier B.V
15.01.2024
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| ISSN: | 1010-6030, 1873-2666 |
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| Abstract | [Display omitted]
•A fluorescent probe based on 1,3,5-Triazine was designed and synthesized to detect Hg(Ⅱ).•The novel fluorescent probe exhibited high selectivity, good stability, large Stokes shift (100 nm).•The novel fluorescent probe has been successfully used for cell and zebrafish imaging.•The novel fluorescent probe has successfully detected Hg(II) in tobacco.
Non-biodegradable, bioaccumulative, and highly toxic, mercury(II) poses a significant threat to both ecosystems and human health. Extensive data indicates that even extremely low levels of Hg(II) can cause significant harm to human health. In this paper, the thiocarbonate specific recognition site was used for the detection of Hg(II), which was successfully synthesized by the hydroxyl group of 1,3,5-Triazine with phenyl chlorothiocarbonate. The probe exhibited advantages of high sensitivity (0.253 μM), good selectivity, large Stokes shift (100 nm), and good biocompatibility. The probe TzAr-Nap-Hg successfully fluorescently imaged Hg(II) in cells, zebrafish and tobacco, making it possible to detect the content of Hg(II) in agricultural and sideline products. |
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| AbstractList | [Display omitted]
•A fluorescent probe based on 1,3,5-Triazine was designed and synthesized to detect Hg(Ⅱ).•The novel fluorescent probe exhibited high selectivity, good stability, large Stokes shift (100 nm).•The novel fluorescent probe has been successfully used for cell and zebrafish imaging.•The novel fluorescent probe has successfully detected Hg(II) in tobacco.
Non-biodegradable, bioaccumulative, and highly toxic, mercury(II) poses a significant threat to both ecosystems and human health. Extensive data indicates that even extremely low levels of Hg(II) can cause significant harm to human health. In this paper, the thiocarbonate specific recognition site was used for the detection of Hg(II), which was successfully synthesized by the hydroxyl group of 1,3,5-Triazine with phenyl chlorothiocarbonate. The probe exhibited advantages of high sensitivity (0.253 μM), good selectivity, large Stokes shift (100 nm), and good biocompatibility. The probe TzAr-Nap-Hg successfully fluorescently imaged Hg(II) in cells, zebrafish and tobacco, making it possible to detect the content of Hg(II) in agricultural and sideline products. |
| ArticleNumber | 115171 |
| Author | Li, Lin Wang, Mao-Hua Zhang, Li-Meng Chen, Yun-Feng Chen, Guo-Yu He, Yuan Li, Cong-Cong Wang, Lin-Qing Wang, Jian-Yong |
| Author_xml | – sequence: 1 givenname: Yuan surname: He fullname: He, Yuan email: heyuan818@163.com organization: Collaborative Innovation Center of Food Production and Safety, College of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China – sequence: 2 givenname: Yun-Feng surname: Chen fullname: Chen, Yun-Feng organization: Collaborative Innovation Center of Food Production and Safety, College of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China – sequence: 3 givenname: Cong-Cong surname: Li fullname: Li, Cong-Cong organization: Faculty of Light Industry, Qi Lu University of Technology (Shandong Academy of Science), Jinan 250353, PR China – sequence: 4 givenname: Mao-Hua surname: Wang fullname: Wang, Mao-Hua organization: Faculty of Light Industry, Qi Lu University of Technology (Shandong Academy of Science), Jinan 250353, PR China – sequence: 5 givenname: Lin surname: Li fullname: Li, Lin organization: Zhengzhou Recombinant Antibody Drug Engnieering Technology Center, College of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, PR China – sequence: 6 givenname: Guo-Yu surname: Chen fullname: Chen, Guo-Yu organization: Collaborative Innovation Center of Food Production and Safety, College of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450002, PR China – sequence: 7 givenname: Li-Meng surname: Zhang fullname: Zhang, Li-Meng organization: Zhengzhou Recombinant Antibody Drug Engnieering Technology Center, College of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, PR China – sequence: 8 givenname: Lin-Qing surname: Wang fullname: Wang, Lin-Qing organization: Zhengzhou Recombinant Antibody Drug Engnieering Technology Center, College of Life Sciences, Zhengzhou Normal University, Zhengzhou 450044, PR China – sequence: 9 givenname: Jian-Yong orcidid: 0000-0002-5254-1525 surname: Wang fullname: Wang, Jian-Yong email: wjy@qlu.edu.cn organization: Faculty of Light Industry, Qi Lu University of Technology (Shandong Academy of Science), Jinan 250353, PR China |
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| Keywords | Large Stokes shift Cells imaging Hg(II) Tobacco imaging Zebrafish imaging Fluorescent probe |
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| SubjectTerms | Cells imaging Fluorescent probe Hg(II) Large Stokes shift Tobacco imaging Zebrafish imaging |
| Title | A novel 1,3,5-Triazine-based fluorescent probe with large Stokes shift for the detection of Hg(II) and its application in cell, zebrafish and tobacco imaging |
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