The etiology of clonal mosaicism in human aging and disease

Our DNA is consistently assaulted by a variety of intrinsic and extrinsic mutational factors. Fortunately, DNA repair provides for protective barriers that limit the full manifestation of DNA damage. Yet, DNA repair represents no panacea as DNA damage continuously slips through these erected defense...

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Bibliographic Details
Published in:	Aging and cancer Vol. 4; no. 1; pp. 3 - 20
Main Authors:	Massaar, Sanne, Sanders, Mathijs A.
Format:	Journal Article
Language:	English
Published:	Hoboken John Wiley & Sons, Inc 01.03.2023 Wiley
Subjects:	Age Aging Amino acids Cancer cancer & DNA repair Cell division clonal expansion DNA damage DNA methylation DNA repair Epigenetics Genes Genomes Mutation Radiation somatic mutation Stem cells
ISSN:	2643-8909, 2643-8909
Online Access:	Get full text
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