Time-dependent dual mode of action of COX-2 inhibition on mouse serum corticosterone levels

•Short-term COX-2 inhibition increased corticosterone levels,•Long-term COX-2 inhibition lowered corticosterone levels,•Corticosterone levels are regulated through a COX-2-dependent mechanism in mice. To elucidate the effect of cyclooxygenase-2 (COX-2) inhibition on corticosterone release, mice were...

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Bibliographic Details
Published in:	Steroids Vol. 207; p. 109438
Main Authors:	Pańczyszyn-Trzewik, Patrycja, Sowa-Kućma, Magdalena, Misztak, Paulina, Tabecka-Lonczynska, Anna, Stachowicz, Katarzyna
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.07.2024
Subjects:	Animals Corticosterone Corticosterone - blood COX-2 Cyclooxygenase 2 - blood Cyclooxygenase 2 - metabolism Cyclooxygenase 2 Inhibitors - pharmacology Lipopolysaccharides - pharmacology LPS Male Mice Nitrobenzenes - pharmacology NS398 Sulfonamides - pharmacology Time Factors COX-2 NS398 Corticosterone LPS
ISSN:	0039-128X, 1878-5867, 1878-5867
Online Access:	Get full text
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