Ocular preservation with neoadjuvant vismodegib in patients with locally advanced periocular basal cell carcinoma

Locally advanced (T4 per American Joint Committee on Cancer (AJCC) 8th edition) periocular basal cell carcinoma (BCC) can lead to loss of the eye. We report the neoadjuvant use of vismodegib followed by surgery in patients with such lesions with eye preservation as primary goal. This retrospective i...

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Veröffentlicht in:	British journal of ophthalmology Jg. 103; H. 6; S. 775 - 780
Hauptverfasser:	Sagiv, Oded, Nagarajan, Priyadharsini, Ferrarotto, Renata, Kandl, Thomas J, Thakar, Sudip D, Glisson, Bonnie S, Altan, Mehmet, Esmaeli, Bita
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.06.2019
Schlagworte:	Administration, Oral Aged Aged, 80 and over Anilides - administration & dosage Biopsy Carcinoma, Basal Cell - diagnosis Carcinoma, Basal Cell - therapy Dose-Response Relationship, Drug Eyelid Neoplasms - diagnosis Eyelid Neoplasms - therapy Eyelids - pathology Eyelids - surgery Female Follow-Up Studies Humans Male Middle Aged Neoadjuvant Therapy Neoplasm Staging Ophthalmologic Surgical Procedures - methods Pyridines - administration & dosage Retrospective Studies Treatment Outcome treatment surgery neoplasia treatment medical
ISSN:	0007-1161, 1468-2079, 1468-2079
Online-Zugang:	Volltext
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