Ocular preservation with neoadjuvant vismodegib in patients with locally advanced periocular basal cell carcinoma

Locally advanced (T4 per American Joint Committee on Cancer (AJCC) 8th edition) periocular basal cell carcinoma (BCC) can lead to loss of the eye. We report the neoadjuvant use of vismodegib followed by surgery in patients with such lesions with eye preservation as primary goal. This retrospective i...

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Bibliographic Details
Published in:	British journal of ophthalmology Vol. 103; no. 6; pp. 775 - 780
Main Authors:	Sagiv, Oded, Nagarajan, Priyadharsini, Ferrarotto, Renata, Kandl, Thomas J, Thakar, Sudip D, Glisson, Bonnie S, Altan, Mehmet, Esmaeli, Bita
Format:	Journal Article
Language:	English
Published:	England 01.06.2019
Subjects:	Administration, Oral Aged Aged, 80 and over Anilides - administration & dosage Biopsy Carcinoma, Basal Cell - diagnosis Carcinoma, Basal Cell - therapy Dose-Response Relationship, Drug Eyelid Neoplasms - diagnosis Eyelid Neoplasms - therapy Eyelids - pathology Eyelids - surgery Female Follow-Up Studies Humans Male Middle Aged Neoadjuvant Therapy Neoplasm Staging Ophthalmologic Surgical Procedures - methods Pyridines - administration & dosage Retrospective Studies Treatment Outcome treatment surgery neoplasia treatment medical
ISSN:	0007-1161, 1468-2079, 1468-2079
Online Access:	Get full text
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