Counteracting breast-cancer induced immune suppression by reactivating lymph node-resident conventional dendritic cells (LNR-cDC)

Breast cancer (BrC)-derived factors inhibit proper development and activation of dendritic cells (DC), which in turn promote the expansion of regulatory T cells (Tregs), thus contributing to tumor progression and spread. In two separate BrC sentinel lymph node (SLN) cohorts, one from the EACRI in Po...

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Veröffentlicht in:Journal for immunotherapy of cancer Jg. 3; H. Suppl 2; S. P276
Hauptverfasser: van de Ven, Rieneke, van Pul, Kim, Aliabadi, Shaghayegh, van den Tol, Petrousjka, te Velde, Lisette A, Rutgers, Emiel JTh, Vuylsteke, Ronald JCLM, Stockmann, Hein BAC, Dubay, Christopher, Harrington, Chris, Fox, Bernard A, de Gruijl, Tanja D
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London BioMed Central 04.11.2015
BioMed Central Ltd
BMJ Publishing Group LTD
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ISSN:2051-1426, 2051-1426
Online-Zugang:Volltext
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