Counteracting breast-cancer induced immune suppression by reactivating lymph node-resident conventional dendritic cells (LNR-cDC)

Breast cancer (BrC)-derived factors inhibit proper development and activation of dendritic cells (DC), which in turn promote the expansion of regulatory T cells (Tregs), thus contributing to tumor progression and spread. In two separate BrC sentinel lymph node (SLN) cohorts, one from the EACRI in Po...

Full description

Saved in:

Bibliographic Details
Published in:	Journal for immunotherapy of cancer Vol. 3; no. Suppl 2; p. P276
Main Authors:	van de Ven, Rieneke, van Pul, Kim, Aliabadi, Shaghayegh, van den Tol, Petrousjka, te Velde, Lisette A, Rutgers, Emiel JTh, Vuylsteke, Ronald JCLM, Stockmann, Hein BAC, Dubay, Christopher, Harrington, Chris, Fox, Bernard A, de Gruijl, Tanja D
Format:	Journal Article
Language:	English
Published:	London BioMed Central 04.11.2015 BioMed Central Ltd BMJ Publishing Group LTD
Subjects:	Antigens Breast cancer Complications and side effects Health aspects Immunology Immunosuppression Immunotherapy Lymph nodes Lymphatic system Lymphocytes Medicine Medicine & Public Health Metastasis Oncology Poster Presentation Prevention Sentinel Lymph Node Treg Frequency Efficient Antigen Immune Suppression Dendritic Cell
ISSN:	2051-1426, 2051-1426
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!