Relevant Ongoing Clinical Trials to Investigate Local‐Regional Treatment Strategies for Peritoneal Surface Malignancies

ABSTRACT Background and Objectives The multimodal therapy of peritoneal metastases of common cancers (i.e. colorectal, gastric, and ovarian), including CRS plus HIPEC, is still subject to several clinical studies. Methods This paper presents the ongoing studies regarding HIPEC, as found on clinicalt...

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Vydáno v:Journal of surgical oncology Ročník 130; číslo 6; s. 1349 - 1357
Hlavní autoři: Blaj, S., Häusler, S., Piso, P.
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Wiley Subscription Services, Inc 01.11.2024
Témata:
Chemotherapy, Cancer, Regional Perfusion
Clinical Trials as Topic
Clinical Trials, Phase III as Topic
Combined Modality Therapy
Cytoreduction Surgical Procedures
cytoreductive surgery
Humans
Hyperthermia, Induced
Hyperthermic Intraperitoneal Chemotherapy
ongoing studies
Peritoneal Neoplasms - secondary
Peritoneal Neoplasms - therapy
Stomach Neoplasms - pathology
ongoing studies
hyperthermic intraperitoneal chemotherapy
cytoreductive surgery
ISSN:0022-4790, 1096-9098, 1096-9098
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Shrnutí:ABSTRACT Background and Objectives The multimodal therapy of peritoneal metastases of common cancers (i.e. colorectal, gastric, and ovarian), including CRS plus HIPEC, is still subject to several clinical studies. Methods This paper presents the ongoing studies regarding HIPEC, as found on clinicaltrials.gov. The emphasis was set on Phase III recruiting trials, including the newest information from principal investigators who answered the call of the authors. Results Ninety trials have been identified, and the protocols of 15 studies have been presented in detail. Conclusions There are interesting ongoing trials investigating the role of CRS plus HIPEC.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ObjectType-Review-3
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ISSN:0022-4790
1096-9098
1096-9098
DOI:10.1002/jso.27853