Dopamine disruption and autism phenotypes in slc6a3−/− zebrafish: Behavioural and molecular insights

Dopamine plays a crucial role in regulating movement, motivation, attention, and emotions. Disruptions in dopamine metabolism have been linked to various psychiatric disorders, including autism spectrum disorder (ASD). In this study, we generated an slc6a3 knockout zebrafish model using the CRISPR-C...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Progress in neuro-psychopharmacology & biological psychiatry Ročník 143; s. 111528
Hlavní autori:	Li, Wen, Zhang, Xiaocong, Niu, Xiaoyu, Qin, Nan, Kang, Lulu, Wang, Kai, Wang, Mingyong
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Elsevier Inc 20.12.2025
Predmet:	Autism spectrum disorder Behavioural analysis Dopamine dysfunction slc6a3 Zebrafish model AB mpf slc6a3 Behavioural analysis ARRIVE KO Zebrafish model HPLC-ECD IHC Autism spectrum disorder SD RNA-seq TH ANOVA Dopamine dysfunction IACUC qPCR SEM dpf DA ELISA ISH
ISSN:	0278-5846, 1878-4216, 1878-4216
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!