Iontronic Neuromorphic Signaling with Conical Microfluidic Memristors

Experiments have shown that the conductance of conical channels, filled with an aqueous electrolyte, can strongly depend on the history of the applied voltage. These channels hence have a memory and are promising elements in brain-inspired (iontronic) circuits. We show here that the memory of such c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Physical review letters Jg. 130; H. 26; S. 268401
Hauptverfasser: Kamsma, T. M., Boon, W. Q., ter Rele, T., Spitoni, C., van Roij, R.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 30.06.2023
Schlagworte:
Action Potentials - physiology
Microfluidics
Neurons
Potassium Channels
Signal Transduction
ISSN:0031-9007, 1079-7114, 1079-7114
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Experiments have shown that the conductance of conical channels, filled with an aqueous electrolyte, can strongly depend on the history of the applied voltage. These channels hence have a memory and are promising elements in brain-inspired (iontronic) circuits. We show here that the memory of such channels stems from transient concentration polarization over the ionic diffusion time. We derive an analytic approximation for these dynamics which shows good agreement with full finite-element calculations. Using our analytic approximation, we propose an experimentally realizable Hodgkin-Huxley iontronic circuit where micrometer cones take on the role of sodium and potassium channels. Our proposed circuit exhibits key features of neuronal communication such as all-or-none action potentials upon a pulse stimulus and a spike train upon a sustained stimulus.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0031-9007
1079-7114
1079-7114
DOI:10.1103/PhysRevLett.130.268401