Imaging tumour heterogeneity of the consequences of a PKCα-substrate interaction in breast cancer patients

Breast cancer heterogeneity demands that prognostic models must be biologically driven and recent clinical evidence indicates that future prognostic signatures need evaluation in the context of early compared with late metastatic risk prediction. In pre-clinical studies, we and others have shown tha...

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Vydáno v:	Biochemical Society transactions Ročník 42; číslo 6; s. 1498
Hlavní autoři:	Weitsman, Gregory, Lawler, Katherine, Kelleher, Muireann T, Barrett, James E, Barber, Paul R, Shamil, Eamon, Festy, Frederic, Patel, Gargi, Fruhwirth, Gilbert O, Huang, Lufei, Tullis, Iain D C, Woodman, Natalie, Ofo, Enyinnaya, Ameer-Beg, Simon M, Irshad, Sheeba, Condeelis, John, Gillett, Cheryl E, Ellis, Paul A, Vojnovic, Borivoj, Coolen, Anthony C C, Ng, Tony
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England 01.12.2014
Témata:	Actin Depolymerizing Factors - metabolism Breast Neoplasms - enzymology Breast Neoplasms - metabolism Breast Neoplasms - pathology Cytoskeletal Proteins - metabolism Female Fluorescence Resonance Energy Transfer Humans Neoplasm Metastasis Phosphorylation Protein Kinase C-alpha - metabolism Subcellular Fractions - metabolism Substrate Specificity Treatment Outcome
ISSN:	1470-8752, 1470-8752
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