Noninvasive molecular screening for oral precancer in Fanconi anemia patients

LOH at chromosome arms 3p, 9p, 11q, and 17p are well-established oncogenetic aberrations in oral precancerous lesions and promising biomarkers to monitor the development of oral cancer. Noninvasive LOH screening of brushed oral cells is a preferable method for precancer detection in patients at incr...

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Bibliographic Details
Published in:	Cancer prevention research (Philadelphia, Pa.) Vol. 8; no. 11; p. 1102
Main Authors:	Smetsers, Stephanie E, Velleuer, Eunike, Dietrich, Ralf, Wu, Thijs, Brink, Arjen, Buijze, Marijke, Deeg, Dorly J H, Soulier, Jean, Leemans, C René, Braakhuis, Boudewijn J M, Brakenhoff, Ruud H
Format:	Journal Article
Language:	English
Published:	United States 01.11.2015
Subjects:	Adult Aged Aged, 80 and over Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - genetics Cross-Sectional Studies Early Detection of Cancer - methods Fanconi Anemia - complications Female Head and Neck Neoplasms - diagnosis Head and Neck Neoplasms - genetics Humans Leukocyte Common Antigens - metabolism Loss of Heterozygosity Male Microsatellite Repeats - genetics Middle Aged Mouth Neoplasms - complications Mouth Neoplasms - diagnosis Mouth Neoplasms - genetics Precancerous Conditions - complications Precancerous Conditions - diagnosis Precancerous Conditions - genetics Prevalence Squamous Cell Carcinoma of Head and Neck
ISSN:	1940-6215, 1940-6215
Online Access:	Get more information
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