(Non-)translational medicine: targeting bacterial RNA

The rise and spread of antibiotic resistance is among the most severe challenges facing modern medicine. Despite this fact, attempts to develop novel classes of antibiotic have been largely unsuccessful. The traditional mechanisms by which antibiotics work are subject to relatively rapid bacterial r...

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Bibliographic Details

Published in:	Frontiers in genetics Vol. 4; p. 230
Main Authors:	Dinan, Adam M., Loftus, Brendan J.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 2013
Subjects:	Genetics riboswitch bacteria locked nucleic acids non-coding RNA small RNA antibiotics antisense external guide sequence
ISSN:	1664-8021, 1664-8021
Online Access:	Get full text
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