HBx-Induced HSPA8 Stimulates HBV Replication and Suppresses Ferroptosis to Support Liver Cancer Progression

Hepatitis B virus (HBV) infection is a major driver of hepatocarcinogenesis. Ferroptosis is a type of iron-mediated cell death that can suppress liver transformation. Previous studies have linked HBV to ferroptosis in liver fibrosis and acute liver failure. However, whether ferroptosis is involved i...

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Bibliographic Details

Published in:	Cancer research (Chicago, Ill.) Vol. 83; no. 7; p. 1048
Main Authors:	Wang, Yufei, Zhao, Man, Zhao, Lina, Geng, Yu, Li, Guanghao, Chen, Lin, Yu, Jingxuan, Yuan, Hongfeng, Zhang, Huihui, Yun, Haolin, Yuan, Ying, Wang, Guowen, Feng, Jinyan, Xu, Liang, Wang, Shuai, Hou, Chunyu, Yang, Guang, Zhang, Ningning, Lu, Wei, Zhang, Xiaodong
Format:	Journal Article
Language:	English
Published:	United States 04.04.2023
Subjects:	DNA, Circular - metabolism Ferroptosis Hep G2 Cells Hepatitis B - complications Hepatitis B virus - genetics Hepatitis B virus - metabolism HSC70 Heat-Shock Proteins - genetics HSC70 Heat-Shock Proteins - metabolism Humans Liver Neoplasms - genetics Virus Replication - genetics
ISSN:	1538-7445, 1538-7445
Online Access:	Get more information
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