Inhibition of MicroRNA-494 Reduces Carotid Artery Atherosclerotic Lesion Development and Increases Plaque Stability

Unstable atherosclerotic lesions in carotid arteries require surgical endarterectomy to reduce the risk of ischemic stroke. We aimed to identify microRNAs that exert a broad effect on atherosclerotic plaque formation and stability in the carotid artery. We made a selection of 164 genes involved in a...

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Vydané v:	Annals of surgery Ročník 262; číslo 5; s. 841 - 7; discussion 847-8
Hlavní autori:	Wezel, Anouk, Welten, Sabine M J, Razawy, Wida, Lagraauw, H Maxime, de Vries, Margreet R, Goossens, Eveline A C, Boonstra, Martin C, Hamming, Jaap F, Kandimalla, Ekambar R, Kuiper, Johan, Quax, Paul H A, Nossent, A Yaël, Bot, Ilze
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.11.2015
Predmet:	Animals Atherosclerosis - genetics Atherosclerosis - metabolism Blotting, Western Carotid Arteries Disease Models, Animal DNA - genetics Gene Expression Regulation Humans Male Mice MicroRNAs - biosynthesis MicroRNAs - genetics Plaque, Atherosclerotic - genetics Plaque, Atherosclerotic - metabolism Reverse Transcriptase Polymerase Chain Reaction
ISSN:	1528-1140
On-line prístup:	Zistit podrobnosti o prístupe
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