The complexity of recognition of ubiquitinated substrates by the 26S proteasome

The Ubiquitin Proteasome System (UPS) was discovered in two steps. Initially, APF-1 (ATP-dependent proteolytic Factor 1) later identified as ubiquitin (Ub), a hitherto known protein of unknown function, was found to covalently modify proteins. This modification led to degradation of the tagged prote...

Celý popis

Podrobná bibliografie

Vydáno v:	Biochimica et biophysica acta Ročník 1843; číslo 1; s. 86 - 96
Hlavní autoři:	Ciechanover, Aaron, Stanhill, Ariel
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Netherlands 01.01.2014
Témata:	Animals Binding Sites Humans Models, Molecular Polyubiquitin - chemistry Polyubiquitin - metabolism Proteasome Endopeptidase Complex - metabolism Protein Binding Protein Sorting Signals - physiology Proteolysis Substrate Specificity Ubiquitinated Proteins - chemistry Ubiquitinated Proteins - metabolism Ubiquitin 26S proteasome
ISSN:	0167-4889, 0006-3002
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!