Metal-organic framework nanoagent induces cuproptosis for effective immunotherapy of malignant glioblastoma

Glioblastoma (GBM) is an aggressive brain cancer with an immunosuppressive tumor microenvironment. Here, a copper-based nanoplatform BSO-CAT@MOF-199 @DDM (BCMD) is constructed for mediating cuproptosis and subsequently promoting immunotherapy of glioblastoma. Specifically, BCMD can be degraded in th...

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Bibliographic Details

Published in:	Nano today Vol. 51; p. 101911
Main Authors:	Huang, Qian-Xiao, Liang, Jun-Long, Chen, Qi-Wen, Jin, Xiao-Kang, Niu, Mei-Ting, Dong, Cheng-Yuan, Zhang, Xian-Zheng
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 01.08.2023
Subjects:	Cuproptosis Ferredoxin Glioblastoma Immunogenic cell death Intranasal administration Intranasal administration Ferredoxin Cuproptosis Immunogenic cell death Glioblastoma
ISSN:	1748-0132, 1878-044X
Online Access:	Get full text
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