Whole-body MRI for metastases screening: a preliminary study using 3D VIBE sequences with automatic subtraction between noncontrast and contrast enhanced images

To evaluate 3D Volumetric Interpolated Breath-hold Examination (VIBE) whole-body MRI (WB-MRI) acquisition for the metastases staging. Thirty-two consecutive patients with solid tumor were examined from head to feet before and after contrast injection. An automatic subtraction occurred between the 2...

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Vydáno v:	American journal of clinical oncology Ročník 31; číslo 3; s. 285
Hlavní autoři:	Thomson, Vivien, Pialat, Jean-Baptiste, Gay, Frédéric, Coulon, Agnès, Voloch, Alain, Granier, Anne, Guérin, Jean-Claude, Viallon, Magalie, Berthezene, Yves
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.06.2008
Témata:	Adrenal Gland Neoplasms - diagnosis Adrenal Gland Neoplasms - secondary Adult Aged Bone Neoplasms - diagnosis Bone Neoplasms - secondary Brain Neoplasms - diagnosis Brain Neoplasms - secondary Breast Neoplasms - diagnosis Colonic Neoplasms - diagnosis Female Humans Image Enhancement - methods Imaging, Three-Dimensional - methods Liver Neoplasms - diagnosis Liver Neoplasms - secondary Lung Neoplasms - diagnosis Lung Neoplasms - secondary Lymphatic Metastasis Magnetic Resonance Imaging - methods Male Mass Screening Middle Aged Neoplasm Metastasis - diagnosis Neoplasm Metastasis - pathology Neoplasm Staging Ovarian Neoplasms - diagnosis Skin Neoplasms - diagnosis Skin Neoplasms - secondary Subtraction Technique Tomography, X-Ray Computed - methods Uterine Neoplasms - diagnosis Whole Body Imaging
ISSN:	1537-453X, 1537-453X
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Shrnutí:	To evaluate 3D Volumetric Interpolated Breath-hold Examination (VIBE) whole-body MRI (WB-MRI) acquisition for the metastases staging. Thirty-two consecutive patients with solid tumor were examined from head to feet before and after contrast injection. An automatic subtraction occurred between the 2 series of images. WB-MRI was compared with conventional staging techniques (CT, scintigraphy, brain MRI, and whole-body PET in 4 cases). WB-MRI and the reference techniques depicted metastases in 25 patients. WB-MRI depicted more bone lesions in the spine, pelvis, skull, femur, and tibia, whereas scintigraphy detected more rib lesions. WB-MRI depicted 27 cerebral metastases, whereas brain MRI depicted 40 cerebral metastases. WB-MRI depicted a total of 8 hepatic metastases, 8 adrenal lesions, and conventional staging 7 hepatic metastases and 10 adrenal lesions. WB-MRI examination depicted lung metastases in 10 patients, and CT examination in 13 patients. The results of this study indicate that WB-MRI is a feasible and promising technique for tumor staging.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1537-453X 1537-453X
DOI:	10.1097/COC.0b013e31815e3ff4