Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

Tumor-infiltrating myeloid cells (TIMs) are crucial cell populations involved in tumor immune escape, and their functions are regulated by multiple epigenetic mechanisms. The precise regulation mode of RNA N6-methyladenosine (m6A) modification in controlling TIM function is still poorly understood....

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Bibliographic Details

Published in:	Molecular cell Vol. 82; no. 9; p. 1660
Main Authors:	Xiong, Jia, He, Jia, Zhu, Jun, Pan, Jiongli, Liao, Weijie, Ye, Hongying, Wang, Haofei, Song, Yinjing, Du, Yue, Cui, Bijun, Xue, Maoguang, Zheng, Wanling, Kong, Xiangxing, Jiang, Kai, Ding, Kefeng, Lai, Lihua, Wang, Qingqing
Format:	Journal Article
Language:	English
Published:	05.05.2022
ISSN:	1097-4164, 1097-4164
Online Access:	Get more information
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