Assessment of Nucleotide Excision Repair XPD Polymorphisms in the Peripheral Blood of Gemcitabine/Cisplatin–Treated Advanced Non–Small-Cell Lung Cancer Patients

Only about one third of non—small-cell lung cancer (NSCLC) patients respond to cisplatin-based chemotherapy. Cisplatin DNA adducts are commonly repaired through the nucleotide excision repair pathway. The study of rare inherited disorders such as xeroderma pigmentosum and Cockayne syndrome has discl...

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Veröffentlicht in:	Clinical lung cancer Jg. 4; H. 4; S. 237 - 241
Hauptverfasser:	Camps, Carlos, Sarries, Carmen, Roig, Bárbara, Javier Sánchez, José, Queralt, Cristina, Sancho, Eva, Martinez, Natividad, Tarón, Miguel, Rosell, Rafael
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 01.01.2003
Schlagworte:	Chemotherapy resistance Cockayne syndrome DNA adducts DNA repair ERCC1 Transcription-coupled repair Xeroderma pigmentosum genes Cockayne syndrome Chemotherapy resistance ERCC1 DNA adducts DNA repair Transcription-coupled repair Xeroderma pigmentosum genes
ISSN:	1525-7304, 1938-0690
Online-Zugang:	Volltext
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