A stepwise approach toward closed-loop blood glucose control for intensive care unit patients: results from a feasibility study in type 1 diabetic subjects using vascular microdialysis with infrared spectrometry and a model predictive control algorithm

Glycemic control can reduce the mortality and morbidity of intensive care patients. The CLINICIP (closed-loop insulin infusion for critically ill patients) project aimed to develop a closed-loop control system for this patient group. Following a stepwise approach, we combined three independently tes...

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Bibliographic Details
Published in:	Journal of diabetes science and technology Vol. 5; no. 4; p. 901
Main Authors:	Feichtner, Franz, Mader, Julia K, Schaller, Roland, Schaupp, Lukas, Ellmerer, Martin, Korsatko, Stefan, Kondepati, Venkata R, Heise, H Michael, Wilinska, Malgorzata E, Hovorka, Roman, Pieber, Thomas R
Format:	Journal Article
Language:	English
Published:	United States 01.07.2011
Subjects:	Adult Algorithms Biosensing Techniques - instrumentation Biosensing Techniques - methods Blood Chemical Analysis - instrumentation Blood Chemical Analysis - methods Blood Glucose - analysis Blood Glucose - metabolism Blood Vessels - chemistry Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - diagnosis Diabetes Mellitus, Type 1 - drug therapy Feasibility Studies Female Humans Hypoglycemic Agents - administration & dosage Insulin - administration & dosage Insulin Infusion Systems Intensive Care Units Male Microdialysis - methods Microdialysis - statistics & numerical data Middle Aged Models, Statistical Monitoring, Physiologic - instrumentation Monitoring, Physiologic - methods Prognosis Spectrophotometry, Infrared Young Adult
ISSN:	1932-2968, 1932-3107
Online Access:	Get more information
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