Catecholaminergic activity among young adults after high phosphorus intake during childhood and adolescence

Elevated catecholamine secretion has been reported after high dietary phosphate intake in experimental studies in animals and humans. This study thus aimed to examine the prospective relationship between long-term dietary phosphorus intake during childhood and adolescence-assessed via 24-h urinary p...

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Published in:	Hormones (Athens, Greece)
Main Authors:	Franco, Luciana Peixoto, Derakhshandeh-Rishehri, Seyedeh-Masomeh, Nöthlings, Ute, Kalhoff, Hermann, Peitzsch, Mirko, Wudy, Stefan A., Remer, Thomas
Format:	Journal Article
Language:	English
Published:	Switzerland 12.11.2025
Subjects:	Epinephrine 24-h urinary biomarkers Catecholamines Phosphorus intake Norepinephrine Children Phosphate excretion
ISSN:	1109-3099, 2520-8721, 2520-8721
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Abstract	Elevated catecholamine secretion has been reported after high dietary phosphate intake in experimental studies in animals and humans. This study thus aimed to examine the prospective relationship between long-term dietary phosphorus intake during childhood and adolescence-assessed via 24-h urinary phosphate excretion-and catecholamine levels in adulthood. A total of 159 healthy participants of the DONALD Study (Dortmund, Germany) were examined, who had repeatedly provided 24-h urine samples between ages 3 and 17 years and from whom a 24-h specimen was collected again in young adulthood (ages 18-35). In the adult samples, urinary free epinephrine (EPI), norepinephrine (NE) and the O-methylated EPI- and NE-metabolites metanephrine and normetanephrine were quantified using LC-MS/MS. Phosphate was measured ion chromatographically. Individual means of standard deviation scores were calculated for urinary phosphate and further biomarker excretions as well as for anthropometric data longitudinally determined between 3 and 17 years. Multivariable linear regression was used to investigate associations between pre-adulthood phosphate and adult catecholamine excretions. After fully adjusting for growth- and adulthood-related covariates, only females' renal excretions of EPI (p=0.030) and NE (p=0.040) were associated significantly with pre-adulthood phosphate excretion. In line with a disease-free, relatively continuous adrenal-medullary production of O-methylated metabolites, no association at all was seen for metanephrine and normetanephrine. Our study provides biomarker-based evidence that habitual high dietary phosphorus intake during childhood and adolescence may be related to elevated catecholaminergic activity in adulthood, at least in females, potentially contributing in the long term to endocrine-metabolic-related neuronal and cardiovascular disorders.
AbstractList	Elevated catecholamine secretion has been reported after high dietary phosphate intake in experimental studies in animals and humans. This study thus aimed to examine the prospective relationship between long-term dietary phosphorus intake during childhood and adolescence-assessed via 24-h urinary phosphate excretion-and catecholamine levels in adulthood.PURPOSEElevated catecholamine secretion has been reported after high dietary phosphate intake in experimental studies in animals and humans. This study thus aimed to examine the prospective relationship between long-term dietary phosphorus intake during childhood and adolescence-assessed via 24-h urinary phosphate excretion-and catecholamine levels in adulthood.A total of 159 healthy participants of the DONALD Study (Dortmund, Germany) were examined, who had repeatedly provided 24-h urine samples between ages 3 and 17 years and from whom a 24-h specimen was collected again in young adulthood (ages 18-35). In the adult samples, urinary free epinephrine (EPI), norepinephrine (NE) and the O-methylated EPI- and NE-metabolites metanephrine and normetanephrine were quantified using LC-MS/MS. Phosphate was measured ion chromatographically. Individual means of standard deviation scores were calculated for urinary phosphate and further biomarker excretions as well as for anthropometric data longitudinally determined between 3 and 17 years. Multivariable linear regression was used to investigate associations between pre-adulthood phosphate and adult catecholamine excretions.METHODSA total of 159 healthy participants of the DONALD Study (Dortmund, Germany) were examined, who had repeatedly provided 24-h urine samples between ages 3 and 17 years and from whom a 24-h specimen was collected again in young adulthood (ages 18-35). In the adult samples, urinary free epinephrine (EPI), norepinephrine (NE) and the O-methylated EPI- and NE-metabolites metanephrine and normetanephrine were quantified using LC-MS/MS. Phosphate was measured ion chromatographically. Individual means of standard deviation scores were calculated for urinary phosphate and further biomarker excretions as well as for anthropometric data longitudinally determined between 3 and 17 years. Multivariable linear regression was used to investigate associations between pre-adulthood phosphate and adult catecholamine excretions.After fully adjusting for growth- and adulthood-related covariates, only females' renal excretions of EPI (p=0.030) and NE (p=0.040) were associated significantly with pre-adulthood phosphate excretion. In line with a disease-free, relatively continuous adrenal-medullary production of O-methylated metabolites, no association at all was seen for metanephrine and normetanephrine.RESULTSAfter fully adjusting for growth- and adulthood-related covariates, only females' renal excretions of EPI (p=0.030) and NE (p=0.040) were associated significantly with pre-adulthood phosphate excretion. In line with a disease-free, relatively continuous adrenal-medullary production of O-methylated metabolites, no association at all was seen for metanephrine and normetanephrine.Our study provides biomarker-based evidence that habitual high dietary phosphorus intake during childhood and adolescence may be related to elevated catecholaminergic activity in adulthood, at least in females, potentially contributing in the long term to endocrine-metabolic-related neuronal and cardiovascular disorders.CONCLUSIONOur study provides biomarker-based evidence that habitual high dietary phosphorus intake during childhood and adolescence may be related to elevated catecholaminergic activity in adulthood, at least in females, potentially contributing in the long term to endocrine-metabolic-related neuronal and cardiovascular disorders. Elevated catecholamine secretion has been reported after high dietary phosphate intake in experimental studies in animals and humans. This study thus aimed to examine the prospective relationship between long-term dietary phosphorus intake during childhood and adolescence-assessed via 24-h urinary phosphate excretion-and catecholamine levels in adulthood. A total of 159 healthy participants of the DONALD Study (Dortmund, Germany) were examined, who had repeatedly provided 24-h urine samples between ages 3 and 17 years and from whom a 24-h specimen was collected again in young adulthood (ages 18-35). In the adult samples, urinary free epinephrine (EPI), norepinephrine (NE) and the O-methylated EPI- and NE-metabolites metanephrine and normetanephrine were quantified using LC-MS/MS. Phosphate was measured ion chromatographically. Individual means of standard deviation scores were calculated for urinary phosphate and further biomarker excretions as well as for anthropometric data longitudinally determined between 3 and 17 years. Multivariable linear regression was used to investigate associations between pre-adulthood phosphate and adult catecholamine excretions. After fully adjusting for growth- and adulthood-related covariates, only females' renal excretions of EPI (p=0.030) and NE (p=0.040) were associated significantly with pre-adulthood phosphate excretion. In line with a disease-free, relatively continuous adrenal-medullary production of O-methylated metabolites, no association at all was seen for metanephrine and normetanephrine. Our study provides biomarker-based evidence that habitual high dietary phosphorus intake during childhood and adolescence may be related to elevated catecholaminergic activity in adulthood, at least in females, potentially contributing in the long term to endocrine-metabolic-related neuronal and cardiovascular disorders.
Author	Derakhshandeh-Rishehri, Seyedeh-Masomeh Wudy, Stefan A. Kalhoff, Hermann Nöthlings, Ute Peitzsch, Mirko Remer, Thomas Franco, Luciana Peixoto
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Cites_doi	10.1007/s00424-023-02793-0 10.3390/nu15163510 10.1159/000118364 10.1038/s41380-021-01133-x 10.1016/j.clinbiochem.2014.09.009 10.3109/08037059609062103 10.1152/physrev.00042.2006 10.1161/01.HYP.0000203952.27988.79 10.1210/jc.2016-2677 10.1136/hrt.2010.199760 10.1093/ajcn/nqac116 10.1152/jappl.1990.69.2.710 10.1007/BF00422893 10.1124/pr.56.3.1 10.1007/s00103-012-1503-6 10.1111/j.1467-9450.1975.tb00197.x 10.1681/ASN.2017121254 10.1152/japplphysiol.90812.2008 10.1152/ajpendo.1987.253.3.E322 10.1016/j.cmet.2024.09.012 10.2337/diacare.27.6.1487 10.1210/jcem.84.2.5447 10.1007/s00394-023-03290-x 10.1093/ajcn/75.3.561 10.1080/140174301317116271 10.1007/BF00246749 10.53941/ijddp.2023.100012 10.1016/j.lfs.2021.120106 10.2165/00003495-197816050-00003 10.1007/BF00431970 10.1002/cphy.c190003 10.1016/j.cca.2012.12.031 10.1093/ajcn/77.5.1255 10.7326/0003-4819-93-4-566 10.1007/s00394-004-0445-7 10.1136/jcp.s3-4.1.73 10.3390/biomedicines10102510 10.1097/00003246-198211000-00010
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References	MH Slaughter (735_CR15) 1988; 60 AE Ross (735_CR23) 2001; 35 Y Du (735_CR38) 2021; 287 M Barton (735_CR28) 1982; 10 J Esche (735_CR19) 2016; 101 T Remer (735_CR18) 2003; 77 AL Myrsten (735_CR30) 1975; 16 M Lehmann (735_CR32) 1986; 55 J Claustre (735_CR33) 1980; 67 PW Gold (735_CR37) 2021; 26 K Sakamoto (735_CR40) 2025; 37 SE Kjeldsen (735_CR7) 1996; 5 A Flaa (735_CR6) 2006; 47 MS Calvo (735_CR41) 2023 JD Brofman (735_CR29) 1990; 69 V Maneu (735_CR4) 2023; 475 T Remer (735_CR16) 2014; 47 GG Nahas (735_CR27) 1970 A Kroke (735_CR12) 2004; 43 735_CR22 PA Komesaroff (735_CR34) 1999; 84 R Kvetnansky (735_CR5) 2009; 89 GT Livezey (735_CR31) 1987; 17 TM Wallace (735_CR21) 2004; 27 I Perrar (735_CR11) 2024; 63 G Eisenhofer (735_CR3) 2004; 56 S Hamburg (735_CR8) 1980; 93 MA Staten (735_CR35) 1987; 253 A Philippu (735_CR26) 1966; 252 E Carbone (735_CR1) 2019; 9 735_CR14 735_CR39 N Latic (735_CR10) 2022 M Peitzsch (735_CR20) 2013; 418 PR Mitoff (735_CR36) 2011; 97 AE Buyken (735_CR13) 2012; 55 J Mohammad (735_CR9) 2018; 29 T Remer (735_CR17) 2002; 75 TJ Horton (735_CR24) 2009; 107 R Laverty (735_CR2) 1978; 16 CN Duong (735_CR25) 2022; 116
References_xml	– volume: 475 start-page: 667 year: 2023 ident: 735_CR4 publication-title: Pflugers Arch doi: 10.1007/s00424-023-02793-0 – year: 2023 ident: 735_CR41 publication-title: Nutrients doi: 10.3390/nu15163510 – volume: 17 start-page: 193 year: 1987 ident: 735_CR31 publication-title: Neuropsychobiology doi: 10.1159/000118364 – volume: 26 start-page: 6121 issue: 11 year: 2021 ident: 735_CR37 publication-title: Mol Psychiatry doi: 10.1038/s41380-021-01133-x – volume: 60 start-page: 709 year: 1988 ident: 735_CR15 publication-title: Hum Biol – volume: 47 start-page: 307 year: 2014 ident: 735_CR16 publication-title: Clin Biochem doi: 10.1016/j.clinbiochem.2014.09.009 – volume: 5 start-page: 27 year: 1996 ident: 735_CR7 publication-title: Blood Press doi: 10.3109/08037059609062103 – volume: 89 start-page: 535 year: 2009 ident: 735_CR5 publication-title: Physiol Rev doi: 10.1152/physrev.00042.2006 – volume: 47 start-page: 396 year: 2006 ident: 735_CR6 publication-title: Hypertension doi: 10.1161/01.HYP.0000203952.27988.79 – volume: 101 start-page: 4914 year: 2016 ident: 735_CR19 publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2016-2677 – volume: 97 start-page: 382 year: 2011 ident: 735_CR36 publication-title: Heart doi: 10.1136/hrt.2010.199760 – volume: 116 start-page: 541 year: 2022 ident: 735_CR25 publication-title: Am J Clin Nutr doi: 10.1093/ajcn/nqac116 – volume: 69 start-page: 710 year: 1990 ident: 735_CR29 publication-title: J Appl Physiol doi: 10.1152/jappl.1990.69.2.710 – volume: 55 start-page: 54 year: 1986 ident: 735_CR32 publication-title: Eur J Appl Physiol Occup Physiol doi: 10.1007/BF00422893 – volume: 56 start-page: 331 year: 2004 ident: 735_CR3 publication-title: Pharmacol Rev doi: 10.1124/pr.56.3.1 – volume: 55 start-page: 875 year: 2012 ident: 735_CR13 publication-title: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz doi: 10.1007/s00103-012-1503-6 – volume: 16 start-page: 303 year: 1975 ident: 735_CR30 publication-title: Scand J Psychol doi: 10.1111/j.1467-9450.1975.tb00197.x – volume: 29 start-page: 2089 year: 2018 ident: 735_CR9 publication-title: J Am Soc Nephrol doi: 10.1681/ASN.2017121254 – volume: 107 start-page: 200 issue: 1 year: 2009 ident: 735_CR24 publication-title: J Appl Physiol doi: 10.1152/japplphysiol.90812.2008 – volume: 253 year: 1987 ident: 735_CR35 publication-title: Am J Physiol doi: 10.1152/ajpendo.1987.253.3.E322 – volume: 37 start-page: 121 issue: 1 year: 2025 ident: 735_CR40 publication-title: Cell Metab doi: 10.1016/j.cmet.2024.09.012 – volume: 27 start-page: 1487 year: 2004 ident: 735_CR21 publication-title: Diabetes Care doi: 10.2337/diacare.27.6.1487 – volume: 84 start-page: 606 year: 1999 ident: 735_CR34 publication-title: J Clin Endocrinol Metab doi: 10.1210/jcem.84.2.5447 – volume: 63 start-page: 727 year: 2024 ident: 735_CR11 publication-title: Eur J Nutr doi: 10.1007/s00394-023-03290-x – volume: 75 start-page: 561 year: 2002 ident: 735_CR17 publication-title: Am J Clin Nutr doi: 10.1093/ajcn/75.3.561 – volume: 35 start-page: 307 year: 2001 ident: 735_CR23 publication-title: Scand Cardiovasc J doi: 10.1080/140174301317116271 – volume: 252 start-page: 339 year: 1966 ident: 735_CR26 publication-title: Naunyn Schmiedebergs Arch Exp Pathol Pharmakol doi: 10.1007/BF00246749 – ident: 735_CR39 doi: 10.53941/ijddp.2023.100012 – volume: 287 year: 2021 ident: 735_CR38 publication-title: Life Sci doi: 10.1016/j.lfs.2021.120106 – volume: 16 start-page: 418 year: 1978 ident: 735_CR2 publication-title: Drugs doi: 10.2165/00003495-197816050-00003 – volume: 67 start-page: 147 year: 1980 ident: 735_CR33 publication-title: Psychopharmacology doi: 10.1007/BF00431970 – volume: 9 start-page: 1443 year: 2019 ident: 735_CR1 publication-title: Compr Physiol doi: 10.1002/cphy.c190003 – ident: 735_CR14 – volume: 418 start-page: 50 year: 2013 ident: 735_CR20 publication-title: Clin Chim Acta doi: 10.1016/j.cca.2012.12.031 – ident: 735_CR22 – volume: 77 start-page: 1255 year: 2003 ident: 735_CR18 publication-title: Am J Clin Nutr doi: 10.1093/ajcn/77.5.1255 – volume: 93 start-page: 566 year: 1980 ident: 735_CR8 publication-title: Ann Intern Med doi: 10.7326/0003-4819-93-4-566 – volume: 43 start-page: 45 year: 2004 ident: 735_CR12 publication-title: Eur J Nutr doi: 10.1007/s00394-004-0445-7 – year: 1970 ident: 735_CR27 publication-title: J Clin Pathol Suppl (R Coll Pathol) doi: 10.1136/jcp.s3-4.1.73 – year: 2022 ident: 735_CR10 publication-title: Biomedicines doi: 10.3390/biomedicines10102510 – volume: 10 start-page: 751 year: 1982 ident: 735_CR28 publication-title: Crit Care Med doi: 10.1097/00003246-198211000-00010
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