Efficacy of the Nav1.7 blocker PF-05089771 in a randomised, placebo-controlled, double-blind clinical study in subjects with painful diabetic peripheral neuropathy

The effect of PF-05089771, a selective, peripherally restricted Nav1.7 sodium channel blocker on pain due to diabetic peripheral neuropathy was investigated in a randomised, placebo and active-controlled parallel group clinical trial (NCT02215252). A 1-week placebo-run in the period was followed by...

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Vydáno v:	Pain (Amsterdam) Ročník 159; číslo 8; s. 1465
Hlavní autoři:	McDonnell, Aoibhinn, Collins, Susie, Ali, Zahid, Iavarone, Laura, Surujbally, Raulin, Kirby, Simon, Butt, Richard P
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.08.2018
Témata:	Adult Aged Diabetic Neuropathies - drug therapy Double-Blind Method Female Humans Male Middle Aged Neuralgia - drug therapy Phenyl Ethers - therapeutic use Pregabalin - therapeutic use Sodium Channel Blockers - therapeutic use Sulfonamides - therapeutic use Treatment Outcome
ISSN:	1872-6623, 1872-6623
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