Impact of physiologically relevant temperatures on dermal absorption of active substances - an ex-vivo study in human skin

Skin temperature plays a certain role in the dermal absorption of substances, but the extent and mechanisms of skin temperatures-induced modulation in ranges caused by physiological thermoregulation or environmental conditions are largely unknown. The influence of dermal temperature on the absorptio...

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Vydáno v:	Toxicology in vitro Ročník 68; s. 104954
Hlavní autoři:	Kilo, S., Wick, J., Mini Vijayan, S., Göen, T., Horch, R.E., Ludolph, I., Drexler, H.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Elsevier Ltd 01.10.2020 Elsevier Science Ltd
Témata:	Absorption Anisole Anisoles - metabolism Blood circulation Dermal absorption Diffusion cell Diffusion cells Dioxanes - metabolism Environmental conditions Ethanol Ethanol - metabolism Exposure Humans Influence of temperature Lipids Lipophilic Modulation Penetration Perfusion Skin Skin - metabolism Skin Absorption Skin temperature Temperature Temperature dependence Thermoregulation Transdermal penetration LOD SC CAS Log P SEM Transdermal penetration Influence of temperature Dermal absorption Diffusion cell
ISSN:	0887-2333, 1879-3177, 1879-3177
On-line přístup:	Získat plný text
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