SHBG Gene Polymorphisms and Their Influence on Serum SHBG, Total and Free Testosterone Concentrations in Men

Genetic variation in SHBG structure may affect estimates of sex steroid exposure by altering the affinity of the protein for its ligand. Consequently, free hormone calculations assuming constant binding affinity may, for certain genetic variations, lead to incorrect diagnoses if genetic variation is...

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Bibliographic Details
Published in:	The journal of clinical endocrinology and metabolism Vol. 110; no. 3; p. e641
Main Authors:	Walravens, Joeri, Sleumer, Bas, Vos, Michel J, Snaterse, Gido, Narinx, Nick, Antonio, Leen, Reyns, Tim, Fiers, Tom, Kema, Ido P, Kaufman, Jean-Marc, van de Merbel, Nico C, Lapauw, Bruno
Format:	Journal Article
Language:	English
Published:	United States 18.02.2025
Subjects:	Adult Gene Frequency Genotype Humans Male Middle Aged Polymorphism, Single Nucleotide Sex Hormone-Binding Globulin - analysis Sex Hormone-Binding Globulin - genetics Sex Hormone-Binding Globulin - metabolism Testosterone - blood healthy men LC-MS/MS free testosterone testosterone SHBG polymorphisms
ISSN:	1945-7197, 1945-7197
Online Access:	Get more information
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