Fusing Higher and Lower-Order Biological Information for Drug Repositioning via Graph Representation Learning

Drug repositioning is a promising drug development technique to identify new indications for existing drugs. However, existing computational models only make use of lower-order biological information at the level of individual drugs, diseases and their associations, but few of them can take into acc...

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Veröffentlicht in:IEEE transactions on emerging topics in computing Jg. 12; H. 1; S. 163 - 176
Hauptverfasser: Zhao, Bo-Wei, Wang, Lei, Hu, Peng-Wei, Wong, Leon, Su, Xiao-Rui, Wang, Bao-Quan, You, Zhu-Hong, Hu, Lun
Format: Journal Article
Sprache:Englisch
Veröffentlicht: New York IEEE 01.01.2024
The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
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ISSN:2168-6750, 2168-6750
Online-Zugang:Volltext
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