Imaging of Renal Transplant Complications throughout the Life of the Allograft: Comprehensive Multimodality Review
The kidney is the most commonly transplanted solid organ. Advances in surgical techniques, immunosuppression regimens, surveillance imaging, and histopathologic diagnosis of rejection have allowed prolonged graft survival times. However, the demand for kidneys continues to outgrow the available supp...
Uložené v:
| Vydané v: | Radiographics Ročník 39; číslo 5; s. 1327 |
|---|---|
| Hlavní autori: | , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
United States
01.09.2019
|
| Predmet: | |
| ISSN: | 1527-1323, 1527-1323 |
| On-line prístup: | Zistit podrobnosti o prístupe |
| Tagy: |
Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
|
| Abstract | The kidney is the most commonly transplanted solid organ. Advances in surgical techniques, immunosuppression regimens, surveillance imaging, and histopathologic diagnosis of rejection have allowed prolonged graft survival times. However, the demand for kidneys continues to outgrow the available supply, and there are efforts to increase use of donor kidneys with moderate- or high-risk profiles. This highlights the importance of evaluating the renal transplant patient in the context of both donor and recipient risk factors. Radiologists play an integral role within the multidisciplinary team in care of the transplant patient at every stage of the transplant process. In the immediate postoperative period, duplex US is the modality of choice for evaluating the renal allograft. It is useful for establishing a baseline examination for comparison at future surveillance imaging. In the setting of allograft dysfunction, advanced imaging techniques including MRI or contrast-enhanced US may be useful for providing a more specific diagnosis and excluding nonrejection causes of renal dysfunction. When a pathologic diagnosis is deemed necessary to guide therapy, US-guided biopsy is a relatively low-risk, safe procedure. The range of complications of renal transplantation can be organized temporally in relation to the time since surgery and/or according to disease categories, including immunologic (rejection), surgical or iatrogenic, vascular, urinary, infectious, and neoplastic complications. The unique heterotopic location of the renal allograft in the iliac fossa predisposes it to a specific set of complications. As imaging features of infection or malignancy may be nonspecific, awareness of the patient's risk profile and time since transplantation can be used to assign the probability of a certain diagnosis and thus guide more specific diagnostic workup. It is critical to understand variations in vascular anatomy, surgical technique, and independent donor and recipient risk factors to make an accurate diagnosis and initiate appropriate treatment.
RSNA, 2019. |
|---|---|
| AbstractList | The kidney is the most commonly transplanted solid organ. Advances in surgical techniques, immunosuppression regimens, surveillance imaging, and histopathologic diagnosis of rejection have allowed prolonged graft survival times. However, the demand for kidneys continues to outgrow the available supply, and there are efforts to increase use of donor kidneys with moderate- or high-risk profiles. This highlights the importance of evaluating the renal transplant patient in the context of both donor and recipient risk factors. Radiologists play an integral role within the multidisciplinary team in care of the transplant patient at every stage of the transplant process. In the immediate postoperative period, duplex US is the modality of choice for evaluating the renal allograft. It is useful for establishing a baseline examination for comparison at future surveillance imaging. In the setting of allograft dysfunction, advanced imaging techniques including MRI or contrast-enhanced US may be useful for providing a more specific diagnosis and excluding nonrejection causes of renal dysfunction. When a pathologic diagnosis is deemed necessary to guide therapy, US-guided biopsy is a relatively low-risk, safe procedure. The range of complications of renal transplantation can be organized temporally in relation to the time since surgery and/or according to disease categories, including immunologic (rejection), surgical or iatrogenic, vascular, urinary, infectious, and neoplastic complications. The unique heterotopic location of the renal allograft in the iliac fossa predisposes it to a specific set of complications. As imaging features of infection or malignancy may be nonspecific, awareness of the patient's risk profile and time since transplantation can be used to assign the probability of a certain diagnosis and thus guide more specific diagnostic workup. It is critical to understand variations in vascular anatomy, surgical technique, and independent donor and recipient risk factors to make an accurate diagnosis and initiate appropriate treatment.
RSNA, 2019. The kidney is the most commonly transplanted solid organ. Advances in surgical techniques, immunosuppression regimens, surveillance imaging, and histopathologic diagnosis of rejection have allowed prolonged graft survival times. However, the demand for kidneys continues to outgrow the available supply, and there are efforts to increase use of donor kidneys with moderate- or high-risk profiles. This highlights the importance of evaluating the renal transplant patient in the context of both donor and recipient risk factors. Radiologists play an integral role within the multidisciplinary team in care of the transplant patient at every stage of the transplant process. In the immediate postoperative period, duplex US is the modality of choice for evaluating the renal allograft. It is useful for establishing a baseline examination for comparison at future surveillance imaging. In the setting of allograft dysfunction, advanced imaging techniques including MRI or contrast-enhanced US may be useful for providing a more specific diagnosis and excluding nonrejection causes of renal dysfunction. When a pathologic diagnosis is deemed necessary to guide therapy, US-guided biopsy is a relatively low-risk, safe procedure. The range of complications of renal transplantation can be organized temporally in relation to the time since surgery and/or according to disease categories, including immunologic (rejection), surgical or iatrogenic, vascular, urinary, infectious, and neoplastic complications. The unique heterotopic location of the renal allograft in the iliac fossa predisposes it to a specific set of complications. As imaging features of infection or malignancy may be nonspecific, awareness of the patient's risk profile and time since transplantation can be used to assign the probability of a certain diagnosis and thus guide more specific diagnostic workup. It is critical to understand variations in vascular anatomy, surgical technique, and independent donor and recipient risk factors to make an accurate diagnosis and initiate appropriate treatment.©RSNA, 2019.The kidney is the most commonly transplanted solid organ. Advances in surgical techniques, immunosuppression regimens, surveillance imaging, and histopathologic diagnosis of rejection have allowed prolonged graft survival times. However, the demand for kidneys continues to outgrow the available supply, and there are efforts to increase use of donor kidneys with moderate- or high-risk profiles. This highlights the importance of evaluating the renal transplant patient in the context of both donor and recipient risk factors. Radiologists play an integral role within the multidisciplinary team in care of the transplant patient at every stage of the transplant process. In the immediate postoperative period, duplex US is the modality of choice for evaluating the renal allograft. It is useful for establishing a baseline examination for comparison at future surveillance imaging. In the setting of allograft dysfunction, advanced imaging techniques including MRI or contrast-enhanced US may be useful for providing a more specific diagnosis and excluding nonrejection causes of renal dysfunction. When a pathologic diagnosis is deemed necessary to guide therapy, US-guided biopsy is a relatively low-risk, safe procedure. The range of complications of renal transplantation can be organized temporally in relation to the time since surgery and/or according to disease categories, including immunologic (rejection), surgical or iatrogenic, vascular, urinary, infectious, and neoplastic complications. The unique heterotopic location of the renal allograft in the iliac fossa predisposes it to a specific set of complications. As imaging features of infection or malignancy may be nonspecific, awareness of the patient's risk profile and time since transplantation can be used to assign the probability of a certain diagnosis and thus guide more specific diagnostic workup. It is critical to understand variations in vascular anatomy, surgical technique, and independent donor and recipient risk factors to make an accurate diagnosis and initiate appropriate treatment.©RSNA, 2019. |
| Author | Sugi, Mark D Maddu, Kiran K Dahiya, Nirvikar Menias, Christine O Joshi, Gayatri |
| Author_xml | – sequence: 1 givenname: Mark D orcidid: 0000-0002-2154-3990 surname: Sugi fullname: Sugi, Mark D organization: From the Department of Radiology, Mayo Clinic, Scottsdale, Ariz (M.D.S., N.D., C.O.M.); and Departments of Radiology and Imaging Sciences (G.J., K.K.M.) and Emergency Medicine (G.J., K.K.M.), Emory University School of Medicine, Atlanta, Ga – sequence: 2 givenname: Gayatri orcidid: 0000-0002-1138-9280 surname: Joshi fullname: Joshi, Gayatri organization: From the Department of Radiology, Mayo Clinic, Scottsdale, Ariz (M.D.S., N.D., C.O.M.); and Departments of Radiology and Imaging Sciences (G.J., K.K.M.) and Emergency Medicine (G.J., K.K.M.), Emory University School of Medicine, Atlanta, Ga – sequence: 3 givenname: Kiran K surname: Maddu fullname: Maddu, Kiran K organization: From the Department of Radiology, Mayo Clinic, Scottsdale, Ariz (M.D.S., N.D., C.O.M.); and Departments of Radiology and Imaging Sciences (G.J., K.K.M.) and Emergency Medicine (G.J., K.K.M.), Emory University School of Medicine, Atlanta, Ga – sequence: 4 givenname: Nirvikar surname: Dahiya fullname: Dahiya, Nirvikar organization: From the Department of Radiology, Mayo Clinic, Scottsdale, Ariz (M.D.S., N.D., C.O.M.); and Departments of Radiology and Imaging Sciences (G.J., K.K.M.) and Emergency Medicine (G.J., K.K.M.), Emory University School of Medicine, Atlanta, Ga – sequence: 5 givenname: Christine O surname: Menias fullname: Menias, Christine O organization: From the Department of Radiology, Mayo Clinic, Scottsdale, Ariz (M.D.S., N.D., C.O.M.); and Departments of Radiology and Imaging Sciences (G.J., K.K.M.) and Emergency Medicine (G.J., K.K.M.), Emory University School of Medicine, Atlanta, Ga |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31498742$$D View this record in MEDLINE/PubMed |
| BookMark | eNpNkEtPwzAQhC1URB9w5Ipy5JLiVxyHW1XxqFSEhMo5shMnNXLsYjtF_fekUCRO-x1mdnZ2CkbWWQXANYJzhCi_8-0cQ1SgAsKCnYEJynCeIoLJ6B-PwTSEDwgRzTi7AGOCaMFziifArzrRatsmrknelBUm2Xhhw84IG5Ol63ZGVyJqZ0MSt9717db1cUCVrHWjjq4jL4xxrRdNvP_xeLVVNui9Sl56E3XnamF0PAwBe62-LsF5I0xQV6c5A--PD5vlc7p-fVotF-u0wgWJqSpQzXPJ-XBqRjImkSwwI4wJwSjN65w0mGGSi6yhmOBaSFJRATkcEEkp8Qzc_u7deffZqxDLTodKmaGacn0oMeYcwiznZJDenKS97FRd7rzuhD-Uf3_C34KRbJM |
| CitedBy_id | crossref_primary_10_1016_j_acra_2023_02_034 crossref_primary_10_25259_IJN_245_2024 crossref_primary_10_1148_radiol_211855 crossref_primary_10_1007_s00261_024_04477_4 crossref_primary_10_1055_a_1167_8317 crossref_primary_10_1016_j_rcl_2023_04_004 crossref_primary_10_1097_RCT_0000000000001212 crossref_primary_10_1016_j_bjane_2024_844556 crossref_primary_10_3389_fcimb_2024_1473068 crossref_primary_10_1016_j_acra_2020_05_009 crossref_primary_10_1016_j_acra_2024_01_027 crossref_primary_10_1055_s_0042_1760287 crossref_primary_10_4329_wjr_v12_i8_156 crossref_primary_10_1001_jamanetworkopen_2021_27378 crossref_primary_10_1016_j_radcr_2021_04_026 crossref_primary_10_4103_ijnm_ijnm_20_24 crossref_primary_10_1111_petr_70070 crossref_primary_10_3233_CH_211357 crossref_primary_10_1016_j_rcl_2020_03_002 crossref_primary_10_1093_jscr_rjab217 crossref_primary_10_1111_ctr_70048 crossref_primary_10_3389_ti_2023_10556 crossref_primary_10_4103_mjdrdypu_mjdrdypu_299_24 crossref_primary_10_1007_s00330_020_07426_z crossref_primary_10_1007_s00261_024_04731_9 crossref_primary_10_1155_2023_9921063 crossref_primary_10_4103_ijot_ijot_96_22 crossref_primary_10_1016_j_mam_2025_101382 crossref_primary_10_1016_j_rx_2022_04_003 crossref_primary_10_1053_j_akdh_2024_06_002 crossref_primary_10_1038_s41598_020_65267_8 crossref_primary_10_1007_s00261_023_03872_7 crossref_primary_10_1007_s00261_023_03877_2 crossref_primary_10_3390_transplantology6020013 crossref_primary_10_1097_01_CDR_0000897424_11305_7a crossref_primary_10_1111_petr_14607 crossref_primary_10_1259_bjr_20201253 crossref_primary_10_3390_transplantology5020009 crossref_primary_10_1007_s00261_024_04368_8 crossref_primary_10_1016_j_mri_2025_110423 crossref_primary_10_3390_diagnostics11030390 crossref_primary_10_1007_s00261_023_03948_4 crossref_primary_10_1148_rg_230065 crossref_primary_10_1002_jum_15339 crossref_primary_10_2174_1874467217666230803114856 crossref_primary_10_1016_j_crad_2022_12_004 crossref_primary_10_1148_rg_230182 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1148/rg.2019190096 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1527-1323 |
| ExternalDocumentID | 31498742 |
| Genre | Journal Article Review |
| GroupedDBID | --- .GJ 123 169 18M 2WC 34G 39C 4.4 53G 5RE 6PF 7FM AAWTL ABDQB ABOCM ACGFO ACWVV ADBBV AENEX AFOSN AJWWR ALMA_UNASSIGNED_HOLDINGS BAWUL CGR CS3 CUY CVF DU5 E3Z EBS ECM EIF EJD F5P F9R H13 MV1 NPM P2P SJN TR2 TRS TWZ USG W8F WOQ ZGI ZVN ZXP 7X8 |
| ID | FETCH-LOGICAL-c293t-e91d87b884985356b1b926366aa6447d73f26237a5f4232dab3c4a0802da1bbb2 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 50 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000484828500010&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1527-1323 |
| IngestDate | Thu Oct 02 12:06:39 EDT 2025 Thu Apr 03 06:59:07 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c293t-e91d87b884985356b1b926366aa6447d73f26237a5f4232dab3c4a0802da1bbb2 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
| ORCID | 0000-0002-2154-3990 0000-0002-1138-9280 |
| PMID | 31498742 |
| PQID | 2288005783 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_2288005783 pubmed_primary_31498742 |
| PublicationCentury | 2000 |
| PublicationDate | 2019 Sep-Oct 20190901 |
| PublicationDateYYYYMMDD | 2019-09-01 |
| PublicationDate_xml | – month: 09 year: 2019 text: 2019 Sep-Oct |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Radiographics |
| PublicationTitleAlternate | Radiographics |
| PublicationYear | 2019 |
| SSID | ssj0014586 |
| Score | 2.4927914 |
| SecondaryResourceType | review_article |
| Snippet | The kidney is the most commonly transplanted solid organ. Advances in surgical techniques, immunosuppression regimens, surveillance imaging, and... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 1327 |
| SubjectTerms | Donor Selection Humans Kidney Transplantation Multimodal Imaging Postoperative Complications - diagnostic imaging |
| Title | Imaging of Renal Transplant Complications throughout the Life of the Allograft: Comprehensive Multimodality Review |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/31498742 https://www.proquest.com/docview/2288005783 |
| Volume | 39 |
| WOSCitedRecordID | wos000484828500010&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1bS8MwFA7qRHzxfpk3IvhaZpsuF19kDIeCG0MU9laSJtHB1s6u8_d7knbMF0HwpeShKSU5yflOvpPzIXSjIm5TTUwQM4hNYiHDQNGQB9SRTLFQUgrrxSbYYMBHIzGsD9zmdVrlck_0G7XOU3dG3ooisDQAF5zczz4Dpxrl2NVaQmMdNQhAGWfVbLRiEeK2V3p0yq0BRF1kWWMz5q3i3aV1CXCHt4L-ji69l-nt_vf_9tBOjS9xpzKIfbRmsgO01a8Z9ENUPE29LhHOLX4x7tWqvPkERhh3f-aX41rCJ1-U0DT4eWyN6-XanYkvdW3LO9-nMB9VHjz293mnufboHlfEwxF66z28dh-DWnchSMH5l4ERoeZMcZgrcOZtqkIlIkoolRLQE9OM2AhQE5Nt62heLRVJY-ku7WoZKqWiY7SR5Zk5RdjQVHIAeSLiOmYpxNtaRZRJQm4lfEM10fVyNBOwa0dWyMzki3myGs8mOqmmJJlVBTgSAmEdh5j-7A-9z9G2m-gqLewCNSysanOJNtOvcjwvrrzBwHMw7H8DJGzLPg |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Imaging+of+Renal+Transplant+Complications+throughout+the+Life+of+the+Allograft%3A+Comprehensive+Multimodality+Review&rft.jtitle=Radiographics&rft.au=Sugi%2C+Mark+D&rft.au=Joshi%2C+Gayatri&rft.au=Maddu%2C+Kiran+K&rft.au=Dahiya%2C+Nirvikar&rft.date=2019-09-01&rft.issn=1527-1323&rft.eissn=1527-1323&rft.volume=39&rft.issue=5&rft.spage=1327&rft_id=info:doi/10.1148%2Frg.2019190096&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1527-1323&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1527-1323&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1527-1323&client=summon |