Protein targeting by the itaconate family in immunity and inflammation

Immune cells are metabolically plastic and respond to inflammatory stimuli with large shifts in metabolism. Itaconate is one of the most up-regulated metabolites in macrophages in response to the gram negative bacterial product LPS. As such, itaconate has recently been the subject of intense researc...

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Vydané v:	Biochemical journal Ročník 479; číslo 24; s. 2499
Hlavní autori:	Day, Emily A, O'Neill, Luke A J
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 22.12.2022
Predmet:	Animals Inflammation - drug therapy Inflammation - metabolism Kelch-Like ECH-Associated Protein 1 - metabolism Mice NF-E2-Related Factor 2 - metabolism Succinates - metabolism Succinates - pharmacology infection itaconate post-translational modification immunometabolism inflammation
ISSN:	1470-8728, 1470-8728
On-line prístup:	Zistit podrobnosti o prístupe
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