A Randomized Clinical Trial Evaluating rh-FGF-2/β-TCP in Periodontal Defects

Biological mediators have been used to enhance periodontal regeneration. The aim of this prospective randomized controlled study was to evaluate the safety and effectiveness of 3 doses of fibroblast growth factor 2 (FGF-2) when combined with a β-tricalcium phosphate (β-TCP) scaffold carrier placed i...

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Bibliographic Details
Published in:	Journal of dental research Vol. 95; no. 5; p. 523
Main Authors:	Cochran, D L, Oh, T-J, Mills, M P, Clem, D S, McClain, P K, Schallhorn, R A, McGuire, M K, Scheyer, E T, Giannobile, W V, Reddy, M S, Abou-Arraj, R V, Vassilopoulos, P J, Genco, R J, Geurs, N C, Takemura, A
Format:	Journal Article
Language:	English
Published:	United States 01.05.2016
Subjects:	Adult Aged Alveolar Bone Loss - drug therapy Alveolar Bone Loss - surgery Bone Substitutes - therapeutic use Calcium Phosphates - therapeutic use Dental Scaling - methods Dose-Response Relationship, Drug Double-Blind Method Female Fibroblast Growth Factor 2 - administration & dosage Fibroblast Growth Factor 2 - therapeutic use Follow-Up Studies Guided Tissue Regeneration, Periodontal - methods Humans Male Middle Aged Osteogenesis - drug effects Osteogenesis - physiology Periodontal Attachment Loss - drug therapy Periodontal Attachment Loss - surgery Prospective Studies Recombinant Proteins Root Planing - methods Safety Surgical Flaps - surgery Tissue Scaffolds Treatment Outcome bone substitutes alveolar bone loss regeneration biological factors periodontal disease randomized controlled trial
ISSN:	1544-0591, 1544-0591
Online Access:	Get more information
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