NmRF: identification of multispecies RNA 2’-O-methylation modification sites from RNA sequences

Abstract 2'-O-methylation (Nm) is a post-transcriptional modification of RNA that is catalyzed by 2'-O-methyltransferase and involves replacing the H on the 2′-hydroxyl group with a methyl group. The 2'-O-methylation modification site is detected in a variety of RNA types (miRNA, tRNA...

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Bibliographic Details
Published in:	Briefings in bioinformatics Vol. 23; no. 1
Main Authors:	Ao, Chunyan, Zou, Quan, Yu, Liang
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 17.01.2022 Oxford Publishing Limited (England)
Subjects:	Algorithms Base Sequence Biological activity Computational Biology - methods Gene sequencing Humans Hydroxyl groups Learning algorithms Machine Learning Methylation Methyltransferase miRNA Post-transcription Prediction models Ribonucleic acid RNA RNA - genetics RNA modification tRNA light gradient boosting random forest RNA feature extraction 2’-O-methylation sites
ISSN:	1467-5463, 1477-4054, 1477-4054
Online Access:	Get full text
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