NmRF: identification of multispecies RNA 2’-O-methylation modification sites from RNA sequences

Abstract 2'-O-methylation (Nm) is a post-transcriptional modification of RNA that is catalyzed by 2'-O-methyltransferase and involves replacing the H on the 2′-hydroxyl group with a methyl group. The 2'-O-methylation modification site is detected in a variety of RNA types (miRNA, tRNA...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Briefings in bioinformatics Jg. 23; H. 1
Hauptverfasser:	Ao, Chunyan, Zou, Quan, Yu, Liang
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Oxford University Press 17.01.2022 Oxford Publishing Limited (England)
Schlagworte:	Algorithms Base Sequence Biological activity Computational Biology - methods Gene sequencing Humans Hydroxyl groups Learning algorithms Machine Learning Methylation Methyltransferase miRNA Post-transcription Prediction models Ribonucleic acid RNA RNA - genetics RNA modification tRNA light gradient boosting random forest RNA feature extraction 2’-O-methylation sites
ISSN:	1467-5463, 1477-4054, 1477-4054
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!