Acid‐inhibitory effects of vonoprazan 20 mg compared with esomeprazole 20 mg or rabeprazole 10 mg in healthy adult male subjects ‐ a randomised open‐label cross‐over study

Summary Background Proton pump inhibitors (PPIs) are widely used for the treatment of acid‐related diseases. Vonoprazan is a member of a new class of acid suppressants; potassium‐competitive acid blockers. Vonoprazan may thus be an alternative to PPIs. Aim To evaluate efficacy, rapidity and duration...

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Bibliographic Details
Published in:	Alimentary pharmacology & therapeutics Vol. 42; no. 6; pp. 719 - 730
Main Authors:	Sakurai, Y., Mori, Y., Okamoto, H., Nishimura, A., Komura, E., Araki, T., Shiramoto, M.
Format:	Journal Article
Language:	English
Published:	England 01.09.2015
Subjects:	Adult Cross-Over Studies Esomeprazole - administration & dosage Esomeprazole - adverse effects Esomeprazole - therapeutic use Gastric Acid Humans Hydrogen-Ion Concentration Male Middle Aged Proton Pump Inhibitors - therapeutic use Pyrroles - administration & dosage Pyrroles - adverse effects Pyrroles - therapeutic use Rabeprazole - administration & dosage Rabeprazole - adverse effects Rabeprazole - therapeutic use Research Design Sulfonamides - administration & dosage Sulfonamides - adverse effects Sulfonamides - therapeutic use
ISSN:	0269-2813, 1365-2036, 1365-2036
Online Access:	Get full text
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