Endobronchial Malignant Melanoma: An Exceedingly Rare Occurrence

Malignant melanoma is rarely observed to metastasize to endobronchial tissue. We present a case of endobronchial malignant melanoma in a 36-year-old male smoker with a regressed cutaneous lesion. Due to the limited number of cases and poor survival rate, no definitive treatment options are available...

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Vydáno v:Curēus (Palo Alto, CA) Ročník 12; číslo 6; s. e8619
Hlavní autoři: Ghani, Marium, Skavroneck, Sara R, Adlakha, Kiran, Papali, Alfred
Médium: Journal Article
Jazyk:angličtina
Vydáno: Palo Alto Springer Nature B.V 14.06.2020
Cureus
Témata:
Antigens
Biopsy
Bronchoscopy
Case reports
Immunotherapy
Internal Medicine
Medical prognosis
Melanoma
Metastasis
Oncology
Patients
Pulmonology
Rare diseases
Skin cancer
United States > US
ISSN:2168-8184, 2168-8184
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Abstract Malignant melanoma is rarely observed to metastasize to endobronchial tissue. We present a case of endobronchial malignant melanoma in a 36-year-old male smoker with a regressed cutaneous lesion. Due to the limited number of cases and poor survival rate, no definitive treatment options are available to improve survival in patients with this rare disease presentation. Immunotherapy and surgical removal of locally aggressive tumor have been described, but the definitive role for these therapeutic modalities in the setting of endobronchial metastases remains largely unknown.
AbstractList Malignant melanoma is rarely observed to metastasize to endobronchial tissue. We present a case of endobronchial malignant melanoma in a 36-year-old male smoker with a regressed cutaneous lesion. Due to the limited number of cases and poor survival rate, no definitive treatment options are available to improve survival in patients with this rare disease presentation. Immunotherapy and surgical removal of locally aggressive tumor have been described, but the definitive role for these therapeutic modalities in the setting of endobronchial metastases remains largely unknown.Malignant melanoma is rarely observed to metastasize to endobronchial tissue. We present a case of endobronchial malignant melanoma in a 36-year-old male smoker with a regressed cutaneous lesion. Due to the limited number of cases and poor survival rate, no definitive treatment options are available to improve survival in patients with this rare disease presentation. Immunotherapy and surgical removal of locally aggressive tumor have been described, but the definitive role for these therapeutic modalities in the setting of endobronchial metastases remains largely unknown.
Malignant melanoma is rarely observed to metastasize to endobronchial tissue. We present a case of endobronchial malignant melanoma in a 36-year-old male smoker with a regressed cutaneous lesion. Due to the limited number of cases and poor survival rate, no definitive treatment options are available to improve survival in patients with this rare disease presentation. Immunotherapy and surgical removal of locally aggressive tumor have been described, but the definitive role for these therapeutic modalities in the setting of endobronchial metastases remains largely unknown.
Author Papali, Alfred
Adlakha, Kiran
Ghani, Marium
Skavroneck, Sara R
AuthorAffiliation 2 Internal Medicine, Carolinas Medical Center - Atrium Health, Charlotte, USA
3 Pathology, Carolinas Medical Center - Atrium Health, Charlotte, USA
1 Internal Medicine, Wyckoff Heights Medical Center, New York, USA
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Cites_doi 10.1111/crj.12456
10.1056/NEJMoa1504030
10.1136/bcr-2018-228957
10.1080/02841860310018053
10.1056/NEJMoa1103782
10.1038/sj.bjc.6606030
10.1016/j.lungcan.2014.03.005
10.1158/1078-0432.CCR-16-0906
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Copyright © 2020, Ghani et al.
Copyright © 2020, Ghani et al. 2020 Ghani et al.
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SubjectTerms Antigens
Biopsy
Bronchoscopy
Case reports
Immunotherapy
Internal Medicine
Medical prognosis
Melanoma
Metastasis
Oncology
Patients
Pulmonology
Rare diseases
Skin cancer
Title Endobronchial Malignant Melanoma: An Exceedingly Rare Occurrence
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