The Noncoding Mutational Landscape of Pancreatic Cancer Reveals Recurrent Somatic Mutations in Enhancer Regions

While the coding genome of pancreatic cancer has been characterized in detail, features of the noncoding genome remain relatively unexplored. We used whole-genome sequencing to study the coding and noncoding genomes (promoters, enhancers, and noncoding-nonenhancer regions) in two unique patient coho...

Full description

Bibliographic Details

Published in:	Cancer research communications Vol. 5; no. 10; pp. 1839 - 1851
Main Authors:	Hayashi, Akimasa, Ho, Yu-Jui, Makohon-Moore, Alvin P., Zucker, Amanda, Hong, Jungeui, Umeda, Shigeaki, Karnoub, Elias-Ramzey, Huang, Jinlong, Baez, Priscilla, Kappagantula, Rajya, Melchor, Jerry P., Park, Wungki, O’Reilly, Eileen M., Socci, Nicholas D., Oki, Shinya, Iacobuzio-Donahue, Christine A.
Format:	Journal Article
Language:	English
Published:	United States 01.10.2025
Subjects:	Animals Enhancer Elements, Genetic Gene Expression Regulation, Neoplastic Humans Mice Mutation Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Promoter Regions, Genetic Whole Genome Sequencing
ISSN:	2767-9764, 2767-9764
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!