Characteristic comparison of human induced pluripotent stem cell-derived adult and fetal β-like cells: a differential gene expression analysis

Differentiating human induced pluripotent stem cells (hiPSCs) into β cells for type 1 diabetes (T1D) management is a crucial step. Functionality characterization of hiPSC-derived β cells in some cases, however, only considers morphology and proliferation aspect without examining their distinct molec...

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Bibliographic Details
Published in:	IOP conference series. Earth and environmental science Vol. 1271; no. 1; pp. 12080 - 12090
Main Authors:	Dany, F, Nikmah, U A, Mariya, S S, Panjaitan, N S D, Rinendyaputri, R, Sunarno
Format:	Journal Article
Language:	English
Published:	Bristol IOP Publishing 01.12.2023
Subjects:	adult β-like cells Beta cells Carbohydrate metabolism Carbohydrates Cell differentiation Cell proliferation Clustering Cytology Diabetes mellitus (insulin dependent) differentially expressed genes (DEG) Enrichment fetal β-like cells Fetuses Gene expression GEO human induced pluripotent stem cells (hiPSCs) Molecular properties Pluripotency Ribonucleic acid RNA Stem cells
ISSN:	1755-1307, 1755-1315
Online Access:	Get full text
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