Angiotensin-converting enzyme insertion/deletion gene polymorphism and interferon-β treatment response in multiple sclerosis patients: a preliminary report

We investigated the effect of the functional insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene on the response to interferon-β (IFN-β) therapy in Croatian and Slovenian patients with multiple sclerosis (MS). A total of 275 IFN-β treated MS patients [162 responders...

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Veröffentlicht in:	Pharmacogenetics and genomics Jg. 27; H. 6; S. 232
Hauptverfasser:	Ristić, Smiljana, Starčević Čizmarević, Nada, Lavtar, Polona, Lovrečić, Luca, Perković, Olivio, Sepčić, Juraj, Šega Jazbec, Saša, Kapović, Miljenko, Peterlin, Borut
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.06.2017
Schlagworte:	Adult Antineoplastic Agents - therapeutic use Croatia Female Gene Frequency Genotype Humans INDEL Mutation Interferon-beta - therapeutic use Male Multiple Sclerosis - drug therapy Multiple Sclerosis - genetics Peptidyl-Dipeptidase A - genetics Pharmacogenomic Variants Slovenia Treatment Outcome Young Adult
ISSN:	1744-6880, 1744-6880
Online-Zugang:	Weitere Angaben
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