La3+ and Dy3+ hexaaza macrocycles revisited: Enhanced stabilization of G-quadruplex DNA - spectroscopic and in silico studies

This study explores the synthesis and characterization of two 18-membered hexaaza macrocyclic complexes formed from pyridine-2,6-dicarbaldehyde and trans-1,2-diaminocyclohexane, coordinated with La3+ and Dy3+ ions. We investigate their stabilizing effects on G-quadruplex (G4) structures associated w...

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Bibliographic Details

Published in:	International journal of biological macromolecules Vol. 330; p. 148269
Main Authors:	Ewert, Ernest, Marcinkowski, Dawid, Pospieszna-Markiewicz, Izabela, Palumbo, Rosanna, Hnatejko, Zbigniew, Kubicki, Maciej, Gorczyński, Adam, Wieczorek-Szweda, Ewelina, Patroniak, Violetta, Roviello, Giovanni N., Fik-Jaskółka, Marta
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01.11.2025
Subjects:	c-Myc Dysprosium(III) G-quadruplex Hexaaza macrocycles Lanthanum(III) Pu22 Telomere Hexaaza macrocycles Lanthanum(III) Dysprosium(III) Pu22 c-Myc G-quadruplex Telomere
ISSN:	0141-8130, 1879-0003, 1879-0003
Online Access:	Get full text
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