Systematic pegRNA design with PRIDICT2.0 and ePRIDICT for efficient prime editing

Prime editing is a versatile genome editing technology that enables precise genetic modifications without inducing DNA double-strand breaks. Owing to numerous variables in the prime editing guide RNA (pegRNA) design, experimentally identifying the most efficient pegRNA for a specific locus and edit...

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Bibliographic Details

Published in:	Nature protocols
Main Authors:	Mathis, Nicolas, Marquart, Kim Fabiano, Allam, Ahmed, Krauthammer, Michael, Schwank, Gerald
Format:	Journal Article
Language:	English
Published:	England 14.08.2025
ISSN:	1750-2799, 1750-2799
Online Access:	Get more information
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