A signal on-off ratiometric electrochemical sensing platform coupled with a molecularly imprinted polymer and CuCo2O4/NCNTs signal amplification for selective determination of gemcitabine
A novel and reliable electrochemical analysis tool was developed for gemcitabine (GEM) detection by combining the selective recognition of molecular imprinted polymer (MIP) technology and ratiometric quantification strategy. In this contribution, a glassy carbon electrode (GCE) surface was first mod...
Uložené v:
| Vydané v: | Sensors and actuators. B, Chemical Ročník 371; s. 132552 |
|---|---|
| Hlavní autori: | , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
Lausanne
Elsevier B.V
15.11.2022
Elsevier Science Ltd |
| Predmet: | |
| ISSN: | 0925-4005, 1873-3077 |
| On-line prístup: | Získať plný text |
| Tagy: |
Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
|
| Abstract | A novel and reliable electrochemical analysis tool was developed for gemcitabine (GEM) detection by combining the selective recognition of molecular imprinted polymer (MIP) technology and ratiometric quantification strategy. In this contribution, a glassy carbon electrode (GCE) surface was first modified by drop-coating CuCo2O4/NCNTs and ferrocene (FC) to achieve a ratiometric on-off response (CuCo2O4/NCNTs/FC was served as a substrate to amplify signal and to provide reference signal). Then, MIP network was prepared through in situ electrochemical polymerization, using aniline as monomer and GEM as template. Differential pulse voltammetry (DPV) analysis showed that the oxidation peak signal of FC decreased with the increase of GEM concentration, whereas the oxidation peak signal of GEM increased. Therefore, the peak current ratio of IGEM/IFC was employed to accurately reflect the concentration of GEM. Using this method, GEM was measured in the range from 0.1 to 150 µM with a low limit of detection of 11.3 nM. In addition, the sensor showed high reproducibility, anti-interference ability and good stability for 6 weeks toward GEM detection. Finally, the proposed sensor exhibited excellent detection performance in complex pharmaceutical and biological matrices with satisfactory recoveries.
•A molecular imprinting ratiometric electrochemical sensor is developed for the detection of gemcitabine.•The CuCo2O4/NCNTs nanocomposite is applied to amplify the signal.•The sensor exhibits excellent gemcitabine sensing performance in complex pharmaceutical and biological matrices. |
|---|---|
| AbstractList | A novel and reliable electrochemical analysis tool was developed for gemcitabine (GEM) detection by combining the selective recognition of molecular imprinted polymer (MIP) technology and ratiometric quantification strategy. In this contribution, a glassy carbon electrode (GCE) surface was first modified by drop-coating CuCo2O4/NCNTs and ferrocene (FC) to achieve a ratiometric on-off response (CuCo2O4/NCNTs/FC was served as a substrate to amplify signal and to provide reference signal). Then, MIP network was prepared through in situ electrochemical polymerization, using aniline as monomer and GEM as template. Differential pulse voltammetry (DPV) analysis showed that the oxidation peak signal of FC decreased with the increase of GEM concentration, whereas the oxidation peak signal of GEM increased. Therefore, the peak current ratio of IGEM/IFC was employed to accurately reflect the concentration of GEM. Using this method, GEM was measured in the range from 0.1 to 150 µM with a low limit of detection of 11.3 nM. In addition, the sensor showed high reproducibility, anti-interference ability and good stability for 6 weeks toward GEM detection. Finally, the proposed sensor exhibited excellent detection performance in complex pharmaceutical and biological matrices with satisfactory recoveries.
•A molecular imprinting ratiometric electrochemical sensor is developed for the detection of gemcitabine.•The CuCo2O4/NCNTs nanocomposite is applied to amplify the signal.•The sensor exhibits excellent gemcitabine sensing performance in complex pharmaceutical and biological matrices. A novel and reliable electrochemical analysis tool was developed for gemcitabine (GEM) detection by combining the selective recognition of molecular imprinted polymer (MIP) technology and ratiometric quantification strategy. In this contribution, a glassy carbon electrode (GCE) surface was first modified by drop-coating CuCo2O4/NCNTs and ferrocene (FC) to achieve a ratiometric on-off response (CuCo2O4/NCNTs/FC was served as a substrate to amplify signal and to provide reference signal). Then, MIP network was prepared through in situ electrochemical polymerization, using aniline as monomer and GEM as template. Differential pulse voltammetry (DPV) analysis showed that the oxidation peak signal of FC decreased with the increase of GEM concentration, whereas the oxidation peak signal of GEM increased. Therefore, the peak current ratio of IGEM/IFC was employed to accurately reflect the concentration of GEM. Using this method, GEM was measured in the range from 0.1 to 150 µM with a low limit of detection of 11.3 nM. In addition, the sensor showed high reproducibility, anti-interference ability and good stability for 6 weeks toward GEM detection. Finally, the proposed sensor exhibited excellent detection performance in complex pharmaceutical and biological matrices with satisfactory recoveries. |
| ArticleNumber | 132552 |
| Author | Sadeghian, Reihaneh Hatamluyi, Behnaz Boroushaki, Mohammad Taher Sadeghzadeh, Samira Mirimoghaddam, Mohammad Mobin |
| Author_xml | – sequence: 1 givenname: Behnaz surname: Hatamluyi fullname: Hatamluyi, Behnaz organization: Department of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran – sequence: 2 givenname: Samira surname: Sadeghzadeh fullname: Sadeghzadeh, Samira organization: Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran – sequence: 3 givenname: Reihaneh surname: Sadeghian fullname: Sadeghian, Reihaneh organization: Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran – sequence: 4 givenname: Mohammad Mobin surname: Mirimoghaddam fullname: Mirimoghaddam, Mohammad Mobin organization: Medical Doctor, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran – sequence: 5 givenname: Mohammad Taher surname: Boroushaki fullname: Boroushaki, Mohammad Taher email: Boroushakimt@mums.ac.ir organization: Department of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran |
| BookMark | eNp9kUtv3CAUhVGVSp2k_QHdIXXtCeAHY3UVWX1JUbJJ1wjD9YQRDxdwqvlt-XPFcrPJIisW9373HM65RBc-eEDoMyV7Smh3fdonP-4ZYWxPa9a27B3a0QOvq5pwfoF2pGdt1RDSfkCXKZ0IIU3dkR16vsHJHL20OPgqTBOOMpvgIEejMFhQOQb1CM6ospLAJ-OPeLYyTyE6rMIyW9D4r8mPWGIXCrBYGe0ZGzdH43MZzsGeHUQsvcbDMgR231zfDXcP6UVZutmaqSgUZY_L4SK0KpsnwBoyRGf8NgsTPoJTJsvRePiI3k_SJvj0_71Cv79_exh-Vrf3P34NN7eVKkHkijNoQfZd17XjWNMDlXyc-mbkfOo1J4yzjkpgjIMmvdZtrRvo5GFs1ahUB6q-Ql-2u3MMfxZIWZzCEovzJBivG04b1tOyxbctFUNKESax-lxt5yiNFZSItSlxEqUpsTYltqYKSV-RJTon4_lN5uvGQPn4k4EokjLgFWgTS3RCB_MG_Q-2lLLH |
| CitedBy_id | crossref_primary_10_1016_j_aca_2024_342876 crossref_primary_10_1016_j_electacta_2023_143672 crossref_primary_10_1016_j_matchemphys_2023_128117 crossref_primary_10_1016_j_foodchem_2023_136927 crossref_primary_10_1016_j_jfca_2022_105003 crossref_primary_10_1016_j_talanta_2023_124423 crossref_primary_10_1016_j_talanta_2023_124632 crossref_primary_10_1080_10408347_2023_2301652 crossref_primary_10_1002_open_202500180 crossref_primary_10_1016_j_molliq_2025_127889 crossref_primary_10_1007_s00604_024_06649_x crossref_primary_10_1016_j_microc_2023_109186 crossref_primary_10_1007_s10876_024_02682_1 crossref_primary_10_1016_j_microc_2024_110522 crossref_primary_10_1016_j_mser_2024_100840 crossref_primary_10_1088_1361_6528_acfb0d crossref_primary_10_1016_j_cej_2024_156315 crossref_primary_10_1016_j_microc_2025_113048 crossref_primary_10_1016_j_snb_2023_133424 crossref_primary_10_1016_j_talanta_2023_125233 crossref_primary_10_3390_molecules28227552 crossref_primary_10_1016_j_mseb_2023_117109 crossref_primary_10_1016_j_microc_2024_111094 |
| Cites_doi | 10.1016/j.aca.2018.03.036 10.1016/j.electacta.2018.07.068 10.1016/j.jelechem.2009.09.018 10.1016/j.snb.2015.12.050 10.1016/j.farmac.2004.01.013 10.1016/j.snb.2018.07.138 10.1016/j.jelechem.2017.08.032 10.1016/j.snb.2022.131582 10.1016/j.microc.2022.107319 10.1016/j.jelechem.2017.04.032 10.1016/j.jelechem.2021.115374 10.1016/j.jchromb.2006.03.023 10.1016/j.msec.2016.07.025 10.1186/s13069-015-0020-2 10.1016/j.bios.2019.111483 10.1016/j.talanta.2016.03.049 10.1016/j.bios.2019.03.054 10.1016/j.jchromb.2007.08.018 10.1016/j.bios.2019.111611 10.1016/j.snb.2007.04.034 10.1016/j.bios.2018.12.002 10.1039/C9NA00455F 10.1016/j.snb.2019.02.017 10.1016/j.cclet.2016.11.028 10.1016/j.snb.2019.127614 10.1016/j.snb.2015.09.154 10.1039/C8AN00111A 10.1016/j.snb.2020.128219 10.1016/j.bioelechem.2009.07.012 10.1016/j.foodchem.2021.129782 10.1016/j.bios.2022.114209 10.1016/j.snb.2012.11.103 10.1016/j.aca.2021.339245 10.1016/j.jchromb.2006.04.036 10.1016/j.snb.2014.04.094 10.1016/j.jiec.2013.02.040 10.1016/j.molliq.2018.06.105 10.1016/j.bios.2017.08.058 10.1016/j.bios.2022.114203 10.1016/j.talanta.2015.01.013 10.1016/j.bios.2020.112091 10.1016/j.jchromb.2009.06.002 10.1016/j.talanta.2021.122662 10.1021/acssuschemeng.8b04179 |
| ContentType | Journal Article |
| Copyright | 2022 Elsevier B.V. Copyright Elsevier Science Ltd. Nov 15, 2022 |
| Copyright_xml | – notice: 2022 Elsevier B.V. – notice: Copyright Elsevier Science Ltd. Nov 15, 2022 |
| DBID | AAYXX CITATION 7SP 7SR 7TB 7U5 8BQ 8FD FR3 JG9 L7M |
| DOI | 10.1016/j.snb.2022.132552 |
| DatabaseName | CrossRef Electronics & Communications Abstracts Engineered Materials Abstracts Mechanical & Transportation Engineering Abstracts Solid State and Superconductivity Abstracts METADEX Technology Research Database Engineering Research Database Materials Research Database Advanced Technologies Database with Aerospace |
| DatabaseTitle | CrossRef Materials Research Database Engineered Materials Abstracts Technology Research Database Mechanical & Transportation Engineering Abstracts Electronics & Communications Abstracts Solid State and Superconductivity Abstracts Engineering Research Database Advanced Technologies Database with Aerospace METADEX |
| DatabaseTitleList | Materials Research Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Engineering |
| EISSN | 1873-3077 |
| ExternalDocumentID | 10_1016_j_snb_2022_132552 S0925400522011959 |
| GroupedDBID | --K --M -~X .~1 0R~ 123 1B1 1RT 1~. 1~5 4.4 457 4G. 53G 5VS 7-5 71M 8P~ 9JN AABNK AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AARLI AAXUO ABFNM ABMAC ABYKQ ACDAQ ACGFS ACRLP ADBBV ADECG ADEZE ADTZH AEBSH AECPX AEKER AFKWA AFTJW AFZHZ AGHFR AGUBO AGYEJ AHHHB AHJVU AIEXJ AIKHN AITUG AJOXV AJSZI ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ AXJTR BJAXD BKOJK BLXMC CS3 EBS EFJIC EFLBG EO8 EO9 EP2 EP3 F5P FDB FIRID FLBIZ FNPLU FYGXN G-Q GBLVA IHE J1W JJJVA KOM M36 M41 MO0 N9A O-L O9- OAUVE OZT P-8 P-9 PC. Q38 RNS ROL RPZ SCC SDF SDG SDP SES SPC SPCBC SSK SST SSZ T5K TN5 YK3 ~G- 9DU AAQXK AATTM AAXKI AAYWO AAYXX ABWVN ABXDB ACLOT ACNNM ACRPL ADMUD ADNMO AEIPS AFJKZ AGQPQ AIIUN AJQLL ANKPU APXCP ASPBG AVWKF AZFZN CITATION EFKBS EJD FEDTE FGOYB HMU HVGLF HZ~ R2- SCB SCH SEW WUQ ~HD 7SP 7SR 7TB 7U5 8BQ 8FD FR3 JG9 L7M |
| ID | FETCH-LOGICAL-c255t-72e5ea96665bb3181a7bf94b77f9d7027261ae227ed09dd53d4e6a8b5cbcc6ec3 |
| ISICitedReferencesCount | 26 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000862175900007&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0925-4005 |
| IngestDate | Sun Nov 09 08:03:19 EST 2025 Sat Nov 29 07:10:35 EST 2025 Tue Nov 18 22:28:02 EST 2025 Fri Feb 23 02:37:33 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | CuCo2O4 Gemcitabine Ratiometric electrochemical sensor Nitrogen-doped carbon nanotubes Molecularly imprinted polymer |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c255t-72e5ea96665bb3181a7bf94b77f9d7027261ae227ed09dd53d4e6a8b5cbcc6ec3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 |
| PQID | 2734714291 |
| PQPubID | 2047454 |
| ParticipantIDs | proquest_journals_2734714291 crossref_citationtrail_10_1016_j_snb_2022_132552 crossref_primary_10_1016_j_snb_2022_132552 elsevier_sciencedirect_doi_10_1016_j_snb_2022_132552 |
| PublicationCentury | 2000 |
| PublicationDate | 2022-11-15 |
| PublicationDateYYYYMMDD | 2022-11-15 |
| PublicationDate_xml | – month: 11 year: 2022 text: 2022-11-15 day: 15 |
| PublicationDecade | 2020 |
| PublicationPlace | Lausanne |
| PublicationPlace_xml | – name: Lausanne |
| PublicationTitle | Sensors and actuators. B, Chemical |
| PublicationYear | 2022 |
| Publisher | Elsevier B.V Elsevier Science Ltd |
| Publisher_xml | – name: Elsevier B.V – name: Elsevier Science Ltd |
| References | Khoury, Deroussent, Reddy, Couvreur, Vassal, Paci (bib9) 2007; 858 Nezhadali, Sadeghzadeh (bib32) 2016; 224 Shoja, Kermanpur, Karimzadeh, Ghodsi, Rafati, Adhami (bib1) 2019; 145 Nezhadali, Shadmehri (bib19) 2014; 202 Hatamluyi, Sadeghian, Malek, Boroushaki (bib29) 2021; 357 Sun, Xu, Chen (bib34) 2021; 7 Yang, Yu, Yan, Zeng, Luo, Liu, Morrin, Luo, Li (bib13) 2018; 274 Hatamluyi, Rezayi, Amel Jamehdar, Rizi, Mojarrad, Meshkat, Choobin, Soleimanpour, Boroushaki (bib37) 2022; 207 Tandel, Teradal, Satpati, Jaldappagari (bib42) 2017; 28 Bartold, Iskierko, Borowicz, Noworyta, Lin, Kalecki, Sharma, Lin, Kutner (bib25) 2022; 208 Hatamluyi, Es'haghi (bib45) 2018; 283 Hatamluyi, Sadeghian, Sany, Alipourfard, Rezayi (bib21) 2021; 234 Li, Zhang, Dang, Chen, Zhang, Li, Ye (bib23) 2019; 127 Wang, Cheng, Liu, Ding, Zou, Wang, Zhao, Rao (bib41) 2018; 6 Zhang, Liu, Han, Wei, Xu, Zou, Zhang, Chen (bib12) 2020; 154 Yang, Hu, Li (bib16) 2019; 135 Nezhadali, Sadeghzadeh (bib20) 2017; 795 Hatamluyi, Rezayi, Beheshti, Boroushaki (bib22) 2020; 318 Gui, Guo, Jin (bib31) 2019; 1 Wan, Shen, Xu, Xu, Zhang, Sun, Zhang, Yin, Wang (bib35) 2021; 895 Kalanur, Katrahalli, Seetharamappa (bib44) 2009; 636 Najafi, Amani, Shahlaei (bib4) 2018; 266 Losa, Sierra, Gión, Esteban, Buesa (bib6) 2006; 840 Wang, Yao, Liu, Cheng, Liu, Liu, Sun, Zhao, Ding, Lu, Zou, Wang, Zhao, Rao (bib33) 2019; 142 Hatamluyi, Hashemzadeh, Darroudi (bib28) 2020; 307 Bowen, Wang, Licea-Perez (bib10) 2009; 877 Li, Kan (bib15) 2018; 143 Özcan, Şahin (bib18) 2007; 127 Jin, Zhao, Gui, Gao, Wang (bib36) 2018; 1025 Liu, Hu, Xia, Zhao, Zeng (bib14) 2022; 1190 Hatamluyi, Es'haghi, Modarres Zahed, Darroudi (bib27) 2019; 286 Kaarteenaho, Lappi-Blanco (bib24) 2015; 8 Yang, Sun, Jin, Gui (bib17) 2022; 177 Chen, Lv, Zhang, Zhao, Sun (bib11) 2016; 227 Hu, Xia, Liu, Chen, Zeng (bib26) 2022; 359 Naik, Nandibewoor (bib3) 2013; 19 Nezhadali, Shadmehri (bib40) 2013; 177 Tığ, Zeybek, Pekyardımcı (bib2) 2016; 154 Kirstein, Hassan, Guire, Weller, Dagit, Fisher, Remmel (bib7) 2006; 835 Gui, Jin, Guo, Wang (bib30) 2018; 100 Shah, Diculescu, Qureshi, Oliveira-Brett (bib43) 2010; 77 Hatamluyi, Es'haghi (bib39) 2017; 801 Daneshvar, Rounaghi, Es'haghi, Chamsaz, Tarahomi (bib38) 2016; 69 Florea, Guo, Cristea, Bessueille, Vocanson, Goutaland, Dzyadevych, Săndulescu, Jaffrezic-Renault (bib5) 2015; 138 Yılmaz, Kadıoğlu (bib8) 2004; 59 Shoja (10.1016/j.snb.2022.132552_bib1) 2019; 145 Kalanur (10.1016/j.snb.2022.132552_bib44) 2009; 636 Wang (10.1016/j.snb.2022.132552_bib41) 2018; 6 Li (10.1016/j.snb.2022.132552_bib15) 2018; 143 Yang (10.1016/j.snb.2022.132552_bib17) 2022; 177 Daneshvar (10.1016/j.snb.2022.132552_bib38) 2016; 69 Hatamluyi (10.1016/j.snb.2022.132552_bib22) 2020; 318 Wan (10.1016/j.snb.2022.132552_bib35) 2021; 895 Zhang (10.1016/j.snb.2022.132552_bib12) 2020; 154 Shah (10.1016/j.snb.2022.132552_bib43) 2010; 77 Tandel (10.1016/j.snb.2022.132552_bib42) 2017; 28 Hatamluyi (10.1016/j.snb.2022.132552_bib45) 2018; 283 Özcan (10.1016/j.snb.2022.132552_bib18) 2007; 127 Hatamluyi (10.1016/j.snb.2022.132552_bib37) 2022; 207 Gui (10.1016/j.snb.2022.132552_bib31) 2019; 1 Liu (10.1016/j.snb.2022.132552_bib14) 2022; 1190 Wang (10.1016/j.snb.2022.132552_bib33) 2019; 142 Florea (10.1016/j.snb.2022.132552_bib5) 2015; 138 Tığ (10.1016/j.snb.2022.132552_bib2) 2016; 154 Bartold (10.1016/j.snb.2022.132552_bib25) 2022; 208 Naik (10.1016/j.snb.2022.132552_bib3) 2013; 19 Kirstein (10.1016/j.snb.2022.132552_bib7) 2006; 835 Sun (10.1016/j.snb.2022.132552_bib34) 2021; 7 Bowen (10.1016/j.snb.2022.132552_bib10) 2009; 877 Yang (10.1016/j.snb.2022.132552_bib16) 2019; 135 Hatamluyi (10.1016/j.snb.2022.132552_bib39) 2017; 801 Nezhadali (10.1016/j.snb.2022.132552_bib32) 2016; 224 Hatamluyi (10.1016/j.snb.2022.132552_bib28) 2020; 307 Yang (10.1016/j.snb.2022.132552_bib13) 2018; 274 Hatamluyi (10.1016/j.snb.2022.132552_bib29) 2021; 357 Li (10.1016/j.snb.2022.132552_bib23) 2019; 127 Jin (10.1016/j.snb.2022.132552_bib36) 2018; 1025 Yılmaz (10.1016/j.snb.2022.132552_bib8) 2004; 59 Kaarteenaho (10.1016/j.snb.2022.132552_bib24) 2015; 8 Gui (10.1016/j.snb.2022.132552_bib30) 2018; 100 Najafi (10.1016/j.snb.2022.132552_bib4) 2018; 266 Losa (10.1016/j.snb.2022.132552_bib6) 2006; 840 Chen (10.1016/j.snb.2022.132552_bib11) 2016; 227 Hu (10.1016/j.snb.2022.132552_bib26) 2022; 359 Nezhadali (10.1016/j.snb.2022.132552_bib19) 2014; 202 Nezhadali (10.1016/j.snb.2022.132552_bib40) 2013; 177 Hatamluyi (10.1016/j.snb.2022.132552_bib21) 2021; 234 Khoury (10.1016/j.snb.2022.132552_bib9) 2007; 858 Nezhadali (10.1016/j.snb.2022.132552_bib20) 2017; 795 Hatamluyi (10.1016/j.snb.2022.132552_bib27) 2019; 286 |
| References_xml | – volume: 135 start-page: 224 year: 2019 end-page: 230 ident: bib16 article-title: Molecularly imprinted polymer-decorated signal on-off ratiometric electrochemical sensor for selective and robust dopamine detection publication-title: Biosens. Bioelectron. – volume: 127 start-page: 362 year: 2007 end-page: 369 ident: bib18 article-title: Determination of paracetamol based on electropolymerized-molecularly imprinted polypyrrole modified pencil graphite electrode publication-title: Sens. Actuators B. – volume: 100 start-page: 56 year: 2018 end-page: 70 ident: bib30 article-title: Recent advances and future prospects in molecularly imprinted polymers-based electrochemical biosensors publication-title: Biosens. Bioelectron. – volume: 895 year: 2021 ident: bib35 article-title: Ferrocene-functionalized Ni(II)-based metal-organic framework as electrochemical sensing interface for ratiometric analysis of Cu publication-title: J. Electroanal. Chem. – volume: 1 start-page: 3325 year: 2019 end-page: 3363 ident: bib31 article-title: Preparation and applications of electrochemical chemosensors based on carbon-nanomaterial-modified molecularly imprinted polymers publication-title: Nanoscale Adv. – volume: 636 start-page: 93 year: 2009 end-page: 100 ident: bib44 article-title: Electrochemical studies and spectroscopic investigations on the interaction of an anticancer drug with DNA and their analytical applications publication-title: J. Electroanal. Chem. – volume: 286 start-page: 540 year: 2019 end-page: 549 ident: bib27 article-title: A novel electrochemical sensor based on GQDs-PANI/ZnO-NCs modified glassy carbon electrode for simultaneous determination of Irinotecan and 5-Fluorouracil in biological samples publication-title: Sens. Actuators B. – volume: 177 start-page: 871 year: 2013 end-page: 878 ident: bib40 article-title: Computer-aided sensor design and analysis of thiocarbohydrazide in biological matrices using electropolymerized-molecularly imprinted polypyrrole modified pencil graphite electrode publication-title: Sens. Actuators B. – volume: 28 start-page: 1429 year: 2017 end-page: 1437 ident: bib42 article-title: Fabrication of the electrochemically reduced graphene oxide-bismuth nanoparticles composite and its analytical application for an anticancer drug gemcitabine publication-title: Chin. Chem. Lett. – volume: 318 year: 2020 ident: bib22 article-title: Ultra-sensitive molecularly imprinted electrochemical sensor for patulin detection based on a novel assembling strategy using Au@Cu-MOF/N-GQDs publication-title: Sens. Actuators B. – volume: 145 year: 2019 ident: bib1 article-title: Electrochemical molecularly bioimprinted siloxane biosensor on the basis of core/shell silver nanoparticles/EGFR exon 21 L858R point mutant gene/siloxane film for ultra-sensing of Gemcitabine as a lung cancer chemotherapy medication publication-title: Biosens. Bioelectron. – volume: 59 start-page: 425 year: 2004 end-page: 429 ident: bib8 article-title: Comparison of zero- and second-order derivative spectrophotometric and HPLC methods for the determination of gemcitabine in human plasma publication-title: Il Farm. – volume: 207 year: 2022 ident: bib37 article-title: Sensitive and specific clinically diagnosis of SARS-CoV-2 employing a novel biosensor based on boron nitride quantum dots/flower-like gold nanostructures signal amplification publication-title: Biosens. Bioelectron. – volume: 208 year: 2022 ident: bib25 article-title: Molecularly imprinted polymer-based extended-gate field-effect transistor (EG-FET) chemosensor for selective determination of matrix metalloproteinase-1 (MMP-1) protein publication-title: Biosens. Bioelectron. – volume: 359 year: 2022 ident: bib26 article-title: An effective ratiometric electrochemical sensor for highly selective and reproducible detection of ochratoxin A: use of magnetic field improved molecularly imprinted polymer publication-title: Sens. Actuators B. – volume: 1025 start-page: 154 year: 2018 end-page: 162 ident: bib36 article-title: Reduced graphene oxide/nile blue/gold nanoparticles complex-modified glassy carbon electrode used as a sensitive and label-free aptasensor for ratiometric electrochemical sensing of dopamine publication-title: Anal. Chim. Acta – volume: 274 start-page: 501 year: 2018 end-page: 516 ident: bib13 article-title: A review of ratiometric electrochemical sensors: from design schemes to future prospects publication-title: Sens. Actuators B – volume: 154 start-page: 312 year: 2016 end-page: 321 ident: bib2 article-title: Electrochemical DNA biosensor based on poly(2,6-pyridinedicarboxylic acid) modified glassy carbon electrode for the determination of anticancer drug gemcitabine publication-title: Talanta – volume: 77 start-page: 145 year: 2010 end-page: 150 ident: bib43 article-title: Electrochemical behaviour of dimethyl-2-oxoglutarate on glassy carbon electrode publication-title: Bioelectrochemistry – volume: 154 year: 2020 ident: bib12 article-title: A signal on-off ratiometric electrochemical sensor coupled with a molecular imprinted polymer for selective and stable determination of imidacloprid publication-title: Biosens. Bioelectron. – volume: 283 start-page: 1170 year: 2018 end-page: 1177 ident: bib45 article-title: Electrochemical biosensing platform based on molecularly imprinted polymer reinforced by ZnO–graphene capped quantum dots for 6-mercaptopurine detection publication-title: Electrochim. Acta – volume: 177 year: 2022 ident: bib17 article-title: Sulfur nanoparticle-encapsulated MOF and boron nanosheet-ferrocene complex modified electrode platform for ratiometric electrochemical sensing of adriamycin and real-time monitoring of drug release publication-title: Microchem. J. – volume: 357 year: 2021 ident: bib29 article-title: Improved solid phase extraction for selective and efficient quantification of sunset yellow in different food samples using a novel molecularly imprinted polymer reinforced by Fe publication-title: Food Chem. – volume: 69 start-page: 653 year: 2016 end-page: 660 ident: bib38 article-title: Fabrication a new modified electrochemical sensor based on Au–Pd bimetallic nanoparticle decorated graphene for citalopram determination publication-title: Mater. Sci. Eng. C – volume: 307 year: 2020 ident: bib28 article-title: A novel molecularly imprinted polymer decorated by CQDs@HBNNS nanocomposite and UiO-66-NH2 for ultra-selective electrochemical sensing of Oxaliplatin in biological samples publication-title: Sens. Actuators B. – volume: 127 start-page: 207 year: 2019 end-page: 214 ident: bib23 article-title: A robust electrochemical sensing of molecularly imprinted polymer prepared by using bifunctional monomer and its application in detection of cypermethrin publication-title: Biosens. Bioelectron. – volume: 1190 year: 2022 ident: bib14 article-title: A novel ratiometric electrochemical sensor based on dual-monomer molecularly imprinted polymer and Pt/Co3O4 for sensitive detection of chlorpromazine hydrochloride publication-title: Anal. Chim. Acta – volume: 795 start-page: 32 year: 2017 end-page: 40 ident: bib20 article-title: Experimental design-artificial neural network-genetic algorithm optimization and computer-assisted design of celecoxib molecularly imprinted polymer/carbon nanotube sensor publication-title: J. Electroanal. Chem. – volume: 227 start-page: 43 year: 2016 end-page: 47 ident: bib11 article-title: A simple but efficient electrochemical method to assay protein arginine deiminase 4 publication-title: Sens. Actuators B – volume: 6 start-page: 16847 year: 2018 end-page: 16858 ident: bib41 article-title: C3N4 nanosheets/metal–organic framework wrapped with molecularly imprinted polymer sensor: fabrication, characterization, and electrochemical detection of furosemide publication-title: ACS Sustain. Chem. Eng. – volume: 138 start-page: 71 year: 2015 end-page: 76 ident: bib5 article-title: Anticancer drug detection using a highly sensitive molecularly imprinted electrochemical sensor based on an electropolymerized microporous metal organic framework publication-title: Talanta – volume: 840 start-page: 44 year: 2006 end-page: 49 ident: bib6 article-title: Simultaneous determination of gemcitabine di- and triphosphate in human blood mononuclear and cancer cells by RP-HPLC and UV detection publication-title: J. Chromatogr. B – volume: 202 start-page: 240 year: 2014 end-page: 251 ident: bib19 article-title: Neuro-genetic multi-objective optimization and computer-aided design of pantoprazole molecularly imprinted polypyrrole sensor publication-title: Sens. Actuators B. – volume: 224 start-page: 134 year: 2016 end-page: 142 ident: bib32 article-title: Optimization of stripping voltammetric sensor by mixture design-artificial neural network-genetic algorithm for determination of trace copper(II) based on iodoquinol-carbon nanotube modified carbon paste electrode publication-title: Sens. Actuators B. – volume: 143 start-page: 2150 year: 2018 end-page: 2156 ident: bib15 article-title: A ratiometric strategy -based electrochemical sensing interface for the sensitive and reliable detection of imidacloprid publication-title: Analyst – volume: 801 start-page: 439 year: 2017 end-page: 449 ident: bib39 article-title: A layer-by-layer sensing architecture based on dendrimer and ionic liquid supported reduced graphene oxide for simultaneous hollow-fiber solid phase microextraction and electrochemical determination of anti-cancer drug imatinib in biological samples publication-title: J. Electroanal. Chem. – volume: 858 start-page: 71 year: 2007 end-page: 78 ident: bib9 article-title: Simultaneous determination of gemcitabine and gemcitabine-squalene by liquid chromatography–tandem mass spectrometry in human plasma publication-title: J. Chromatogr. B – volume: 234 year: 2021 ident: bib21 article-title: Dual-signaling electrochemical ratiometric strategy for simultaneous quantification of anticancer drugs publication-title: Talanta – volume: 19 start-page: 1933 year: 2013 end-page: 1938 ident: bib3 article-title: Electro-oxidation and determination of gemcitabine hydrochloride, an anticancer drug at gold electrode publication-title: J. Ind. Eng. Chem. – volume: 8 start-page: 3 year: 2015 ident: bib24 article-title: Tissue is an issue in the search for biomarkers in idiopathic pulmonary fibrosis publication-title: Fibrogen. Tissue Repair – volume: 877 start-page: 2123 year: 2009 end-page: 2129 ident: bib10 article-title: Development of a sensitive and selective LC–MS/MS method for simultaneous determination of gemcitabine and 2,2-difluoro-2-deoxyuridine in human plasma publication-title: J. Chromatogr. B – volume: 142 year: 2019 ident: bib33 article-title: CuCo2O4/N-Doped CNTs loaded with molecularly imprinted polymer for electrochemical sensor: preparation, characterization and detection of metronidazole publication-title: Biosens. Bioelectron. – volume: 266 start-page: 514 year: 2018 end-page: 521 ident: bib4 article-title: Rapid determination of the anti-cancer agent Gemcitabine in biological samples by fluorescence sensor based on Au-doped CdTe publication-title: J. Mol. Liq. – volume: 7 start-page: 98 year: 2021 end-page: 126 ident: bib34 article-title: A review on the synthesis of CuCo2O4-based electrode materials and their applications in supercapacitors publication-title: J. Mater. – volume: 835 start-page: 136 year: 2006 end-page: 142 ident: bib7 article-title: High-performance liquid chromatographic method for the determination of gemcitabine and 2′,2′-difluorodeoxyuridine in plasma and tissue culture media publication-title: J. Chromatogr. B – volume: 1025 start-page: 154 year: 2018 ident: 10.1016/j.snb.2022.132552_bib36 article-title: Reduced graphene oxide/nile blue/gold nanoparticles complex-modified glassy carbon electrode used as a sensitive and label-free aptasensor for ratiometric electrochemical sensing of dopamine publication-title: Anal. Chim. Acta doi: 10.1016/j.aca.2018.03.036 – volume: 283 start-page: 1170 year: 2018 ident: 10.1016/j.snb.2022.132552_bib45 article-title: Electrochemical biosensing platform based on molecularly imprinted polymer reinforced by ZnO–graphene capped quantum dots for 6-mercaptopurine detection publication-title: Electrochim. Acta doi: 10.1016/j.electacta.2018.07.068 – volume: 636 start-page: 93 year: 2009 ident: 10.1016/j.snb.2022.132552_bib44 article-title: Electrochemical studies and spectroscopic investigations on the interaction of an anticancer drug with DNA and their analytical applications publication-title: J. Electroanal. Chem. doi: 10.1016/j.jelechem.2009.09.018 – volume: 227 start-page: 43 year: 2016 ident: 10.1016/j.snb.2022.132552_bib11 article-title: A simple but efficient electrochemical method to assay protein arginine deiminase 4 publication-title: Sens. Actuators B doi: 10.1016/j.snb.2015.12.050 – volume: 59 start-page: 425 year: 2004 ident: 10.1016/j.snb.2022.132552_bib8 article-title: Comparison of zero- and second-order derivative spectrophotometric and HPLC methods for the determination of gemcitabine in human plasma publication-title: Il Farm. doi: 10.1016/j.farmac.2004.01.013 – volume: 274 start-page: 501 year: 2018 ident: 10.1016/j.snb.2022.132552_bib13 article-title: A review of ratiometric electrochemical sensors: from design schemes to future prospects publication-title: Sens. Actuators B doi: 10.1016/j.snb.2018.07.138 – volume: 801 start-page: 439 year: 2017 ident: 10.1016/j.snb.2022.132552_bib39 article-title: A layer-by-layer sensing architecture based on dendrimer and ionic liquid supported reduced graphene oxide for simultaneous hollow-fiber solid phase microextraction and electrochemical determination of anti-cancer drug imatinib in biological samples publication-title: J. Electroanal. Chem. doi: 10.1016/j.jelechem.2017.08.032 – volume: 359 year: 2022 ident: 10.1016/j.snb.2022.132552_bib26 article-title: An effective ratiometric electrochemical sensor for highly selective and reproducible detection of ochratoxin A: use of magnetic field improved molecularly imprinted polymer publication-title: Sens. Actuators B. doi: 10.1016/j.snb.2022.131582 – volume: 177 year: 2022 ident: 10.1016/j.snb.2022.132552_bib17 article-title: Sulfur nanoparticle-encapsulated MOF and boron nanosheet-ferrocene complex modified electrode platform for ratiometric electrochemical sensing of adriamycin and real-time monitoring of drug release publication-title: Microchem. J. doi: 10.1016/j.microc.2022.107319 – volume: 795 start-page: 32 year: 2017 ident: 10.1016/j.snb.2022.132552_bib20 article-title: Experimental design-artificial neural network-genetic algorithm optimization and computer-assisted design of celecoxib molecularly imprinted polymer/carbon nanotube sensor publication-title: J. Electroanal. Chem. doi: 10.1016/j.jelechem.2017.04.032 – volume: 895 year: 2021 ident: 10.1016/j.snb.2022.132552_bib35 article-title: Ferrocene-functionalized Ni(II)-based metal-organic framework as electrochemical sensing interface for ratiometric analysis of Cu2+, Pb2+ and Cd2+ publication-title: J. Electroanal. Chem. doi: 10.1016/j.jelechem.2021.115374 – volume: 835 start-page: 136 year: 2006 ident: 10.1016/j.snb.2022.132552_bib7 article-title: High-performance liquid chromatographic method for the determination of gemcitabine and 2′,2′-difluorodeoxyuridine in plasma and tissue culture media publication-title: J. Chromatogr. B doi: 10.1016/j.jchromb.2006.03.023 – volume: 69 start-page: 653 year: 2016 ident: 10.1016/j.snb.2022.132552_bib38 article-title: Fabrication a new modified electrochemical sensor based on Au–Pd bimetallic nanoparticle decorated graphene for citalopram determination publication-title: Mater. Sci. Eng. C doi: 10.1016/j.msec.2016.07.025 – volume: 8 start-page: 3 year: 2015 ident: 10.1016/j.snb.2022.132552_bib24 article-title: Tissue is an issue in the search for biomarkers in idiopathic pulmonary fibrosis publication-title: Fibrogen. Tissue Repair doi: 10.1186/s13069-015-0020-2 – volume: 142 year: 2019 ident: 10.1016/j.snb.2022.132552_bib33 article-title: CuCo2O4/N-Doped CNTs loaded with molecularly imprinted polymer for electrochemical sensor: preparation, characterization and detection of metronidazole publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2019.111483 – volume: 154 start-page: 312 year: 2016 ident: 10.1016/j.snb.2022.132552_bib2 article-title: Electrochemical DNA biosensor based on poly(2,6-pyridinedicarboxylic acid) modified glassy carbon electrode for the determination of anticancer drug gemcitabine publication-title: Talanta doi: 10.1016/j.talanta.2016.03.049 – volume: 135 start-page: 224 year: 2019 ident: 10.1016/j.snb.2022.132552_bib16 article-title: Molecularly imprinted polymer-decorated signal on-off ratiometric electrochemical sensor for selective and robust dopamine detection publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2019.03.054 – volume: 858 start-page: 71 year: 2007 ident: 10.1016/j.snb.2022.132552_bib9 article-title: Simultaneous determination of gemcitabine and gemcitabine-squalene by liquid chromatography–tandem mass spectrometry in human plasma publication-title: J. Chromatogr. B doi: 10.1016/j.jchromb.2007.08.018 – volume: 145 year: 2019 ident: 10.1016/j.snb.2022.132552_bib1 article-title: Electrochemical molecularly bioimprinted siloxane biosensor on the basis of core/shell silver nanoparticles/EGFR exon 21 L858R point mutant gene/siloxane film for ultra-sensing of Gemcitabine as a lung cancer chemotherapy medication publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2019.111611 – volume: 127 start-page: 362 year: 2007 ident: 10.1016/j.snb.2022.132552_bib18 article-title: Determination of paracetamol based on electropolymerized-molecularly imprinted polypyrrole modified pencil graphite electrode publication-title: Sens. Actuators B. doi: 10.1016/j.snb.2007.04.034 – volume: 127 start-page: 207 year: 2019 ident: 10.1016/j.snb.2022.132552_bib23 article-title: A robust electrochemical sensing of molecularly imprinted polymer prepared by using bifunctional monomer and its application in detection of cypermethrin publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2018.12.002 – volume: 1 start-page: 3325 year: 2019 ident: 10.1016/j.snb.2022.132552_bib31 article-title: Preparation and applications of electrochemical chemosensors based on carbon-nanomaterial-modified molecularly imprinted polymers publication-title: Nanoscale Adv. doi: 10.1039/C9NA00455F – volume: 286 start-page: 540 year: 2019 ident: 10.1016/j.snb.2022.132552_bib27 article-title: A novel electrochemical sensor based on GQDs-PANI/ZnO-NCs modified glassy carbon electrode for simultaneous determination of Irinotecan and 5-Fluorouracil in biological samples publication-title: Sens. Actuators B. doi: 10.1016/j.snb.2019.02.017 – volume: 28 start-page: 1429 year: 2017 ident: 10.1016/j.snb.2022.132552_bib42 article-title: Fabrication of the electrochemically reduced graphene oxide-bismuth nanoparticles composite and its analytical application for an anticancer drug gemcitabine publication-title: Chin. Chem. Lett. doi: 10.1016/j.cclet.2016.11.028 – volume: 307 year: 2020 ident: 10.1016/j.snb.2022.132552_bib28 article-title: A novel molecularly imprinted polymer decorated by CQDs@HBNNS nanocomposite and UiO-66-NH2 for ultra-selective electrochemical sensing of Oxaliplatin in biological samples publication-title: Sens. Actuators B. doi: 10.1016/j.snb.2019.127614 – volume: 224 start-page: 134 year: 2016 ident: 10.1016/j.snb.2022.132552_bib32 article-title: Optimization of stripping voltammetric sensor by mixture design-artificial neural network-genetic algorithm for determination of trace copper(II) based on iodoquinol-carbon nanotube modified carbon paste electrode publication-title: Sens. Actuators B. doi: 10.1016/j.snb.2015.09.154 – volume: 143 start-page: 2150 year: 2018 ident: 10.1016/j.snb.2022.132552_bib15 article-title: A ratiometric strategy -based electrochemical sensing interface for the sensitive and reliable detection of imidacloprid publication-title: Analyst doi: 10.1039/C8AN00111A – volume: 318 year: 2020 ident: 10.1016/j.snb.2022.132552_bib22 article-title: Ultra-sensitive molecularly imprinted electrochemical sensor for patulin detection based on a novel assembling strategy using Au@Cu-MOF/N-GQDs publication-title: Sens. Actuators B. doi: 10.1016/j.snb.2020.128219 – volume: 77 start-page: 145 year: 2010 ident: 10.1016/j.snb.2022.132552_bib43 article-title: Electrochemical behaviour of dimethyl-2-oxoglutarate on glassy carbon electrode publication-title: Bioelectrochemistry doi: 10.1016/j.bioelechem.2009.07.012 – volume: 357 year: 2021 ident: 10.1016/j.snb.2022.132552_bib29 article-title: Improved solid phase extraction for selective and efficient quantification of sunset yellow in different food samples using a novel molecularly imprinted polymer reinforced by Fe3O4@UiO-66-NH2 publication-title: Food Chem. doi: 10.1016/j.foodchem.2021.129782 – volume: 207 year: 2022 ident: 10.1016/j.snb.2022.132552_bib37 article-title: Sensitive and specific clinically diagnosis of SARS-CoV-2 employing a novel biosensor based on boron nitride quantum dots/flower-like gold nanostructures signal amplification publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2022.114209 – volume: 177 start-page: 871 year: 2013 ident: 10.1016/j.snb.2022.132552_bib40 article-title: Computer-aided sensor design and analysis of thiocarbohydrazide in biological matrices using electropolymerized-molecularly imprinted polypyrrole modified pencil graphite electrode publication-title: Sens. Actuators B. doi: 10.1016/j.snb.2012.11.103 – volume: 1190 year: 2022 ident: 10.1016/j.snb.2022.132552_bib14 article-title: A novel ratiometric electrochemical sensor based on dual-monomer molecularly imprinted polymer and Pt/Co3O4 for sensitive detection of chlorpromazine hydrochloride publication-title: Anal. Chim. Acta doi: 10.1016/j.aca.2021.339245 – volume: 840 start-page: 44 year: 2006 ident: 10.1016/j.snb.2022.132552_bib6 article-title: Simultaneous determination of gemcitabine di- and triphosphate in human blood mononuclear and cancer cells by RP-HPLC and UV detection publication-title: J. Chromatogr. B doi: 10.1016/j.jchromb.2006.04.036 – volume: 202 start-page: 240 year: 2014 ident: 10.1016/j.snb.2022.132552_bib19 article-title: Neuro-genetic multi-objective optimization and computer-aided design of pantoprazole molecularly imprinted polypyrrole sensor publication-title: Sens. Actuators B. doi: 10.1016/j.snb.2014.04.094 – volume: 19 start-page: 1933 year: 2013 ident: 10.1016/j.snb.2022.132552_bib3 article-title: Electro-oxidation and determination of gemcitabine hydrochloride, an anticancer drug at gold electrode publication-title: J. Ind. Eng. Chem. doi: 10.1016/j.jiec.2013.02.040 – volume: 7 start-page: 98 year: 2021 ident: 10.1016/j.snb.2022.132552_bib34 article-title: A review on the synthesis of CuCo2O4-based electrode materials and their applications in supercapacitors publication-title: J. Mater. – volume: 266 start-page: 514 year: 2018 ident: 10.1016/j.snb.2022.132552_bib4 article-title: Rapid determination of the anti-cancer agent Gemcitabine in biological samples by fluorescence sensor based on Au-doped CdTe publication-title: J. Mol. Liq. doi: 10.1016/j.molliq.2018.06.105 – volume: 100 start-page: 56 year: 2018 ident: 10.1016/j.snb.2022.132552_bib30 article-title: Recent advances and future prospects in molecularly imprinted polymers-based electrochemical biosensors publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2017.08.058 – volume: 208 year: 2022 ident: 10.1016/j.snb.2022.132552_bib25 article-title: Molecularly imprinted polymer-based extended-gate field-effect transistor (EG-FET) chemosensor for selective determination of matrix metalloproteinase-1 (MMP-1) protein publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2022.114203 – volume: 138 start-page: 71 year: 2015 ident: 10.1016/j.snb.2022.132552_bib5 article-title: Anticancer drug detection using a highly sensitive molecularly imprinted electrochemical sensor based on an electropolymerized microporous metal organic framework publication-title: Talanta doi: 10.1016/j.talanta.2015.01.013 – volume: 154 year: 2020 ident: 10.1016/j.snb.2022.132552_bib12 article-title: A signal on-off ratiometric electrochemical sensor coupled with a molecular imprinted polymer for selective and stable determination of imidacloprid publication-title: Biosens. Bioelectron. doi: 10.1016/j.bios.2020.112091 – volume: 877 start-page: 2123 year: 2009 ident: 10.1016/j.snb.2022.132552_bib10 article-title: Development of a sensitive and selective LC–MS/MS method for simultaneous determination of gemcitabine and 2,2-difluoro-2-deoxyuridine in human plasma publication-title: J. Chromatogr. B doi: 10.1016/j.jchromb.2009.06.002 – volume: 234 year: 2021 ident: 10.1016/j.snb.2022.132552_bib21 article-title: Dual-signaling electrochemical ratiometric strategy for simultaneous quantification of anticancer drugs publication-title: Talanta doi: 10.1016/j.talanta.2021.122662 – volume: 6 start-page: 16847 year: 2018 ident: 10.1016/j.snb.2022.132552_bib41 article-title: C3N4 nanosheets/metal–organic framework wrapped with molecularly imprinted polymer sensor: fabrication, characterization, and electrochemical detection of furosemide publication-title: ACS Sustain. Chem. Eng. doi: 10.1021/acssuschemeng.8b04179 |
| SSID | ssj0004360 |
| Score | 2.5133035 |
| Snippet | A novel and reliable electrochemical analysis tool was developed for gemcitabine (GEM) detection by combining the selective recognition of molecular imprinted... |
| SourceID | proquest crossref elsevier |
| SourceType | Aggregation Database Enrichment Source Index Database Publisher |
| StartPage | 132552 |
| SubjectTerms | Amplification Aniline CuCo2O4 Electrochemical analysis Gemcitabine Glassy carbon Imprinted polymers Molecularly imprinted polymer Nitrogen-doped carbon nanotubes Oxidation Ratiometric electrochemical sensor Reference signals Substrates |
| Title | A signal on-off ratiometric electrochemical sensing platform coupled with a molecularly imprinted polymer and CuCo2O4/NCNTs signal amplification for selective determination of gemcitabine |
| URI | https://dx.doi.org/10.1016/j.snb.2022.132552 https://www.proquest.com/docview/2734714291 |
| Volume | 371 |
| WOSCitedRecordID | wos000862175900007&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVESC databaseName: Elsevier SD Freedom Collection Journals 2021 customDbUrl: eissn: 1873-3077 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0004360 issn: 0925-4005 databaseCode: AIEXJ dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9NAEF6VlgMcEE9RKGgPnIgcnLWdzR7TqAgQBKQWqTdrX25SxU6VR9X2r_HXODDj3XXSVFSAxMWyEtvjZD7vzo6_-YaQN4rB0FgIGSUq1VHKTByhDFwkCiZjk3RTYWp1_c98OOwdH4tvW1s_Qy3M-YRXVe_iQpz9V1fDZ-BsLJ39C3c3F4UPYB-cDltwO2z_yPH9FnIyMMasomlRtGoXl9g4S7d80xsdVALmSF_HcvSJXGD02tLT5dkkMNJlqwzNcyeXWE85Q3EJg40dLkvryJeD5WDKvqZwu8PB8GgebEskqhc-H1hTGee1beQpmcDACcHqiS31eCFVeMXvY-VDuDlsBVTLyWKdCzYGarf2HUvA_YLVALqQ5WR5WXMT9u2okldN7kgaezK6gu3IpcDL8Uxe_3LsX4bZ8UhWtkmQfxnPAMknIxic3WPzZTqSZSkN7CivWO4TJrDWRtJetsri3ajkcelQlsFaOnbHWTcZ9HiCuTm-PlskrmPMjZnHJUFO2_NKtdFqG5b5mRPn3RD0PkRbaIqxWnBP3CE7jGeit012-h8Pjj-t6nqTusq9ubfwVr7mJ24Y-l1ctRFh1GHT0UPywK93aN_h9BHZstVjcn9NBfMJ-dGnDjXUIZauIZZuIJZ6xNKAWOoRSxGxVNI1xNIGsdQjlgKUqEfsuxqvwfI1vFK4MG3wSq_hlU4LuobXp-T7-4OjwYfI9xSJNPxLi4gzm1kJa_xuphTMZx3JVSFSxXkhDI8ZZ92OtIxxa2JhTJaY1HZlT2Vaad21OnlGtqtpZZ8T2i2SrNPTsYq1xHJRKSC0zzKjdUcJlYhdEgeP5NoL7mPfl0kemJWnOTgxRyfmzom75G1zyplTm7nt4DS4OffhsguDc8DkbaftBUjkftia5yhyxTsQm3Ze_NtVX5J7q2dtj2wvZkv7itzV54vxfPbaA_sXZzj4cg |
| linkProvider | Elsevier |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+signal+on-off+ratiometric+electrochemical+sensing+platform+coupled+with+a+molecularly+imprinted+polymer+and+CuCo2O4%2FNCNTs+signal+amplification+for+selective+determination+of+gemcitabine&rft.jtitle=Sensors+and+actuators.+B%2C+Chemical&rft.au=Hatamluyi%2C+Behnaz&rft.au=Sadeghzadeh%2C+Samira&rft.au=Sadeghian%2C+Reihaneh&rft.au=Mirimoghaddam%2C+Mohammad+Mobin&rft.date=2022-11-15&rft.pub=Elsevier+B.V&rft.issn=0925-4005&rft.eissn=1873-3077&rft.volume=371&rft_id=info:doi/10.1016%2Fj.snb.2022.132552&rft.externalDocID=S0925400522011959 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0925-4005&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0925-4005&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0925-4005&client=summon |