Development and validation of signature peptide-based isotope dilution liquid chromatography-mass spectrometry for bovine lactoferrin purity assessment

[Display omitted] •Signature peptide-based ID-LC-MS/MS for quantification of bovine lactoferrin was reported.•The two-stage IDMS that included the quantification of the synthetic peptide by AA-based IDMS and certification of bovine lactoferrin by signature peptide-based IDMS is fully SI-traceable.•T...

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Bibliographic Details

Published in:	Microchemical journal Vol. 208; p. 112458
Main Authors:	Yan, Jingjing, Yang, Mengrui, Wang, Min, Han, Yiyi, Zhou, Jian, Ma, Yingqing, Wang, Tongtong, Li, Liang
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 01.01.2025
Subjects:	Active concentration Bovine lactoferrin Isotope dilution mass spectrometry Protein quantification Signature peptide Isotope dilution mass spectrometry Bovine lactoferrin Signature peptide Active concentration Protein quantification
ISSN:	0026-265X
Online Access:	Get full text
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