Antiplatelet therapy does not influence outcome or host response biomarkers during sepsis: a propensity-matched analysis

Antiplatelet therapy was not related to sepsis severity at presentation, the primary source of infection, causative pathogens, the development of organ failure or shock during ICU stay, or mortality up to 90 days after admission, in either the unmatched or propensity-matched analyses. Acknowledgemen...

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Published in:Critical care (London, England) Vol. 19; no. Suppl 1; p. P30
Main Authors: Wiewel, MA, De Stoppelaar, SF, Van Vught, LA, Frencken, JF, Hoogendijk, AJ, Klouwenberg, PM Klein, Horn, J, Bonten, MJ, Schultz, MJ, Zwinderman, AH, Cremer, OL, Van der Poll, T
Format: Journal Article
Language:English
Published: London BioMed Central 16.03.2015
BioMed Central Ltd
Springer Nature B.V
Subjects:
Aggregation
Analysis
Biological markers
Biomarkers
Blood platelets
Clopidogrel
Critical Care Medicine
Drug therapy
Emergency Medicine
Health aspects
Health care delivery
Infection
Intensive
Medicine
Medicine & Public Health
Mortality
Patient outcomes
Pharmacology, Experimental
Physiological aspects
Poster Presentation
Sepsis
Netherlands
Propensity Score
Clopidogrel
Antiplatelet Therapy
Host Response
Dipyridamole
ISSN:1364-8535, 1364-8535, 1366-609X, 1466-609X
Online Access:Get full text
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Summary:Antiplatelet therapy was not related to sepsis severity at presentation, the primary source of infection, causative pathogens, the development of organ failure or shock during ICU stay, or mortality up to 90 days after admission, in either the unmatched or propensity-matched analyses. Acknowledgements This research was performed within the framework of CTMM, the Center for Translational Molecular Medicine (http://www.ctmm.nl), project MARS (grant 04I-201).
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ISSN:1364-8535
1364-8535
1366-609X
1466-609X
DOI:10.1186/cc14110