Investigation of Production Possibility of Medical Isotope 155Tb on Cyclotron C18/18

The results of the studies on the production of 155 Tb isotope, which is used in theranostic applications for oncological diseases, utilizing the proton beam of the medical cyclotron C18/18 are presented. The measurements of the induced activity were carried out using the activation method, followed...

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Bibliographic Details
Published in:Journal of contemporary physics Vol. 59; no. 1; pp. 17 - 22
Main Authors: Avetisyan, R. V., Barseghyan, A. G., Gharibyan, Yu. H., Gyurjinyan, A. V., Kerobyan, I. A., Mkrtchyan, H. A., Petrosyan, A. Yu
Format: Journal Article
Language:English
Published: Moscow Pleiades Publishing 01.03.2024
Springer Nature B.V
Subjects:
Aluminum
Copper
Cyclotrons
Efficiency
Energy
Gadolinium
Isotopes
Particle and Nuclear Physics
Physics
Physics and Astronomy
Proton beams
Radioisotopes
Sensors
Spectrometry
Spectrum analysis
Tomography
theranostic isotope
activation technique
cyclotron C18/18
product yield
ISSN:1068-3372, 1934-9378
Online Access:Get full text
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Summary:The results of the studies on the production of 155 Tb isotope, which is used in theranostic applications for oncological diseases, utilizing the proton beam of the medical cyclotron C18/18 are presented. The measurements of the induced activity were carried out using the activation method, followed by spectrometric analysis. Natural gadolinium was used as the main target. Excitation functions were calculated for the nat Gd( p , xn ) 155 Tb reactions using TALYS 1.96 and EMPIRE 3.2 theoretical nuclear codes. The measured cross-section values were compared with the results of the theoretical calculations as well as with the experimental data from other works. The experimental value of the integral activity of the radionuclide 155 Tb was compared to the results obtained with the TALYS 1.96 code and with early published data.
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ISSN:1068-3372
1934-9378
DOI:10.1134/S1068337224700038