Stability of 19-norandrosterone and 19-noretiocholanolone glucuronide in urine under various storage conditions

The International Olympic Committee (IOC) has ruled that 19-norandrosterone should be quantified if present in low concentrations in urine of sport competitors. The question, however, is how stable is 19-norandrosterone in urine. In the light of this IOC ruling it is therefore important to know if t...

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Bibliographic Details
Published in:South African journal of sports medicine Vol. 15; no. 2; pp. 14 - 17
Main Author: Van Der Merwe, P.J. & Grobbelaar, E.
Format: Journal Article
Language:English
Published: Sandton South African Sports Medicine Association 20.12.2003
Health and Medical Publishing Group
Subjects:
accuracy
Bacterial degradation
Chromatography
Derivatisation
Freeze and thaw stability
Hydrolysis
Liquid-liquid extraction
Long-term stability in freezer
Sample storage
Short term stability at room temperature
Solid phase extraction
Sports medicine
Testing method
ISSN:1015-5163, 2078-516X
Online Access:Get full text
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Summary:The International Olympic Committee (IOC) has ruled that 19-norandrosterone should be quantified if present in low concentrations in urine of sport competitors. The question, however, is how stable is 19-norandrosterone in urine. In the light of this IOC ruling it is therefore important to know if the concentration of 19-norandrosterone can change during the transportation process of urine samples to the laboratory or during the handling and storage of the samples in the laboratory.
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content type line 14
ISSN:1015-5163
2078-516X
DOI:10.17159/2078-516X/2003/v15i2a217