Characterisation of the divalent cation channels of the hepatocyte plasma membrane receptor-activated Ca2+ inflow system using lanthanide ions

The ability of Gd3+ to inhibit vasopressin-stimulated Ca2+ inflow to hepatocytes was compared with its effect on Mn2+ inflow. In the absence of Gd3+, the stimulation of Mn2+ inflow by vasopressin increased with increasing pH of the extracellular medium. Maximal inhibition of vasopressin-stimulated C...

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Bibliographic Details
Published in:	Biochimica et biophysica acta Vol. 1268; no. 1; pp. 97 - 106
Main Authors:	Fernando, Kekulu C., Barritt, Greg J.
Format:	Journal Article
Language:	English
Published:	Netherlands 20.07.1995
Subjects:	Animals Binding, Competitive Calcium - metabolism Calcium Channels - drug effects Calcium-Transporting ATPases - antagonists & inhibitors Cations - pharmacology Cell Membrane - metabolism Cells, Cultured Hydrogen-Ion Concentration Ion Channels - drug effects Kinetics Liver - cytology Liver - metabolism Manganese - metabolism Membrane Potentials Metals, Rare Earth - pharmacology Potassium - metabolism Rats Terpenes - pharmacology Thapsigargin Vasopressins - pharmacology
ISSN:	0167-4889, 0006-3002
Online Access:	Get full text
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